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Copyright © Médecins Sans Frontières
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Showing 1 - 3 of 3 Items
Showing 1 - 3 of 3 Items
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Journal Article
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Research

Switching to second-line antiretroviral therapy in resource-limited settings: comparison of programmes with and without viral load monitoring

Keiser O, Tweya H, Boulle AM, Braitstein P, Schechter M,  et al.
2009-09-10 • AIDS
2009-09-10 • AIDS
BACKGROUND
In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring ...
Journal Article
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Research

Correcting mortality for loss to follow-up: a nomogram applied to antiretroviral treatment programmes in sub-Saharan Africa

Egger M, Sidle J, Weigel R, Geng EH, Fox MP,  et al.
2011-01-01 • PLOS Medicine
2011-01-01 • PLOS Medicine
The World Health Organization estimates that in sub-Saharan Africa about 4 million HIV-infected patients had started antiretroviral therapy (ART) by the end of 2008. Loss of patients to ...
Journal Article
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Research

Selection strength and hitchhiking around two anti-malarial resistance genes

Nash D, Nair SA, Mayxay M, Newton PN, Guthmann JP,  et al.
2005-06-02 • Proceedings. Biological sciences / The Royal Society
2005-06-02 • Proceedings. Biological sciences / The Royal Society
Neutral mutations may hitchhike to high frequency when they are situated close to sites under positive selection, generating local reductions in genetic diversity. This process is though...