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3 result(s)
Journal Article > Short ReportFull Text

Spatiotemporal modeling of cholera, Uvira, Democratic Republic of the Congo, 2016−2020

Emerg Infect Dis. 1 August 2024; Volume 30 (Issue 8); 1677-1682.; DOI:10.3201/eid3008.231137
Ratnayake R, Knee J, Cumming O, Saidi JM, Rumedeka BB,  et al.
Emerg Infect Dis. 1 August 2024; Volume 30 (Issue 8); 1677-1682.; DOI:10.3201/eid3008.231137

We evaluated the spatiotemporal clustering of rapid diagnostic test−positive cholera cases in Uvira, eastern Democratic Republic of the Congo. We detected spatiotemporal clusters that consistently overlapped with major rivers, and we outlined the extent of zones of increased risk that are compatible with the radii currently used for targeted interventions.

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Journal Article > ResearchFull Text

Cholera deaths during outbreaks in Uvira, Eastern Democratic Republic of the Congo, 10-35 months after mass vaccination

Open Forum Infect Dis. 1 February 2024; Volume 11 (Issue 3); ofae058.; DOI:10.1093/ofid/ofae058
Bugeme PM, Xu H, Hutchins C, Dent J, Saidi JM,  et al.
Open Forum Infect Dis. 1 February 2024; Volume 11 (Issue 3); ofae058.; DOI:10.1093/ofid/ofae058
Our understanding of the burden and drivers of cholera mortality is hampered by limited surveillance and confirmation capacity. Leveraging enhanced clinical and laboratory surveillance in the cholera-endemic community of Uvira, eastern Democratic Republic of Congo, we describe cholera deaths across 3 epidemics between September 2021 and September 2023 following mass vaccination.More
Journal Article > ResearchFull Text

Genomic microevolution of Vibrio cholerae O1, Lake Tanganyika Basin, Africa

Emerg Infect Dis. 1 January 2023; Volume 29 (Issue 1); 149-153.; DOI:10.3201/eid2901.220641
Hounmanou YM, Njamkepo E, Rauzier J, Gallandat K, Jeandron A,  et al.
Emerg Infect Dis. 1 January 2023; Volume 29 (Issue 1); 149-153.; DOI:10.3201/eid2901.220641
Africa’s Lake Tanganyika basin is a cholera hotspot. During 2001–2020, Vibrio cholerae O1 isolates obtained from the Democratic Republic of the Congo side of the lake belonged to 2 of the 5 clades of the AFR10 sublineage. One clade became predominant after acquiring a parC mutation that decreased susceptibility to ciprofloxacin.More