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Journal Article > Research

Intensive-Phase Treatment Outcomes among Hospitalized Multidrug-Resistant Tuberculosis Patients: Results from a Nationwide Cohort in Nigeria

Oladimeji O, Isaakidis P, Obasanya OJ, Eltayeb O, Khogali MA, Van der Bergh R, Kumar AMV, Hinderaker SG, Abdurrahman ST, Lawson L, Cuevas LE
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Abstract
Nigeria is faced with a high burden of Human Immunodeficiency Virus (HIV) infection and multidrug-resistant tuberculosis (MDR-TB). Treatment outcomes among MDR-TB patients registered across the globe have been poor, partly due to high loss-to-follow-up. To address this challenge, MDR-TB patients in Nigeria are hospitalized during the intensive-phase(IP) of treatment (first 6-8 months) and are provided with a package of care including standardized MDR-TB treatment regimen, antiretroviral therapy (ART) and cotrimoxazole prophylaxis (CPT) for HIV-infected patients, nutritional and psychosocial support. In this study, we report the end-IP treatment outcomes among them.
Countries
Nigeria
Subject Area
antibiotic resistancetuberculosisSORT-ITantimicrobial resistanceHIV/AIDS
DOI
10.1371/journal.pone.0094393
Published Date
10-Apr-2014
PubMed ID
24722139
Languages
English
Journal
PLOS One
Volume / Issue / Pages
Volume 9, Issue 4
Issue Date
10-Apr-2014
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