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Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 20 of 38 Items
Showing 1 - 20 of 38 Items
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Journal Article
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Research

Changes over time in the proportion of advanced HIV disease in two high HIV prevalence settings in Ndhiwa (Kenya) and Eshowe (South Africa)

Chihana M, Conan N, Ohler L, Huerga H, Wanjala S,  et al.
2024-06-17 • Journal of the International Association of Providers of AIDS Care
2024-06-17 • Journal of the International Association of Providers of AIDS Care
BACKGROUND
The burden of advanced HIV disease remains a significant concern in sub-Saharan Africa. In 2015, the World Health Organization released recommendations to treat all people...
Journal Article
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Research

Adolescents and young adults are the most undiagnosed of HIV and virally unsuppressed in Eastern and Southern Africa: Pooled analyses from five population-based surveys

Huerga H, Farhat JB, Maman D, Conan N, Van Cutsem G,  et al.
2023-12-22 • PLOS Global Public Health
2023-12-22 • PLOS Global Public Health
Age and gender disparities within the HIV cascade of care are critical to focus interventions efficiently. We assessed gender-age groups at the highest probability of unfavorable outcome...
Journal Article
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Research

Potential Impact of Multiple Interventions on HIV Incidence in a Hyperendemic Region in Western Kenya: a Modelling Study

Blaizot S, Maman D, Riche B, Mukui I, Kirubi B,  et al.
2016-04-29 • BMC Infectious Diseases
2016-04-29 • BMC Infectious Diseases
Multiple prevention interventions, including early antiretroviral therapy initiation, may reduce HIV incidence in hyperendemic settings. Our aim was to predict the short-term impact of v...
Journal Article
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Research

Extremely Low Hepatitis C prevalence among HIV co-infected individuals in 4 countries in sub-Saharan Africa

Loarec A, Carnimeo V, Molfino L, Kizito W, Muyindike WR,  et al.
2018-11-16 • AIDS
2018-11-16 • AIDS
: A multicentric, retrospective case-series analysis (facility-based) in five sites across Kenya, Malawi, Mozambique, and Uganda screened HIV-positive adults for hepatitis C virus (HCV) ...
Journal Article
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Research

Voluntary Community Human Immunodeficiency Virus Testing, Linkage, and Retention in Care Interventions in Kenya: Modeling the Clinical Impact and Cost-effectiveness

Luong Nguyen LB, Yazdanpanah Y, Maman D, Wanjala S, Vandenbulcke A,  et al.
2018-05-08 • Clinical Infectious Diseases
2018-05-08 • Clinical Infectious Diseases
In southwest Kenya, the prevalence of human immunodeficiency virus (HIV) infection is about 25%. Médecins Sans Frontières has implemented a voluntary community testing (VCT) program, wit...
Journal Article
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Research

Field Evaluation of Near Point of Care Cepheid GeneXpert HIV-1 Qual for Early Infant Diagnosis

Opollo VS, Nikuze A, Ben Farhat J, Anyango E, Humwa F,  et al.
2018-12-27 • PLOS One
2018-12-27 • PLOS One
Access to point-of-care HIV testing shortens turn-around times, time to diagnosis and reduces loss to follow-up hence minimizing barriers to early linkage to care and treatment among HIV...
Journal Article
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Research

Simplifying switch to second-line antiretroviral therapy in sub Saharan Africa: predicted effect of using a single viral load to define efavirenz-based first-line failure

Shroufi A, van Cutsem G, Cambiano V, Bansi-Matharu L, Duncan K,  et al.
2019-08-01 • AIDS
2019-08-01 • AIDS
BACKGROUND
Many individuals failing first-line antiretroviral therapy (ART) in sub-Saharan Africa never initiate second-line ART or do so after significant delay. For people on ART w...
Journal Article
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Research

Errors generated by a point-of-care CD4+ T-lymphocyte analyser: a retrospective observational study in nine countries

Fajardo E, Metcalf CJ, Piriou E, Gueguen M, Maman D,  et al.
2015-06-25 • Bulletin of the World Health Organization
2015-06-25 • Bulletin of the World Health Organization
OBJECTIVE
To estimate the proportion of invalid results generated by a CD4+ T-lymphocyte analyser used by Médecins Sans Frontières (MSF) in field projects and identify factors associ...
Journal Article
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Research

Cost and cost-effectiveness of a simplified treatment model with direct-acting antivirals for chronic hepatitis C in Cambodia

Walker JG, Mafirakureva N, Iwamoto M, Campbell L, Kim CS,  et al.
2020-05-31 • Liver International
2020-05-31 • Liver International
BACKGROUND & AIMS
In 2016, Médecins Sans Frontières established the first general population Hepatitis C virus (HCV) screening and treatment site in Cambodia, offering free direct-ac...
Conference Material
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Poster

Levels of pre-treatment HIV drug resistance in rural and urban settings, Mozambique

Carnimeo V, Fuentes S J, Pulido Tarquino IA, Vaz D, Molfino L,  et al.
2019-05-20 • MSF Scientific Days International 2019: Research
2019-05-20 • MSF Scientific Days International 2019: Research
Journal Article
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Research

Molecular epidemiology of hepatitis C virus in Cambodia during 2016–2017

Nouhin J, Iwamoto M, Prak S, Doussett JP, Phon K,  et al.
2019-05-13 • Scientific Reports
2019-05-13 • Scientific Reports
In Cambodia, little epidemiological data of hepatitis C virus (HCV) is available. All previous studies were limited to only small or specific populations. In the present study, we perfor...
Journal Article
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Short Report

High prevalence of NRTI and NNRTI drug resistance among ART-experienced, hospitalized inpatients

Bossard C, Schramm B, Wanjala S, Jain L, Mucinya G,  et al.
2021-04-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2021-04-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
Journal Article
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Research

Closer to 90-90-90. The Cascade of Care After 10 Years of ART Scale-Up in Rural Malawi: a Population Study

Maman D, Chilima B, Masiku C, Ayouba A, Masson S,  et al.
2016-02-15 • Journal of the International AIDS Society
2016-02-15 • Journal of the International AIDS Society
The antiretroviral therapy (ART) programme supported by Médecins Sans Frontières in the rural Malawian district of Chiradzulu was one of the first in sub-Saharan Africa to scale up ART d...
Journal Article
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Research

Comparative Effectiveness of Interventions to Improve the HIV Continuum of Care and HIV Preexposure Prophylaxis in Kenya: A Model-Based Analysis

Luong Nguyen LB, Freedberg KA, Wanjala S, Maman D, Szumilin E,  et al.
2020-10-27 • Journal of Infectious Diseases
2020-10-27 • Journal of Infectious Diseases
Background
In Western Kenya up to one-quarter of the adult population was human immunodeficiency virus (HIV)-infected in 2012. The Ministry of Health, Médecins Sans Frontières, and ...
Journal Article
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Research

Hepatitis C viraemic and seroprevalence and risk factors for positivity in Northwest Cambodia: a household cross-sectional serosurvey

Lynch E, Falq G, Sun C, Bunchhoeung PDT, Huerga H,  et al.
2021-02-26 • BMC Infectious Diseases
2021-02-26 • BMC Infectious Diseases
BACKGROUND
Despite a dramatic reduction in HCV drug costs and simplified models of care, many countries lack important information on prevalence and risk factors to structure effecti...
Journal Article
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Research

An intensive model of care for hepatitis C virus screening and treatment with direct-acting antivirals in people who inject drugs in Nairobi, Kenya: a model-based cost-effectiveness analysis

Mafirakureva N, Stone J, Fraser H, Nzomukunda Y, Maina A,  et al.
2020-06-29 • Society
2020-06-29 • Society
BACKGROUND AND AIMS
Hepatitis C virus (HCV) treatment is essential for eliminating HCV in people who inject drugs (PWID), but has limited coverage in resource-limited settings. We me...
Protocol
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Research Protocol

Field evaluation of the performance of HCV Serological Rapid Diagnostic Tests among HCV/HIV co-infected patients

Gupta E, Carnimeo V, Samukcham I, Loarec A, Mahajan S,  et al.
2018-07-01
2018-07-01
P R O T O C O L S U M M A R Y
 Title: Field evaluation of the performance of HCV Serological Rapid Diagnostic Tests among
HCV/HIV co-infected patients.
 Aim: To evaluate...
Journal Article
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Research

Estimating HIV incidence using a cross-sectional survey: comparison of three approaches in a hyperendemic setting, Ndhiwa sub-county, Kenya, 2012

Blaizot S, Kim AA, Zeh C, Riche B, Maman D,  et al.
2016-11-08 • AIDS Research and Human Retroviruses
2016-11-08 • AIDS Research and Human Retroviruses
OBJECTIVES
Estimating HIV incidence is critical for identifying groups at risk for HIV infection, planning and targeting interventions, and evaluating these interventions over time. ...
Journal Article
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Research

High Proportions of Patients With Advanced HIV Are Antiretroviral Therapy Experienced: Hospitalization Outcomes From 2 Sub-Saharan African Sites

Ousley J, Niyibizi AA, Wanjala S, Vandenbulcke A, Kirubi B,  et al.
2018-03-04 • Clinical Infectious Diseases
2018-03-04 • Clinical Infectious Diseases
Human immunodeficiency virus (HIV) remains an important cause of hospitalization and death in low- and middle- income countries. Yet morbidity and in-hospital mortality patterns remain p...
Journal Article
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Research

Demonstration of the diagnostic agreement of capillary and venous blood samples, using hepatitis-C virus SD Bioline © rapid test: A clinic-based study

Sun C, Iwamoto M, Calzia A, Sreng B, Yann S,  et al.
2019-02-01 • Journal of Clinical Virology
2019-02-01 • Journal of Clinical Virology
BACKGROUND
Simplifying hepatitis C virus (HCV) screening is a key step in achieving the elimination of HCV as a global public health threat by 2030.

OBJECTIVES
The objec...