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World Hand Hygiene Day 2023 | Collections | MSF Science Portal
World Hand Hygiene Day 2023

World Hand Hygiene Day 2023

"Clean hands, safe care" is the theme of this year's World Hand Hygiene Day. At MSF, we know that Hand Hygiene is the simplest and best way to prevent the transmission of infections in our facilities. This collection features some lessons learned about hand hygiene and infection, prevention, & control (IPC) in MSF projects, especially in resource-constrained environments in the Sahel, and in the era of COVID-19.

Collection Content

Journal Article
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Research

Achieving minimum standards for infection prevention and control in Sierra Leone: urgent need for a quantum leap in progress in the COVID-19 era!

Fofanah BD, Abrahamyan A, Maruta A, Kallon C, Thekkur P,  et al.
2022-05-06 • International Journal of Environmental Research and Public Health
2022-05-06 • International Journal of Environmental Research and Public Health
INTRODUCTION
Good Infection prevention and control (IPC) is vital for tackling antimicrobial resistance and limiting health care-associated infections. We compared IPC performance be...
Journal Article
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Research

An exploratory qualitative study of caregivers' knowledge, perceptions and practices related to hospital hygiene in rural Niger

Marquer C, Guindo O, Mahamadou I, Job E, Rattigan SM,  et al.
2021-09-01 • Infection Prevention in Practice
2021-09-01 • Infection Prevention in Practice
BACKGROUND
The risk of healthcare-associated infections is exacerbated by poor hygiene practices in health care facilities and can contribute to increased patient morbidity and morta...
Journal Article
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Commentary

How COVID-19 highlighted the need for infection prevention and control measures to become central to the global conversation: experience from the conflict settings of the Middle East

Mouallem RE, Moussally K, Williams A, Repetto EC, Menassa M,  et al.
2021-08-19 • International Journal of Infectious Diseases
2021-08-19 • International Journal of Infectious Diseases
The COVID-19 pandemic has managed to bring to the foreground, in just few months, the conversation around what Infection Prevention and Control (IPC) experts have been pushing for decade...
Journal Article
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Research

Hand hygiene compliance and environmental contamination with gram-negative bacilli in a rural hospital in Madarounfa, Niger

Tang K, Berthé F, Nackers F, Hanson KE, Mambula C,  et al.
2019-10-14 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2019-10-14 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Background
Healthcare-associated infections pose a major, yet often preventable risk to patient safety. Poor hand hygiene among healthcare personnel and unsanitary hospital environm...
Journal Article
|
Research

Inclusion of real-time hand hygiene observation and feedback in a multimodal hand hygiene improvement strategy in low-resource settings

Lenglet AD, van Deursen B, Viana R, Abubakar N, Hoare S,  et al.
2019-08-02 • Journal of the American Medical Association (JAMA)
2019-08-02 • Journal of the American Medical Association (JAMA)
IMPORTANCE
Hand hygiene adherence monitoring and feedback can reduce health care-acquired infections in hospitals. Few low-cost hand hygiene adherence monitoring tools exist in low-r...

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World Hepatitis Day 2022

World Hepatitis Day 2022
Each year hundreds of millions of people suffer from chronic or acute liver disease caused by hepatitis viruses, and over one million die. To mark World Hepatitis Day (July 28th) we bring you a selection of MSF research exploring how to better prevent, identify and treat hepatitis infection in lower-income countries and emergency contexts where the burden is heaviest. For example, in a South Sudanese camp for displaced people—a type of setting where poor sanitation and water quality regularly lead to hepatitis E outbreaks—MSF and the Ministry of Health (MoH) are conducting the world’s first reactive vaccination campaign against this disease, and evaluating the process and outcomes. In Cambodia, MSF and MoH collaborators found that a simplified community-based model of care for hepatitis C was safe and highly effective in diagnosing patients and in curing them with new antiviral drugs. It was also cost-effective, according to studies in several countries and patient populations. And these new drugs were safe and effective even in patients also being treated for drug-resistant tuberculosis.
The endTB project

The endTB project

The endTB project aims to find shorter, less toxic and more effective treatments for ‘multidrug-resistant TB’ (MDR-TB) through:

  • access to new drugs
  • two clinical trials
  • advocacy at national and global levels

Covering 18 countries, the project is a partnership between Partners In Health, Médecins Sans Frontières, Interactive Research & Development and financial partners Unitaid and the Transformational Investment Capacity (TIC) of MSF. This collection contains the final and intermediate results of the studies, advocacy reports, and study presentations. For more information about the endTB project, visit https://endtb.org/.

TB-PRACTECAL Trial—Evidence for a shorter, safer, more effective treatment for drug-resistant tuberculosis

TB-PRACTECAL Trial—Evidence for a shorter, safer, more effective treatment for drug-resistant tuberculosis
Drug-resistant tuberculosis (DR-TB) remains an especially deadly form of the ancient scourge of TB, while current treatments are long, toxic, and ineffective for half of all patients. Aiming to change this unacceptable status quo, in the mid-2010’s MSF and partners launched three clinical trials to test novel regimens containing the first new TB drugs in decades. On 22 December 2022 the New England Journal of Medicine published findings from TB-PRACTECAL, a three-country randomized controlled trial, showing that a shorter regimen is safer and cured 89% of DR-TB patients, compared with 52% on the standard of care. These findings have already been incorporated into the World Health Organization’s new TB treatment guidelines. A separate study shows that the new regimen is also more cost-effective. Alongside these results the content collection linked below highlights other aspects of the trial, from community engagement strategies that helped shape TB-PRACTECAL to setbacks arising from the Covid-19 pandemic. It also examines urgent challenges in scaling up access to these life-saving drugs, including affordability and patent barriers.
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