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Research

A qualitative exploration of women’s choices and experiences of using oral and vaginal HIV pre-exposure prophylaxis in Eswatini

Mukooza E, Mmema N, Dlamini V, Mabhena E, Daka M,  et al.
2025-12-01 • AIDS Care
2025-12-01 • AIDS Care

Understanding women’s decision-making when offered different HIV pre-exposure prophylaxis (PrEP) options is critical for improving uptake. This qualitative study explored factors infl...

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Predictive risk assessment and targeted testing could enhance STI diagnosis in a high HIV prevalence setting in Eswatini

Kerschberger B, Lekelem S, Ntshalintshali N, Mukooza E, Daka M,  et al.
2025-09-29 • Scientific Reports
2025-09-29 • Scientific Reports

Sexually transmitted infections (STIs) present significant public health challenges in resource-limited set...

Targeted approaches for acute HIV infection diagnosis in rural Eswatini

Ciglenecki I, Kerschberger B, Mukooza E, Lekelem S, Ntshalintshali N,  et al.
2025-09-02 • International Journal of STD and AIDS
2025-09-02 • International Journal of STD and AIDS

INTRODUCTION

Acute HIV infection (AHI) diagnosis is challenging due to complex diagnostics and low&n...

High burden of symptomatic and asymptomatic sexually transmitted infections in a routine decentralised HIV care setting in Eswatini: A cross-sectional study

Kerschberger B, Ntshalintshali N, Mafomisa MI, Mabhena E, Daka M,  et al.
2025-07-22 • Tropical Medicine and International Health
2025-07-22 • Tropical Medicine and International Health

OBJECTIVES

Sexually transmitted infections are a global public health concern. We aimed to assess the burden of a diverse range of sexually transmitted infectio...

Low sensitivity of the fourth‐generation antigen/antibody HIV rapid diagnostic test Determine™ HIV Early Detect for detection of acute HIV infection at the point of care in rural Eswatini: a diagnostic accuracy study

Ciglenecki I, Ntshalintshali N, Mukooza E, Lekelem S, Mavimbela M,  et al.
2025-06-28 • Journal of the International AIDS Society
2025-06-28 • Journal of the International AIDS Society

INTRODUCTION

The diagnosis of acute HIV infection (AHI) is challenging in routine settings because it cannot be detected by routine third‐generation antibody ra...

Mycoplasma genitalium infection in Eswatini amid syndromic case management: Prevalence, coinfections, diagnostic challenges and treatment gaps

Kerschberger B, Lekelem S, Daka M, Ntshalintshali N, Mabhena E,  et al.
2025-04-17 • BMC Infectious Diseases
2025-04-17 • BMC Infectious Diseases

BACKGROUND

The global epidemic of Mycoplasma genitalium (MG) is marked by its widespread prevalence, varied resistance patterns, and significant impact on sexua...

Drivers of HIV pre-exposure prophylaxis choice among women in Eswatini

Mukooza E, Mmema N, Dlamini V, Dlamini SV, Mafomisa M,  et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024

High burden of sexually transmitted infections and poor diagnostic performance of syndromic approaches within a decentralized HIV care setting in Eswatini

Kerschberger B, Mukooza E, Berto A, Ntshalintshali N, Mafomisa M,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023

High burden of sexually transmitted infections and poor diagnostic performance of syndromic approaches within a decentralised HIV care setting in Eswatini

Kerschberger B, Ntshalintshali N, Mafomisa M, Mabhena E, Daka M,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
INTRODUCTION
Sexually transmitted infections (STI’s) are a public health threat. Syndromic approaches based on clinical symptoms have been suggested as having poor diagnostic perform...

PrEP reminds me that I am the one to take responsibility of my life: a qualitative study exploring experiences of and attitudes towards pre-exposure prophylaxis use by women in Eswatini

Bjertrup PJ, Mmema N, Dlamini V, Ciglenecki I, Mpala Q,  et al.
2021-04-14 • BMC Public Health
2021-04-14 • BMC Public Health
BACKGROUND
Pre-exposure-prophylaxis (PrEP) has been heralded for its potential to put women in control of preventing HIV infection, but uptake and continuation rates have been disapp...

Kidney function in tenofovir disoproxil fumarate-based oral pre-exposure prophylaxis users: a systematic review and meta-analysis of published literature and a multi-country meta-analysis of individual participant data

Schaefer R, Amparo da Costa Leite PH, Silva R, Abdool Karim Q, Akolo C,  et al.
2022-03-07 • Lancet HIV
2022-03-07 • Lancet HIV
BACKGROUND
Previous WHO guidance on tenofovir disoproxil fumarate-based oral pre-exposure prophylaxis (PrEP) suggests measuring creatinine levels at PrEP initiation and regularly aft...