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Journal Article > Research

Diphtheria outbreak with high mortality in northeastern Nigeria

Besa NC, Coldiron ME, Bakri A, Raji A, Nsuami MJ, Rousseau C, Hurtado N, Porten K
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Abstract
SUMMARY A diphtheria outbreak occurred from February to November 2011 in the village of Kimba and its surrounding settlements, in Borno State, northeastern Nigeria. We conducted a retrospective outbreak investigation in Kimba village and the surrounding settlements to better describe the extent and clinical characteristics of this outbreak. Ninety-eight cases met the criteria of the case definition of diphtheria, 63 (64·3%) of whom were children aged <10 years; 98% of cases had never been immunized against diphtheria. None of the 98 cases received diphtheria antitoxin, penicillin, or erythromycin during their illness. The overall case-fatality ratio was 21·4%, and was highest in children aged 0-4 years (42·9%). Low rates of immunization, delayed clinical recognition of diphtheria and absence of treatment with antitoxin and appropriate antibiotics contributed to this epidemic and its severity.
Countries
Nigeria
Subject Area
outbreaksinfections, other
DOI
10.1017/S0950268813001696
Published Date
18-Jul-2013
PubMed ID
23866913
Languages
English
Journal
Epidemiology and Infection
Volume / Issue / Pages
Volume 142, Issue 4
Issue Date
18-Jul-2013
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