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Copyright © Médecins Sans Frontières
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Showing 1 - 5 of 5 Items
Showing 1 - 5 of 5 Items
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Journal Article
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Research

Intravenous rehydration for severe acute malnutrition with gastroenteritis

Maitland K, Ouattara SM, Sainna H, Chara A, Ogundipe OF,  et al.
2025-06-13 • New England Journal of Medicine
2025-06-13 • New England Journal of Medicine

BACKGROUND

International recommendations advise against the use of intravenous rehydration therapy in children with severe acute malnutrition because of the con...

Journal Article
|
Protocol

Gastroenteritis rehydration of children with severe acute malnutrition (GASTROSAM): A phase II randomised controlled trial: Trial protocol

Olupot-Olupot P, Aloroker F, Mpoya A, Mnjalla H, Paasi G,  et al.
2024-01-16 • Wellcome Open Research
2024-01-16 • Wellcome Open Research

BACKGROUND

Chi...

Journal Article
|
Research

Myocardial and haemodynamic responses to two fluid regimens in African children with severe malnutrition and hypovolaemic shock (AFRIM study)

Obonyo N, Brent B, Olupot-Olupot P, Boele van Hensbroek M, Kuipers I,  et al.
2017-05-03 • Critical Care
2017-05-03 • Critical Care
BACKGROUND
Fluid therapy in severely malnourished children is hypothesized to be deleterious owing to compromised cardiac function. We evaluated World Health Organization (WHO) fluid...
Journal Article
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Research

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A,  et al.
2010-11-08 • Lancet
2010-11-08 • Lancet
Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice...
Journal Article
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Research

Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa

Taylor WRJ, Naw HK, Maitland K, Williams TN, Kapulu M,  et al.
2018-01-18 • BMC Medicine
2018-01-18 • BMC Medicine
In 2012, the World Health Organization recommended blocking the transmission of Plasmodium falciparum with single low-dose primaquine (SLDPQ, target dose 0.25 mg base/kg body weight), wi...