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Copyright © Médecins Sans Frontières
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Showing 1 - 6 of 6 Items
Showing 1 - 6 of 6 Items
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Journal Article
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Research

Comparative effectiveness of adding delamanid to a multidrug-resistant tuberculosis regimen comprised of three drugs likely to be effective

Rodriguez CA, Lodi S, Horsburgh CR, Mitnick CD, Bastard M,  et al.
2023-04-28 • PLOS Global Public Health
2023-04-28 • PLOS Global Public Health
Clarity about the role of delamanid in longer regimens for multidrug-resistant TB is needed after discordant Phase IIb and Phase III randomized controlled trial results. The Phase IIb tr...
Journal Article
|
Research

Selection bias in multidrug-resistant tuberculosis cohort studies assessing sputum culture conversion

Rodriguez CA, Lodi S, Horsburgh CR, Bastard M, Hewison C,  et al.
2022-11-10 • PLOS One
2022-11-10 • PLOS One

BACKGROUND

Journal Article
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Review

Programmatic management of drug-resistant tuberculosis: an updated research agenda

Mitnick CD, Rodriguez CA, Hatton ML, Brigden G, Cobelens F,  et al.
2016-05-25 • PLOS One
2016-05-25 • PLOS One
INTRODUCTION
There are numerous challenges in delivering appropriate treatment for multidrug-resistant tuberculosis (MDR-TB) and the evidence base to guide those practices remains li...
Journal Article
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Research

Early mortality during rifampicin-resistant TB treatment

Mohr-Holland E, Daniels J, Reuter A, Rodriguez CA, Mitnick CD,  et al.
2022-02-01 • International Journal of Tuberculosis and Lung Disease
2022-02-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
Data suggest that treatment with newer TB drugs (linezolid [LZD], bedaquiline [BDQ] and delamanid [DLM]), used in Khayelitsha, South Africa, since 2012, reduces mortality ...
Journal Article
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Research

Drug-resistant tuberculosis clinical trials: proposed core research definitions in adults

Furin J, Alirol E, Allen E, Fielding K, Merle CS,  et al.
2016-03-01 • International Journal of Tuberculosis and Lung Disease
2016-03-01 • International Journal of Tuberculosis and Lung Disease
Drug-resistant tuberculosis (DR-TB) is a growing public health problem, and for the first time in decades, new drugs for the treatment of this disease have been developed. These new dru...
Journal Article
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Research

Multidrug-Resistant Tuberculosis Treatment Failure Detection Depends on Monitoring Interval and Microbiological Method

Mitnick CD, White RA, Lu C, Rodriguez CA, Bayona J,  et al.
2016-09-01 • European Respiratory Journal
2016-09-01 • European Respiratory Journal
Debate persists about monitoring method (culture or smear) and interval (monthly or less frequently) during treatment for multidrug-resistant tuberculosis (MDR-TB). We analysed existing ...