Showing 1 - 20 of 27 Items
Showing 1 - 20 of 27 Items
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Journal Article
|Research
2019-03-12 • PLOS One
2019-03-12 • PLOS One
BACKGROUND
HIV and TB programs have rapidly scaled-up over the past decade in Sub-Saharan Africa and uninterrupted supplies of those medicines are critical to their success. However,...
HIV and TB programs have rapidly scaled-up over the past decade in Sub-Saharan Africa and uninterrupted supplies of those medicines are critical to their success. However,...
Journal Article
|Research
2019-03-20 • JMIR Public Health Surveill
2019-03-20 • JMIR Public Health Surveill
The move toward universal provision of antiretroviral therapy and the expansion of HIV viral load monitoring call into question the ongoing value of CD4 cell count testing and monitoring...
Journal Article
|Research
2019-11-08 • Southern African Journal of HIV medicine
2019-11-08 • Southern African Journal of HIV medicine
Journal Article
|Research
2017-09-06 • PLOS One
2017-09-06 • PLOS One
Cryptococcal meningitis is one of the leading causes of death among people with HIV in Africa, primarily due to delayed presentation, poor availability and high cost of treatment. Routin...
Journal Article
|Research
2019-08-01 • AIDS
2019-08-01 • AIDS
BACKGROUND
Many individuals failing first-line antiretroviral therapy (ART) in sub-Saharan Africa never initiate second-line ART or do so after significant delay. For people on ART w...
Many individuals failing first-line antiretroviral therapy (ART) in sub-Saharan Africa never initiate second-line ART or do so after significant delay. For people on ART w...
Journal Article
|Research
2018-02-13 • Lancet Infectious Diseases
2018-02-13 • Lancet Infectious Diseases
BACKGROUND
Bedaquiline and delamanid have been approved for treatment of multidrug-resistant (MDR) tuberculosis in the past 5 years. Because of theoretical safety concerns, patients ...
Bedaquiline and delamanid have been approved for treatment of multidrug-resistant (MDR) tuberculosis in the past 5 years. Because of theoretical safety concerns, patients ...
Journal Article
|Research
2019-07-31 • PLOS One
2019-07-31 • PLOS One
BACKGROUND:
Estimates for the prevalence of rape and other forms of sexual violence (SV) vary in South Africa. This survey aimed to provide clarity by quantifying the prevalence of ...
Estimates for the prevalence of rape and other forms of sexual violence (SV) vary in South Africa. This survey aimed to provide clarity by quantifying the prevalence of ...
Journal Article
|Research
2019-05-02 • PLOS One
2019-05-02 • PLOS One
INTRODUCTION:
HIV self-testing (HIVST) offers a useful addition to HIV testing services and enables individuals to test privately. Despite recommendations to the contrary, repeat HIV...
HIV self-testing (HIVST) offers a useful addition to HIV testing services and enables individuals to test privately. Despite recommendations to the contrary, repeat HIV...
Journal Article
|Research
2020-06-01 • International Journal of Infectious Diseases
2020-06-01 • International Journal of Infectious Diseases
BACKGROUND
Cryptococcal Meningitis (CM) is estimated to cause 181,000 deaths annually; with the majority occurring in Sub Saharan Africa. Flucytosine is recommended by the World Heal...
Cryptococcal Meningitis (CM) is estimated to cause 181,000 deaths annually; with the majority occurring in Sub Saharan Africa. Flucytosine is recommended by the World Heal...
Journal Article
|Research
2015-05-11 • HIV/AIDS Research and Treatment Open Journal
2015-05-11 • HIV/AIDS Research and Treatment Open Journal
OBJECTIVES
We conducted a mixed method study to evaluate the pilot of community ART groups (CAG’s) in Lesotho.
METHODS
At the end of 2012 CAGs were piloted in Nazareth c...
We conducted a mixed method study to evaluate the pilot of community ART groups (CAG’s) in Lesotho.
METHODS
At the end of 2012 CAGs were piloted in Nazareth c...
Journal Article
|Research
2017-05-18 • PLOS One
2017-05-18 • PLOS One
BACKGROUND
Daily directly-observed therapy (DOT) is recommended for rifampicin-resistant tuberculosis (RR-TB) patients throughout treatment. We assessed the impact of self-administer...
Daily directly-observed therapy (DOT) is recommended for rifampicin-resistant tuberculosis (RR-TB) patients throughout treatment. We assessed the impact of self-administer...
Journal Article
|Commentary
2018-10-18 • Lancet Infectious Diseases
2018-10-18 • Lancet Infectious Diseases
In 2018, WHO issued guidelines for the diagnosis, prevention, and management of HIV-related cryptococcal disease. Two strategies are recommended to reduce the high mortality associated w...
Journal Article
|Review
2014-01-20 • Journal of the International AIDS Society
2014-01-20 • Journal of the International AIDS Society
Introduction: Point-of-care testing for CD4 cell count is considered a promising way of reducing the time to eligibility assessment for antiretroviral therapy (ART) and of increasing ret...
Journal Article
|Research
2013-06-05 • PLOS One
2013-06-05 • PLOS One
Introduction Mother-to-Mother (M2M) or “Mentor Mother” programmes utilise HIV positive mothers to provide support and advice to HIV positive pregnant women and mothers of HIV exposed bab...
Journal Article
|Research
2019-12-18 • Journal of Infectious Diseases
2019-12-18 • Journal of Infectious Diseases
Abstract
INTRODUCTION:
Oral pre-exposure prophylaxis (PrEP) in the form of tenofovir-disoproxil-fumarate/emtricitabine is being implemented in selected sites in South Africa. A...
INTRODUCTION:
Oral pre-exposure prophylaxis (PrEP) in the form of tenofovir-disoproxil-fumarate/emtricitabine is being implemented in selected sites in South Africa. A...
Journal Article
|Research
2015-12-01 • Nature
2015-12-01 • Nature
There are inefficiencies in current approaches to monitoring patients on antiretroviral therapy in sub-Saharan Africa. Patients typically attend clinics every 1 to 3 months for clinical ...
Journal Article
|Research
2017-07-26 • BMC Infectious Diseases
2017-07-26 • BMC Infectious Diseases
Combined prevention interventions, including early antiretroviral therapy initiation, may substantially reduce HIV incidence in hyperendemic settings. Our aim was to assess the potential...
Journal Article
|Research
2018-05-03 • European Respiratory Journal
2018-05-03 • European Respiratory Journal
Experience with delamanid (Dlm) is limited, particularly among HIV-positive individuals. We describe early efficacy and safety data from a programmatic setting in South Africa. This was ...
Journal Article
|Research
2022-06-21 • Lancet Infectious Diseases
2022-06-21 • Lancet Infectious Diseases
BACKGROUND
Although flucytosine is a key component of WHO-recommended induction treatment for HIV-associated cryptococcal meningitis, this antifungal agent is not widely available in...
Although flucytosine is a key component of WHO-recommended induction treatment for HIV-associated cryptococcal meningitis, this antifungal agent is not widely available in...
Journal Article
|Research
2017-10-01 • International Journal of Tuberculosis and Lung Disease
2017-10-01 • International Journal of Tuberculosis and Lung Disease
OBJECTIVE
To assess the proportion of rifampicin-resistant tuberculosis (RR-TB) patients with potential earlier RR-TB diagnoses in Khayelitsha, South Africa.
DESIGN
We c...
To assess the proportion of rifampicin-resistant tuberculosis (RR-TB) patients with potential earlier RR-TB diagnoses in Khayelitsha, South Africa.
DESIGN
We c...