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v2.1.5401.produseast1
Showing 1 - 20 of 929 Items
Showing 1 - 20 of 929 Items
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Journal Article
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Research

Effectiveness of the primary Bacillus Calmette-Guérin vaccine against the risk of Mycobacterium tuberculosis infection and tuberculosis disease: a meta-analysis of individual participant data

Pelzer PT, Stuck L, Martinez L, Richards AS, Acuña-Villaorduña C,  et al.
2024-12-19 • Lancet Microbe
2024-12-19 • Lancet Microbe

BACKGROUND

Tuberculosis vaccine trials using disease as the primary endpoint are large, time consuming, and expensive. An earlier immunological measure of the p...

Journal Article
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Letter

Sustained treatment success at 12 months for drug-resistant TB patients on concomitant bedaquiline-delamanid

Chavan V, Silsarma A, Mahajan R, Khan S, Singh P,  et al.
2025-02-01 • IJTLD OPEN
2025-02-01 • IJTLD OPEN
Journal Article
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Research

Decentralising TB diagnosis and contact management: impact on detection and preventive treatment in children

Delmas V, Vasiliu A, Tchakounté Youngui B, Ssekyanzi B, Kuate Kuate A,  et al.
2025-06-27 • International Journal of Tuberculosis and Lung Disease
2025-06-27 • International Journal of Tuberculosis and Lung Disease

BACKGROUND

The ‘CaP-TB’ project enhanced paediatric TB care through decentralized services, including screening, specimen collection, chest X-rays and implement...

Journal Article
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Review

Clinical best practices for caring for people with expanded resistance to newer TB drugs

Nkomo T, Udwadia Z, Vambe D, van Rie A, Thi S,  et al.
2025-06-13 • IJTLD OPEN
2025-06-13 • IJTLD OPEN

BACKGROUND

Strains of Mycobacterium tuberculosis

Conference Material
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Slide Presentation

Implementation of treatment-decision algorithms for children with pulmonary tuberculosis: cross-cutting lessons for operational scale-up

Armour-Marshall J, Scarpa G, Abdullahi MB, Farouk Moussa Mamane O, Fidelle Nyikayo L,  et al.
2025-05-22 • MSF Scientific Days International 2025
2025-05-22 • MSF Scientific Days International 2025
Journal Article
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Research

Second-line drug-resistant TB and associated risk factors in Karakalpakstan, Uzbekistan

Moe S, Azamat I, Allamuratova S, Oluya M, Khristusev A,  et al.
2024-09-01 • IJTLD OPEN
2024-09-01 • IJTLD OPEN

BACKGROUND

Dru...

Journal Article
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Research

Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis

Guglielmetti L, Khan U, Velásquez GE, Gouillou M, Abubakirov A,  et al.
2025-01-29 • New England Journal of Medicine
2025-01-29 • New England Journal of Medicine

BACKGROUND

For decades, poor treatment options and low-quality evidence plagued care for patients with rifampin-resistant tuberculosis. The advent of new drugs ...

Journal Article
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Commentary

Leveraging nutritional rehabilitation and tuberculosis programmes to tackle tuberculosis and severe acute malnutrition in children

Vonasek BJ, Marcy O, Armour J, Casenghi M, Cazes C,  et al.
2025-03-23 • Lancet Child and Adolescent Health
2025-03-23 • Lancet Child and Adolescent Health

Each day more than 500 children younger than 15 years die from tuberculosis. Considerable progress has been...

Journal Article
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Research

Bedaquiline, delamanid, linezolid, and clofazimine for rifampicin-resistant and fluoroquinolone-resistant tuberculosis (endTB-Q): an open-label, multicentre, stratified, non-inferiority, randomised, controlled, phase 3 trial

Guglielmetti L, Khan U, Velásquez GE, Gouillou M, Ali MH,  et al.
2025-07-16 • Lancet Respiratory Medicine
2025-07-16 • Lancet Respiratory Medicine
Journal Article
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Research

Concomitant splenic tuberculosis and Epstein–Barr virus-related T-cell leukemia/lymphoma in a 28-year-old pregnant woman in South Sudan

Wild HB, Aumuller J, Kuei J, Simon M, Palm A,  et al.
2025-06-04 • American Journal of Tropical Medicine and Hygiene
2025-06-04 • American Journal of Tropical Medicine and Hygiene

This case report presents a rare instance of concomitant splenic tuberculosis (TB), Epstein–Barr virus (EBV)-related T-cell leukemia/lymphoma, and malaria in a 28-year-old pregnant wo...

Journal Article
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Research

Cost analysis of the TB-PRACTECAL clinical trial on novel tuberculosis treatment regimens

Gotham D, Martin M, Barber MJ, Kazounis E, Batts C,  et al.
2025-04-23 • PLOS Global Public Health
2025-04-23 • PLOS Global Public Health

Clinical trials are considered to be the largest contributor to pharmaceutical development costs. However, public disclosure of the costs of individual clinical trials is rare. Médec...

Journal Article
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Review

Optimal dosing and duration of linezolid for the treatment of multidrug-resistant and rifampicin-resistant tuberculosis: An individual patient data meta-analysis

Kwak N, Kim JY, Han A, Berry C, Beumont M,  et al.
2025-07-17 • European Respiratory Journal
2025-07-17 • European Respiratory Journal

BACKGROUND

The optimal dosing strategy of linezolid for treating multidrug-resistant and rifampicin-resistant tuberculosis (MDR/RR-TB) remains unclear. We condu...

Conference Material
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Abstract

Implementation of treatment-decision algorithms for children with pulmonary tuberculosis: cross-cutting lessons for operational scale-up

Armour-Marshall J, Scarpa G, Abdullahi MB, Farouk Moussa Mamane O, Fidelle Nyikayo L,  et al.
2025-05-22 • MSF Scientific Days International 2025
2025-05-22 • MSF Scientific Days International 2025
Journal Article
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Research

Centrifuge-free stool processing methods for Xpert MTB/RIF Ultra tuberculosis diagnosis in children in Uganda and Zambia: an observational, prospective, diagnostic accuracy study

Lounnas M, Masama EN, Beneteau S, Kasakwa K, Kaitano R,  et al.
2025-06-01 • Lancet Microbe
2025-06-01 • Lancet Microbe

BACKGROUND

WHO recommends Xpert MTB/RIF Ultra (Ultra) for stool testing for tuberculosis diagnosis in children. Stool processing requires removal of debris and ...

Journal Article
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Commentary

Equitable, personalised medicine for tuberculosis: Treating patients, not diseases

Guglielmetti L, Panda S, Abubakirov A, Salahuddin N, Perrin C,  et al.
2025-03-21 • Lancet Respiratory Medicine
2025-03-21 • Lancet Respiratory Medicine
Journal Article
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Research

End of treatment and 12-month post-treatment outcomes in patients treated with all-oral regimens for rifampicin-resistant tuberculosis in Ukraine: a prospective cohort study

Fardhdiani V, Trush O, Lytvynenko N, Pylypchuk S, Terleeva Y,  et al.
2025-05-23 • PLOS Global Public Health
2025-05-23 • PLOS Global Public Health

The World Health Organization has called for operational research on all-oral shorter regimens for rifampin-resistant and multidrug-resistant forms of tuberculosis (RR/MDR-TB). We fol...

Journal Article
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Research

The frequency and incidence of QT prolongation with extended use of bedaquiline or delamanid in a large, multi-country multidrug-resistant/rifampicin-resistant tuberculosis cohort

Khan U, Rich M, Franke MF, Lachenal N, Ahmed S,  et al.
2025-08-01 • Clinical Infectious Diseases
2025-08-01 • Clinical Infectious Diseases

BACKGROUND

The 2022 World Health Organization (WHO) guidelines on multidrug-resistant/rifampicin-resistant tubercul...

Journal Article
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Case Report/Series

Concomitant splenic tuberculosis and Epstein-Barr virus-related T-cell leukemia/lymphoma in a 28-year-old pregnant woman in South Sudan

Wild HB, Aumuller J, Kuei J, Simon M, Palm A,  et al.
2025-04-15 • American Journal of Tropical Medicine and Hygiene
2025-04-15 • American Journal of Tropical Medicine and Hygiene

This case report presents a rare instance of concomitant splenic tuberculosis (TB), Epstein–Barr virus (EBV)-related T-cell leukemia/lymphoma, and malaria in a 28-year-old pregnant wo...

Journal Article
|
Research

Body mass index trajectories and association with tuberculosis risk in a cohort of household contacts in Southern Africa

Larsson L, Calderwood CJ, Marambire ET, Held K, Banze D,  et al.
2025-04-28 • Clinical Infectious Diseases
2025-04-28 • Clinical Infectious Diseases

BACKGROUND

Studies have demonstrated an inverse log-linear relationship between body mass index (BMI) and tuberculosis incidence. However, a person’s BMI is dyn...

Journal Article
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Research

Implementation of digital chest radiography for childhood tuberculosis diagnosis at district hospital level in six high tuberculosis burden and resources limited countries

Melingui BF, Basant J, Taguebue Jv, Massom DM, Leroy Terquem E,  et al.
2024-11-03 • Journal of Tropical Medicine
2024-11-03 • Journal of Tropical Medicine

OBJECTIVES

Chest x‐ray (CXR) plays an important role in childhood tuberculosis (TB) diagnosis, but access to quality CXR remains a major challenge in resource‐l...