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Journal Article
|Research

Use of a Cholera Rapid Diagnostic Test during a Mass Vaccination Campaign in Response to an Epidemic in Guinea, 2012

Martinez-Pino I, Luquero FJ, Sakoba K, Sylla S, Haile M, Grais RF, Ciglenecki I, Quilici ML, Page AL
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Abstract
During the 2012 cholera outbreak in the Republic of Guinea, the Ministry of Health, supported by Médecins Sans Frontières - Operational Center Geneva, used the oral cholera vaccine Shanchol as a part of the emergency response. The rapid diagnostic test (RDT) Crystal VC, widely used during outbreaks, detects lipopolysaccharide antigens of Vibrio cholerae O1 and O139, both included in Shanchol. In the context of reactive use of a whole-cell cholera vaccine in a region where cholera cases have been reported, it is essential to know what proportion of vaccinated individuals would be reactive to the RDT and for how long after vaccination.

Countries

Guinea

Subject Area

vaccinationdiagnosticsoutbreakscholera

Languages

English
DOI
10.1371/journal.pntd.0002366
Published Date
15 Aug 2013
PubMed ID
23967359
Journal
PLOS Neglected Tropical Diseases
Volume | Issue | Pages
Volume 7, Issue 8
Issue Date
2013-08-15
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Use of a Cholera Rapid Diagnostic Test during a Mass Vaccination Campaign in Response to an Epidemic in Guinea, 2012 | Journal Article / Research | MSF Science Portal