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Showing 1 - 20 of 54 Items
Showing 1 - 20 of 54 Items
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Journal Article
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Research

Faecal carriage of extended-spectrum ß-lactamase-producing Escherichia coli in a remote region of Niger

Jacquier H, Assao B, Chau F, Guindo O, Condamine B,  et al.
2023-06-25 • Journal of Infection
2023-06-25 • Journal of Infection
OBJECTIVE
Whole genome sequencing (WGS) of extended-spectrum ß-lactamase-producing Escherichia coli (ESBL-E. coli) in developing countries is lacking. Here we describe the population...
Journal Article
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Research

Meningitis Dipstick Rapid Test: Evaluating Diagnostic Performance During an Urban Neisseria Meningitidis Serogroup A Outbreak, Burkina Faso, 2007

Rose AMC, Mueller JE, Gerstl S, Njanpop-Lafourcade BM, Page AL,  et al.
2010-06-11 • PLOS One
2010-06-11 • PLOS One
Meningococcal meningitis outbreaks occur every year during the dry season in the "meningitis belt" of sub-Saharan Africa. Identification of the causative strain is crucial before launchi...
Journal Article
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Research

Evaluation of the Nova StatSensor® XpressTM Creatinine Point-Of-Care Handheld Analyzer

Kosack CS, de Kieviet W, Bayrak K, Milovic A, Page AL
2015-04-17 • PLOS One
2015-04-17 • PLOS One
Creatinine is a parameter that is required to monitor renal function and is important to follow in patients under treatment with potentially toxic renal drugs, such as the anti-HIV drug ...
Journal Article
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Research

Diagnostic and Prognostic Value of Procalcitonin and C-Reactive Protein in Malnourished Children

Page AL, de Rekeneire N, Sayadi S, Aberrane S, Janssens AC,  et al.
2014-01-20 • BMC Pediatrics
2014-01-20 • BMC Pediatrics
Early recognition of bacterial infections is crucial for their proper management, but is particularly difficult in children with severe acute malnutrition (SAM). The objectives of this s...
Journal Article
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Research

TSH-CHECK-1 test: diagnostic accuracy and potential application to initiating treatment for hypothyroidism in patients on anti-tuberculosis drugs

Kosack CS, Page AL, Van Hulsteijn LT, Lentjes EG
2012-03-19 • PLOS One
2012-03-19 • PLOS One
Thyroid-stimulating hormone (TSH) promotes expression of thyroid hormones which are essential for metabolism, growth, and development. Second-line drugs to treat tuberculosis (TB) can ca...
Journal Article
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Research

Low Resistance to First and Second Line Anti-Tuberculosis Drugs among Treatment Naive Pulmonary Tuberculosis Patients in Southwestern Uganda

Orikiriza P, Tibenderana B, Siedner MJ, Mueller YK, Byarugaba F,  et al.
2015-02-06 • PLOS One
2015-02-06 • PLOS One
There are limited data on region-specific drug susceptibility of tuberculosis (TB) in Uganda. We performed resistance testing on specimens collected from treatment-naive patients with pu...
Journal Article
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Research

Use of a Cholera Rapid Diagnostic Test during a Mass Vaccination Campaign in Response to an Epidemic in Guinea, 2012

Martinez-Pino I, Luquero FJ, Sakoba K, Sylla S, Haile M,  et al.
2013-08-15 • PLOS Neglected Tropical Diseases
2013-08-15 • PLOS Neglected Tropical Diseases
During the 2012 cholera outbreak in the Republic of Guinea, the Ministry of Health, supported by Médecins Sans Frontières - Operational Center Geneva, used the oral cholera vaccine Shanc...
Journal Article
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Research

Alternative observational designs to estimate the effectiveness of one dose of oral cholera vaccine in Lusaka, Zambia

Ferreras E, Blake A, Chewe O, Mwaba J, Zulu G,  et al.
2020-03-13 • Epidemiology and Infection
2020-03-13 • Epidemiology and Infection
We conducted a matched case-control (MCC), test-negative case-control (TNCC) and case-cohort study in 2016 in Lusaka, Zambia, following a mass vaccination campaign. Confirmed cholera cas...
Journal Article
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Research

Implementing the Xpert MTB/RIF diagnostic test for tuberculosis and rifampicin resistance: outcomes and lessons learned in 18 countries

Ardizzoni E, Fajardo E, Saranchuk P, Casenghi M, Page AL,  et al.
2015-12-15 • PLOS One
2015-12-15 • PLOS One
BACKGROUND
The Xpert® MTB/RIF (Xpert) is an automated molecular test for simultaneous detection of tuberculosis (TB) and rifampicin resistance, recommended by the World Health Organi...
Journal Article
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Research

Evaluation of the SD Bioline cholera rapid diagnostic test during the 2016 cholera outbreak in Lusaka, Zambia

Mwaba J, Ferreras E, Chizema Kawesha E, Mwimbe D, Tafirenyika F,  et al.
2018-05-31 • Tropical Medicine and International Health
2018-05-31 • Tropical Medicine and International Health
OBJECTIVE
To assess the performance of the SD Bioline Cholera Ag O1/O139 rapid diagnostic test (RDT) compared to a reference standard combining culture and PCR for the diagnosis of c...
Journal Article
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Research

Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012

Page AL, Jusot V, Mamaty AA, Adamou L, Kaplon J,  et al.
2014-04-01 • Emerging Infectious Diseases
2014-04-01 • Emerging Infectious Diseases
Knowledge of rotavirus epidemiology is necessary to make informed decisions about vaccine introduction and to evaluate vaccine impact. During April 2010–March 2012, rotavirus surveillanc...
Journal Article
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Research

Towards More Accurate HIV Testing in Sub-Saharan Africa: a Multi-Site Evaluation of HIV RDTs and Risk Factors For False Positives

Kosack CS, Page AL, Beelaert G, Benson TT, Savane A,  et al.
2017-03-22 • Journal of the International AIDS Society
2017-03-22 • Journal of the International AIDS Society
Although individual HIV rapid diagnostic tests (RDTs) show good performance in evaluations conducted by WHO, reports from several African countries highlight potentially significant perf...
Journal Article
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Commentary

Response to Comment on "Alert, but not Alarmed" - A Comment on "Towards More Accurate HIV Testing in Sub-Saharan Africa: A Multi-Site Evaluation of HIV RDTs and Risk Factors for False Positives (Kosack et al. 2017)"

Kosack CS, Page AL, Beelaert G, Benson TT, Savane A,  et al.
2017-07-19 • Journal of the International AIDS Society
2017-07-19 • Journal of the International AIDS Society
Journal Article
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Research

Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria

Ashley EA, Touabi M, Ahrer M, Hutagalung R, Htun K,  et al.
2009-10-27 • Malaria Journal
2009-10-27 • Malaria Journal
BACKGROUND: In areas where non-falciparum malaria is common rapid diagnostic tests (RDTs) capable of distinguishing malaria species reliably are needed. Such tests are often based on the...
Journal Article
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Research

Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study

Azman AS, Parker LA, Rumunu J, Tadesse F, Grandesso F,  et al.
2016-11-01 • Lancet Global Health
2016-11-01 • Lancet Global Health
BACKGROUND
Oral cholera vaccines represent a new effective tool to fight cholera and are licensed as two-dose regimens with 2-4 weeks between doses. Evidence from previous studies su...
Journal Article
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Research

Massive increase, spread, and exchange of extended spectrum {beta}-lactamase-encoding genes among intestinal Enterobacteriaceae in hospitalized children with severe acute malnutrition in Niger

Woerther PL, Angebault C, Jacquier H, Hugede HC, Janssens AC,  et al.
2011-09-02 • Clinical Infectious Diseases
2011-09-02 • Clinical Infectious Diseases
BACKGROUND
From the time of CTX-M emergence, extended-spectrum β-lactamase-producing enterobacteria (ESBL-E) have spread worldwide in community settings as well as in hospitals, part...
Journal Article
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Research

Prevalence and risk factors of brucellosis among febrile patients attending a community hospital in south western Uganda

Migisha R, Nyehangane D, Page AL, Zuniga-Ripa A, Conde-Alvarez R,  et al.
2018-10-18 • Scientific Reports
2018-10-18 • Scientific Reports
Human brucellosis, a chronic disease contracted through contact with animals and consuption of unpasteurized dairy products is underreported in limited-resource countries. This cross-sec...
Journal Article
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Research

Diagnostic accuracy of VIKIA® Rota-Adeno and Premier™ Rotaclone® tests for the detection of Rotavirus in Niger

Lagare A, Moumouni A, Kaplon J, Langendorf C, Pothier P,  et al.
2017-10-23 • BMC Research Notes
2017-10-23 • BMC Research Notes
We conducted a parallel evaluation of the diagnostic accuracy of VIKIA® Rota-Adeno, a rapid diagnostic test (RDT) and Premier™ Rotaclone® an enzyme immunoassay (EIA) using reverse transc...
Journal Article
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Research

Designing HIV Testing Algorithms Based on 2015 WHO Guidelines Using Data from Six Sites in sub-Saharan Africa

Kosack CS, Shanks L, Beelaert G, Benson TT, Savane A,  et al.
2017-07-26 • Journal of Clinical Microbiology
2017-07-26 • Journal of Clinical Microbiology
Our objective was to evaluate the performance of HIV testing algorithms based on WHO recommendations, using data from specimens collected at six HIV testing and counselling sites in sub-...
Journal Article
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Research

Oral cholera vaccination in hard-to-reach communities, Lake Chilwa, Malawi

Grandesso F, Rafael F, Chipeta S, Alley I, Saussier C,  et al.
2018-09-27 • Bulletin of the World Health Organization
2018-09-27 • Bulletin of the World Health Organization
OBJECTIVE
To evaluate vaccination coverage, identify reasons for non-vaccination and assess satisfaction with two innovative strategies for distributing second doses in an oral chole...