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Journal Article > Short Report

Emergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report

Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L, Magassouba N, Soropogui B, Sow MS, Keita S, Tiffany A, Dominguez G, Loua M, Traore A, Kolie MC, Malano ER, Heleze E, Bocquin A, Mely S, Raoul H, Caro V, Cadar D, Gabriel M, Pahlmann M, Tappe D, Schmit-Chanasit J, Impouma B, Diallo AK, Formenty P, Van Herp M, Gunther S
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Abstract
In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Full-length genome sequencing and phylogenetic analysis showed that EBOV from Guinea forms a separate clade in relationship to the known EBOV strains from the Democratic Republic of Congo and Gabon. Epidemiologic investigation linked the laboratory-confirmed cases with the presumed first fatality of the outbreak in December 2013. This study demonstrates the emergence of a new EBOV strain in Guinea.
Countries
Guinea
Subject Area
Ebolaviral hemorrhagic diseasesoutbreaksinfections, viral
DOI
10.1056/NEJMoa1404505
Published Date
09-Oct-2014
PubMed ID
24738640
Languages
English
Journal
New England Journal of Medicine
Volume / Issue / Pages
Volume 371, Issue 15, Pages 1418-1425
Issue Date
09-Oct-2014
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