Search Results | MSF Science Portal

Journal Article

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Commentary

Vonasek BJ, Marcy O, Armour J, Casenghi M, Cazes C, et al.

2025-03-23 • Lancet Child and Adolescent Health

Each day more than 500 children younger than 15 years die from tuberculosis. Considerable progress has been...

Journal Article

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Research

Melingui BF, Basant J, Taguebue Jv, Massom DM, Leroy Terquem E, et al.

2024-11-03 • Journal of Tropical Medicine

OBJECTIVES

Chest x‐ray (CXR) plays an important role in childhood tuberculosis (TB) diagnosis, but access to quality CXR remains a major challenge in resource‐l...

Journal Article

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Research

d’Elbée M, Harker M, Mafirakureva N, Nanfuka M, Nguyet MHTN, et al.

2024-03-21 • eClinicalMedicine

Journal Article

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Research

Wobudeya E, Nanfuka M, Ton Nu Nguyet MH, Taguebue JV, Moh R, et al.

2024-03-21 • ACG Case Reports Journal

BACKGROUND
Childhood tuberculosis (TB) remains underdiagnosed largely because of limited awareness and poor access to all or any of specimen collection, molecular testing, clinical e...

Journal Article

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Research

Melingui BF, Leroy-Terquem E, Palmer M, Taguebue JV, Wachinou AP, et al.

2024-02-01 • IJTLD OPEN

BACKGROUND
Chest X-ray (CXR) interpretation is challenging for the diagnosis of paediatric TB. We assessed the performance of a three half-day CXR training module for healthcare work...

Journal Article

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Research

Pean P, Madec Y, Nerrienet E, Borand L, Laureillard D, et al.

2023-10-13 • Pathogens

IRIS is a common complication in HIV-infected patients treated for tuberculosis (TB) and cART. Our aim was to evaluate NK cell reconstitution in HIV-infected patients with TB-IRIS compar...

Journal Article

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Research

Joshi B, De Lima YV, Massom DM, Kaing S, Banga MF, et al.

2023-10-11 • PLOS Global Public Health

Decentralizing childhood tuberculosis services, including diagnosis, is now recommended by the WHO and could contribute to increasing tuberculosis detection in high burden countries. How...

Journal Article

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Research

Gunasekera KS, Marcy O, Muñoz J, Lopez-Varela E, Sekadde MP, et al.

2023-03-13 • Lancet Child and Adolescent Health

BACKGROUND
Many children with pulmonary tuberculosis remain undiagnosed and untreated with related high morbidity and mortality. Recent advances in childhood tuberculosis algorithm d...

Journal Article

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Research

Marcy O, Wobudeya E, Font H, Vessière A, Chabala C, et al.

2023-03-01 • Lancet Infectious Diseases

BACKGROUND
Tuberculosis diagnosis might be delayed or missed in children with severe pneumonia because this diagnosis is usually only considered in cases of prolonged symptoms or ant...

Journal Article

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Research

Laureillard D, Marcy O, Madec Y, Chea S, Chan S, et al.

2013-10-23 • AIDS

To analyze cases of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) in the CAMbodian Early versus Late Introduction of Antiretrovirals (CAMELIA)...

Journal Article

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Research

Blanc FX, Sok T, Laureillard D, Borand L, Rekacewicz C, et al.

2011-10-20 • New England Journal of Medicine

Tuberculosis remains an important cause of death among patients infected with the human immunodeficiency virus (HIV). Robust data are lacking with regard to the timing for the initiation...

Journal Article

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Commentary

Godreuil S, Marcy O, Wobudeya E, Bonnet MMB, Solassol J

2018-03-23 • Lancet Public Health

Journal Article

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Research

Marcy O, Laureillard D, Madec Y, Chan S, Mayaud C, et al.

2014-08-01 • Clinical Infectious Diseases

Shortening the interval between antituberculosis treatment onset and initiation of antiretroviral therapy (ART) reduces mortality in severely immunocompromised human immunodeficiency vir...

Journal Article

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Research

Joshi B, Font H, Wobudeya E, Nanfuka M, Kobusingye A, et al.

2022-03-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
Increasing childhood TB case detection requires the deployment of diagnostic services at peripheral healthcare level. Capacity and readiness of healthcare workers (HCWs) a...

Journal Article

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Research

Borand L, Madec Y, Laureillard D, Chou M, Marcy O, et al.

2014-03-07 • PLOS One

OBJECTIVE
To assess efavirenz plasma concentrations and their association with treatment efficacy and tolerance of efavirenz 600 mg daily in HIV-tuberculosis co-infected patients.

Journal Article

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Research

Pean P, Nouhin J, Ratana M, Madec Y, Borand L, et al.

2019-08-27 • Frontiers in Immunology

Background: Human Immunodeficiency Virus 1 (HIV-1) and Mycobacterium Tuberculosis (Mtb) co-infected patients are commonly at risk of immune reconstitution inflammatory syndrome (IRIS) wh...

Science Portal

Leveraging nutritional rehabilitation and tuberculosis programmes to tackle tuberculosis and severe acute malnutrition in children

Implementation of digital chest radiography for childhood tuberculosis diagnosis at district hospital level in six high tuberculosis burden and resources limited countries

Cost-effectiveness and budget impact of decentralising childhood tuberculosis diagnosis in six high tuberculosis incidence countries: a mathematical modelling study

Effect of decentralising childhood tuberculosis diagnosis to primary health centre versus district hospital levels on disease detection in children from six high tuberculosis incidence countries: an operational research, pre-post intervention study

Evaluation of a short training course of chest X-ray interpretation for the diagnosis of paediatric TB

Natural killer repertoire restoration in TB/HIV co-infected individuals experienced an immune reconstitution syndrome (CAMELIA Trial, ANRS 12153)

Acceptability of decentralizing childhood tuberculosis diagnosis in low-income countries with high tuberculosis incidence: Experiences and perceptions from health care workers in Sub-Saharan Africa and South-East Asia

Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis

Effect of systematic tuberculosis detection on mortality in young children with severe pneumonia in countries with high incidence of tuberculosis: a stepped-wedge cluster-randomised trial

Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome after early initiation of antiretroviral therapy in a randomized clinical trial

Earlier versus later start of antiretroviral therapy in HIV-infected adults with tuberculosis

Tackling mortality due to childhood tuberculosis

Causes and determinants of mortality in HIV-infected adults with tuberculosis: an analysis from the CAMELIA ANRS 1295-CIPRA KH001 randomized trial

Knowledge, attitudes and practices on childhood TB among healthcare workers

Plasma concentrations, efficacy and safety of efavirenz in HIV-infected adults treated for tuberculosis in Cambodia (ANRS 1295-CIPRA KH001 CAMELIA trial)

High Activation of γδ T Cells and the γδ2 T-Cell Subset Is Associated With the Onset of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome, ANRS 12153 CAPRI NK.