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Showing 1 - 12 of 12 Items
Showing 1 - 12 of 12 Items
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Journal Article
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Research

Mycoplasma genitalium infection in Eswatini amid syndromic case management: Prevalence, coinfections, diagnostic challenges and treatment gaps

Kerschberger B, Lekelem S, Daka M, Ntshalintshali N, Mabhena E,  et al.
2025-04-17 • BMC Infectious Diseases
2025-04-17 • BMC Infectious Diseases

BACKGROUND

The global epidemic of Mycoplasma genitalium (MG) is marked by its widespread prevalence, varied resistance patterns, and significant impact on sexua...

Journal Article
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Research

Effectiveness of blood transfusions and risk factors for mortality in children aged from 1 month to 4 years at the Bon Marche Hospital, Bunia, Democratic Republic of Congo

Mueller YK, Bastard M, Ehounou G, Itama J, Quere M,  et al.
2012-10-11 • Tropical Medicine and International Health
2012-10-11 • Tropical Medicine and International Health
Objective  To assess the effectiveness of blood transfusions in a hospital of north-eastern Democratic Republic of the Congo. Methods  Prospective study of children admitted for severe a...
Journal Article
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Research

High prevalence of multidrug-resistant tuberculosis, Swaziland, 2009-2010

Sanchez-Padilla E, Dlamini T, Ascorra A, Rusch-Gerdes S, Tefera ZD,  et al.
2012-01-01 • Emerging Infectious Diseases
2012-01-01 • Emerging Infectious Diseases
In Africa, although emergence of multidrug-resistant (MDR) tuberculosis (TB) represents a serious threat in countries severely affected by the HIV epidemic, most countries lack drug-resi...
Journal Article
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Research

Field suitability and diagnostic accuracy of the Biocentric open real-time PCR platform for plasma-based HIV viral load quantification in Swaziland

Mpala Q, Maphalala G, Uribe PAD, de la Tour R, Kalombola S,  et al.
2018-11-14 • BMC Infectious Diseases
2018-11-14 • BMC Infectious Diseases
Viral load (VL) testing is being scaled up in resource-limited settings. However, not all commercially available VL testing methods have been evaluated under field conditions. This study...
Journal Article
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Research

Field suitability and diagnostic accuracy of the Biocentric open real-time PCR platform for dried blood spot-based HIV viral load quantification in Eswatini

Kerschberger B, Ntshalintshali N, Mpala Q, Diaz Uribe PA, Maphalala G,  et al.
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND
To assess the performance and suitability of dried blood spot (DBS) sampling using filter paper to collect blood for viral load (VL) quantification under routine condition...
Conference Material
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Abstract

Diagnostic performance of lateral flow point-of-care HIV-Combo testing for detection of acute HIV infection in Eswatini

Kerschberger B, Ntshalintshali N, Maphalala G, Aung A, Mamba C,  et al.
2021-05-19 • MSF Scientific Days International 2021: Research
2021-05-19 • MSF Scientific Days International 2021: Research
INTRODUCTION
Acute HIV infection (AHI) is rarely diagnosed in resource-limited settings. Barriers to diagnosis include the high costs of viral load (VL)-based diagnostic testing algo...
Conference Material
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Poster

Establishment of a predictor risk score for the prioritization of patients for testing for acute HIV infection

Kerschberger B, Mpala Q, Aung A, Ntshalintshali N, Mamba C,  et al.
2021-05-18 • MSF Scientific Days International 2021: Research
2021-05-18 • MSF Scientific Days International 2021: Research
Journal Article
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Research

Routine use of Xpert MTB/RIF in areas with different prevalences of HIV and drug-resistant tuberculosis

Page AL, Ardizzoni E, Lassovsky M, Kirubi B, Bichkova D,  et al.
2015-06-30 • International Journal of Tuberculosis and Lung Disease
2015-06-30 • International Journal of Tuberculosis and Lung Disease
SETTING
Despite the widespread introduction of Xpert® MTB/RIF in developing countries, reports of its use and value in routine conditions remain limited.

OBJECTIVE
To de...
Journal Article
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Research

Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger

Coldiron ME, Assao B, Langendorf C, Sayinzoga-Makombe N, Ciglenecki I,  et al.
2019-12-26 • Malaria Journal
2019-12-26 • Malaria Journal
BACKGROUND
Rapid diagnostic tests (RDT) for malaria are common, but their performance varies. Tests using histidine-rich protein 2 (HRP2) antigen are most common, and many have high ...
Journal Article
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Research

Development of a target product profile for a point-of-care cardiometabolic device

Vetter B, Beran D, Boulle P, Chua AC, de la Tour R,  et al.
2021-10-09 • BMC Cardiovascular Disorders
2021-10-09 • BMC Cardiovascular Disorders
INTRODUCTION
Multi-parameter diagnostic devices can simplify cardiometabolic disease diagnosis. However, existing devices may not be suitable for use in low-resource settings, where ...
Journal Article
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Research

Predicting, diagnosing, and treating acute and early HIV infection in a public sector facility in Eswatini

Kerschberger B, Aung A, Mpala Q, Ntshalintshali N, Mamba C,  et al.
2021-12-15 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
2021-12-15 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
BACKGROUND
The lack of acute and early HIV infection (AEHI) diagnosis and care contributes to high HIV incidence in resource-limited settings. We aimed to assess the yield, predict a...
Conference Material
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Slide Presentation

Diagnostic performance of lateral flow point-of-care HIV-Combo testing for detection of acute HIV infection in Eswatini

Kerschberger B, Ntshalintshali N, Maphalala G, Aung A, Mamba C,  et al.
2021-05-19 • MSF Scientific Days International 2021: Research
2021-05-19 • MSF Scientific Days International 2021: Research