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Copyright © Médecins Sans Frontières
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Showing 1 - 6 of 6 Items
Showing 1 - 6 of 6 Items
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Journal Article
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Research

Phenotypic and genotypic resistance to bedaquiline in patients with multi-drug-resistant tuberculosis—experiences from Armenia

Ardizzoni E, Mulders W, De Diego Fuertes M, Hayrapetyan A, Mirzoyan A,  et al.
2025-04-09 • Antimicrobial Agents and Chemotherapy
2025-04-09 • Antimicrobial Agents and Chemotherapy

Risk factors for baseline bedaquiline (BDQ) resistance, amplification during treatment, and correlations with treatment outcomes are not fully understood. This cohort included Armenia...

Journal Article
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Letter

Reduced critical concentration might not have improved MGIT-based DST’s sensitivity to rifampicin

Rupasinghe P, Ashraf A, Barreda N, Parveen S, Zubair M,  et al.
2024-05-02 • Antimicrobial Agents and Chemotherapy
2024-05-02 • Antimicrobial Agents and Chemotherapy
Journal Article
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Research

Bedaquiline resistance in patients with drug-resistant tuberculosis in Cape Town, South Africa: a retrospective longitudinal cohort study

Derendinger B, Dippenaar A, de Vos M, Huo S, Alberts R,  et al.
2023-12-01 • Lancet Microbe
2023-12-01 • Lancet Microbe
BACKGROUND
Bedaquiline is a life-saving tuberculosis drug undergoing global scale-up. People at risk of weak tuberculosis drug regimens are a priority for novel drug access despite t...
Journal Article
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Research

Does One Size Fit All? Drug Resistance and Standard Treatments: Results of Six Tuberculosis Programmes in Former Soviet Countries

Bonnet MMB, Sizaire V, Kebede YYK, Janin A, Doshetov D,  et al.
2005-10-01 • International Journal of Tuberculosis and Lung Disease
2005-10-01 • International Journal of Tuberculosis and Lung Disease
SETTING: After the collapse of the Soviet Union, countries in the region faced a dramatic increase in tuberculosis cases and the emergence of drug resistance. OBJECTIVE: To discuss the r...
Journal Article
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Research

Outcomes after chemotherapy with WHO category II regimen in a population with high prevalence of drug resistant tuberculosis

Matthys F, Rigouts L, Sizaire V, Vezhnina N, Lecoq M,  et al.
2009-11-23 • PLOS One
2009-11-23 • PLOS One
Standard short course chemotherapy is recommended by the World Health Organization to control tuberculosis worldwide. However, in settings with high drug resistance, first line standard ...
Journal Article
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Research

The thin-layer agar method for direct phenotypic detection of multi- and extensively drug-resistant tuberculosis

Ardizzoni E, Mulders W, Kotrikadze T, Goginashvili L, Pangtey H,  et al.
2015-12-02 • International Journal of Tuberculosis and Lung Disease
2015-12-02 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
Molecular techniques rapidly detect resistance to rifampicin (RMP) and isoniazid (INH), but do not eliminate the need for culture-based drug susceptibility testing (DST) a...