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Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 10 of 10 Items
Showing 1 - 10 of 10 Items
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Journal Article
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Research

MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era

Beckert P, Sanchez-Padilla E, Merker M, Dreyer V, Kohl TA,  et al.
2020-11-25 • Genome Medicine
2020-11-25 • Genome Medicine
Background
Multidrug-resistant (MDR) Mycobacterium tuberculosis complex strains not detected by commercial molecular drug susceptibility testing (mDST) assays due to the RpoB I491F ...
Journal Article
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Research

Field suitability and diagnostic accuracy of the Biocentric open real-time PCR platform for plasma-based HIV viral load quantification in Swaziland

Mpala Q, Maphalala G, Uribe PAD, de la Tour R, Kalombola S,  et al.
2018-11-14 • BMC Infectious Diseases
2018-11-14 • BMC Infectious Diseases
Viral load (VL) testing is being scaled up in resource-limited settings. However, not all commercially available VL testing methods have been evaluated under field conditions. This study...
Journal Article
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Research

Field suitability and diagnostic accuracy of the Biocentric open real-time PCR platform for dried blood spot-based HIV viral load quantification in Eswatini

Kerschberger B, Ntshalintshali N, Mpala Q, Diaz Uribe PA, Maphalala G,  et al.
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND
To assess the performance and suitability of dried blood spot (DBS) sampling using filter paper to collect blood for viral load (VL) quantification under routine condition...
Journal Article
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Research

Successes and challenges in optimizing the viral load cascade to improve antiretroviral therapy adherence and rationalize second-line switches in Swaziland

Etoori D, Ciglenecki I, Ndlangamandla M, Edwards CG, Jobanputra K,  et al.
2018-10-21 • Journal of the International AIDS Society
2018-10-21 • Journal of the International AIDS Society
As antiretroviral therapy (ART) is scaled up, more patients become eligible for routine viral load (VL) monitoring, the most important tool for monitoring ART efficacy. For HIV programme...
Conference Material
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Abstract

Diagnostic performance of lateral flow point-of-care HIV-Combo testing for detection of acute HIV infection in Eswatini

Kerschberger B, Ntshalintshali N, Maphalala G, Aung A, Mamba C,  et al.
2021-05-19 • MSF Scientific Days International 2021: Research
2021-05-19 • MSF Scientific Days International 2021: Research
INTRODUCTION
Acute HIV infection (AHI) is rarely diagnosed in resource-limited settings. Barriers to diagnosis include the high costs of viral load (VL)-based diagnostic testing algo...
Conference Material
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Abstract

Diagnosing and treating cases of acute HIV infection within a high HIV incidence setting: feasibility study, Eswatini

Aung A, Mamba C, Ntshalintshali N, Mpala Q, Mthethwa-Hleza S,  et al.
2020-05-26 • MSF Scientific Days International 2020: Research
2020-05-26 • MSF Scientific Days International 2020: Research
INTRODUCTION
Acute HIV infection (AHI) cannot be detected with routine point-of-care antibody tests and is rarely diagnosed in resource-limited settings. However, characteristics of ...
Conference Material
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Poster

Establishment of a predictor risk score for the prioritization of patients for testing for acute HIV infection

Kerschberger B, Mpala Q, Aung A, Ntshalintshali N, Mamba C,  et al.
2021-05-18 • MSF Scientific Days International 2021: Research
2021-05-18 • MSF Scientific Days International 2021: Research
Journal Article
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Research

Countrywide roll-out of Xpert® MTB/RIF in Swaziland: the first three years of implementation

Sikhondze W, Dlamini T, Khumalo D, Maphalala G, Dlamini SV,  et al.
2015-06-21 • Public Health Action
2015-06-21 • Public Health Action
SETTING
All 19 public health laboratories in Swaziland that had Xpert(®) MTB/RIF machines installed as part of a countrywide roll-out between June 2011 and June 2014.

OBJECT...
Journal Article
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Research

Predicting, diagnosing, and treating acute and early HIV infection in a public sector facility in Eswatini

Kerschberger B, Aung A, Mpala Q, Ntshalintshali N, Mamba C,  et al.
2021-12-15 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
2021-12-15 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
BACKGROUND
The lack of acute and early HIV infection (AEHI) diagnosis and care contributes to high HIV incidence in resource-limited settings. We aimed to assess the yield, predict a...
Conference Material
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Slide Presentation

Diagnostic performance of lateral flow point-of-care HIV-Combo testing for detection of acute HIV infection in Eswatini

Kerschberger B, Ntshalintshali N, Maphalala G, Aung A, Mamba C,  et al.
2021-05-19 • MSF Scientific Days International 2021: Research
2021-05-19 • MSF Scientific Days International 2021: Research