Smithuis FM, Shahmanesh M, Kyaw MK, Savran O, Lwin S, et al.
2004-11-01 • Tropical Medicine and International Health
2004-11-01 • Tropical Medicine and International Health
Multi-drug resistant falciparum malaria is widespread in Asia. In Thailand, Cambodia and Vietnam the national protocols have changed largely to artesunate combined treatment regimens but...
Smithuis FM, Kyaw MK, van der Broek I, Katterman N, Rogers C, et al.
2013-10-11 • Malaria Journal
2013-10-11 • Malaria Journal
BACKGROUND Insecticide-treated bed nets (ITN) reduce malaria morbidity and mortality consistently in Africa, but their benefits have been less consistent in Asia. This study's object...
Taylor WRJ, Hoglund RM, Peerawaranun P, Nguyen TN, Hien TT, et al.
2021-09-09 • Malaria Journal
2021-09-09 • Malaria Journal
BACKGROUND In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure recommend fixed tar...
Tun NL, London N, Kyaw MK, Smithuis FM, Ford NP, et al.
2011-08-15 • Journal of the International AIDS Society
2011-08-15 • Journal of the International AIDS Society
Cytomegalovirus retinitis is a neglected disease in resource-poor settings, in part because of the perceived complexity of care and because ophthalmologists are rarely accessible. In thi...
WorldWide Antimalarial Resistance Network Methodology Study Group, Dahal P, Simpson JA, Abdulla S, Achan J, et al.
2019-07-05 • Malaria Journal
2019-07-05 • Malaria Journal
BACKGROUND Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potenti...
Anderson TJC, Nair SA, Sudimack D, Williams JT, Mayxay M, et al.
2005-12-01 • Molecular Biology and Evolution
2005-12-01 • Molecular Biology and Evolution
Loci targeted by directional selection are expected to show elevated geographical population structure relative to neutral loci, and a flurry of recent papers have used this rationale to...
Smithuis FM, Monti F, Grundl M, Oo AZ, Kyaw TT, et al.
2008-02-07 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-02-07 • Transactions of the Royal Society of Tropical Medicine and Hygiene
In Rakhine State, on the western border of Myanmar, the efficacy of chloroquine (CQ) and pyrimethamine/ sulfadoxine (PS), the current treatments for uncomplicated Plasmodium falciparum m...
Smithuis FM, Kyaw MK, Phe O, Win T, Aung PP, et al.
2010-10-01 • Lancet Infectious Diseases
2010-10-01 • Lancet Infectious Diseases
BACKGROUND: Artemisinin-combination therapy (ACT) is recommended as first-line treatment of falciparum malaria throughout the world, and fixed-dose combinations are preferred by WHO; whe...
Zwang J, Ashley EA, Karema C, D'Alessandro U, Smithuis FM, et al.
2009-07-29 • PLOS One
2009-07-29 • PLOS One
BACKGROUND: The fixed dose antimalarial combination of dihydroartemisinin-piperaquine (DP) is a promising new artemisinin-based combination therapy (ACT). We present an individual patien...
Stepniewska K, Taylor WRJ, Mayxay M, Price RN, Smithuis FM, et al.
2004-11-01 • Antimicrobial Agents and Chemotherapy
2004-11-01 • Antimicrobial Agents and Chemotherapy
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with foll...
Grist EP, Fleqq JA, Humphreys G, Mas IS, Anderson TJC, et al.
2016-10-24 • International Journal of Health Geographics
2016-10-24 • International Journal of Health Geographics
BACKGROUND Artemisinin-resistant Plasmodium falciparum malaria parasites are now present across much of mainland Southeast Asia, where ongoing surveys are measuring and mapping their...
Lee SJ, Stepniewska K, Anstey NM, Ashley EA, Barnes KI, et al.
2008-08-01 • Malaria Journal
2008-08-01 • Malaria Journal
BACKGROUND: Malaria is a very important cause of anaemia in tropical countries. Anaemia is assessed either by measurement of the haematocrit or the haemoglobin concentration. For compari...
Stepniewska K, Ashley EA, Lee SJ, Anstey NM, Barnes KI, et al.
2010-02-15 • Journal of Infectious Diseases
2010-02-15 • Journal of Infectious Diseases
Parasite clearance data from 18,699 patients with falciparum malaria treated with an artemisinin derivative in areas of low (n=14,539), moderate (n=2077), and high (n=2083) levels of mal...
Hossain MS, Commons RJ, Douglas NM, Thriemer KL, Alemayehu BH, et al.
2020-11-19 • PLOS Medicine
2020-11-19 • PLOS Medicine
Background: There is a high risk of Plasmodium vivax parasitaemia following treatment of falciparum malaria. Our study aimed to quantify this risk and the associated determinants using a...
Smithuis FM, Kyaw MK, Phe O, Aye KZ, Htet L, et al.
2006-06-24 • Lancet
2006-06-24 • Lancet
BACKGROUND: Artemisinin-based combinations are judged the best treatments for multidrug-resistant Plasmodium falciparum malaria. Artesunate-mefloquine is widely recommended in southeast ...
