Search Results | MSF Science Portal

Journal Article

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Research

Singla R, Khan S, Silsarma A, Chavan V, Mahajan R, et al.

2025-03-13 • Clinical Infectious Diseases

BACKGROUND

Bedaquiline (BDQ) resistance presents a critical challenge in the fight against tuberculosis (TB), particularly multidrug-resistant (MDR) strains. Th...

Journal Article

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Research

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Anh DTV, et al.

2025-02-05 • medRxiv

BACKGROUND

Circulating markers of immune and endothelial activation risk stratify infection syndromes agnostic to disease aetiology. However, their utility in c...

Journal Article

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Letter

Chavan V, Silsarma A, Mahajan R, Khan S, Singh P, et al.

2025-02-01 • IJTLD OPEN

Conference Material

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Poster

Kumar V, Murali S, Goldberg J, Alonso B, Moretó-Planas L, et al.

2024-11-08 • MSF Scientific Days Asia 2024

Conference Material

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Poster

Chavan V, Silsarma A, Khan S, Singh P, Iyer A, et al.

2024-11-08 • MSF Scientific Days Asia 2024

Journal Article

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Research

Khan S, Silsarma A, Mahajan R, Davuluri P, Sutar N, et al.

2024-10-12 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases

BACKGROUND

Tub...

Conference Material

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Poster

Niykayo LF, Mahajan R, Sagrado MJ, Ajack YBP, Chol BT, et al.

2024-05-03 • MSF Paediatric Days 2024

Conference Material

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Video

Fidelle L, Mahajan R, Gallo J, Biague E, Goncalves R, et al.

2024-05-03 • MSF Paediatric Days 2024

Conference Material

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Abstract

Fidelle L, Mahajan R, Gallo J, Biague E, Goncalves R, et al.

2024-05-03 • MSF Paediatric Days 2024

BACKGROUND AND OBJECTIVES
Over half of childhood tuberculosis (TB) remains undiagnosed yearly. TB culture is often unavailable. WHO recommends Xpert-Ultra as first test for diagnosis...

Conference Material

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Slide Presentation

Fidelle L, Mahajan R, Gallo J, Biague E, Goncalves R, et al.

2024-05-03 • MSF Paediatric Days 2024

Journal Article

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Research

Moretó-Planas L, Mahajan R, Fidelle Nyikayo L, Ajack YBP, Tut Chol B, et al.

2024-05-02 • Open Forum Infectious Diseases

BACKGROUND
Over half of childhood tuberculosis (TB) remains undiagnosed yearly. WHO recommends Xpert-Ultra as a first paediatric diagnosis test, but microbiological confirmation rema...

Journal Article

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Research

Mongia H, Mamnoon F, Silsarma A, Mahajan R, Dalal A, et al.

2024-04-01 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases

BACKGROUND
World Health Organization suggests concurrent bedaquiline-delamanid (BDQ-DLM) as part of individualised regimens for eligible patients with pulmonary drug-resistant tuberc...

Journal Article

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Research

Kumar V, Murali S, Goldberg J, Alonso B, Moretó-Planas L, et al.

2024-01-02 • JAC-Antimicrobial Resistance

OBJECTIVES
To describe the prevalence of common bacterial pathogens and antibiotic susceptibility patterns amongst advanced HIV disease (AHD) patients admitted between May 2019 and M...

Journal Article

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Research

Chandna A, Mahajan R, Gautam P, Mwandigha L, Dittrich S, et al.

2023-08-21 • PLOS Global Public Health

The soluble urokinase plasminogen activator receptor (suPAR) has been proposed as a biomarker for risk stratification of patients presenting with acute infections. However, most studies ...

Journal Article

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Letter

Vengurlekar D, Walker C, Mahajan R, Dalal A, Chavan VV, et al.

2023-07-01 • International Journal of Tuberculosis and Lung Disease

Conference Material

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Poster

Moreto-Planas L, Mahajan R, Sagrado MJ, Flevaud L, Gallo J, et al.

2023-06-07 • MSF Scientific Day International 2023

Journal Article

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Research

Moretó-Planas L, Sagrado MJ, Mahajan R, Gallo J, Biague E, et al.

2023-05-19 • BMJ Open

OBJECTIVE
Description of tuberculosis (TB)-focused point-of-care ultrasound (POCUS) findings for children with presumptive TB.

DESIGN
Cross-sectional study (July 2019 to...

Journal Article

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Research

Burza S, Mahajan R, Kazmi S, Alexander N, Kumar D, et al.

2022-10-15 • Clinical Infectious Diseases

BACKGROUND
Visceral leishmaniasis (VL) in patients living with Human-Immunodeficiency-Virus (HIV) present an increasingly important patient cohort in areas where both infections are ...

Journal Article

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Research

Mahajan R, Owen SI, Kumar S, Pandey K, Kazmi S, et al.

2022-08-30 • PLOS Neglected Tropical Diseases

People living with HIV (PLHIV) have an increased risk of developing visceral leishmaniasis (VL) and poor outcomes compared to HIV negative individuals. Here, we aim to establish the prev...

Conference Material

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Abstract

Chandna A, PRIORITISE Study Group, Mahajan R, Gautam P, Mwandigha L, et al.

2022-05-09 • MSF Scientific Days International 2022

INTRODUCTION
In locations where few people have received Covid-19 vaccines, health systems remain vulnerable to spikes in SARS-CoV-2 infections. Triage tools, which could include bio...

Science Portal

Bedaquiline resistance and treatment outcomes among patients with tuberculosis previously exposed to bedaquiline in India: A multicentric retrospective cohort study

Risk stratification of childhood infection using host markers of immune and endothelial activation: A multi-country prospective cohort study in Asia (Spot Sepsis)

Sustained treatment success at 12 months for drug-resistant TB patients on concomitant bedaquiline-delamanid

Antibiotic susceptibility patterns of bacterial pathogens isolated from hospitalized patients with advanced HIV disease (AHD) in Bihar, India

12-month post-treatment outcomes of previously treated drug-resistant tuberculosis patients subsequently treated with concomitant bedaquiline and delamanid +/-carbapenem, in Mumbai, India

Treatment outcomes among patients with isoniazid mono-resistant tuberculosis in Mumbai, India: A retrospective cohort study

Blinded point-of-care ultrasound to support tuberculosis diagnosis in children: a Médecins Sans Frontières cross-sectional study in Malakal, South Sudan

Xpert Ultra in stools and urine for the diagnosis of tuberculosis in children living with HIV: Médecins Sans Frontières experience in Guinea-Bissau and South Sudan

Xpert Ultra in stools and urine for the diagnosis of tuberculosis in children living with HIV: Médecins sans Frontières experience in Guinea-Bissau and South Sudan

Xpert Ultra in stools and urine for the diagnosis of tuberculosis in children living with HIV: Médecins Sans Frontières experience in Guinea-Bissau and South Sudan

Xpert-Ultra assay on stool and urine to improve tuberculosis diagnosis in children: the Médecins Sans Frontières experience in Guinea-Bissau and South Sudan

Concomitant bedaquiline and delamanid therapy in patients with drug-resistant extra-pulmonary tuberculosis in Mumbai, India

Antibiotic susceptibility patterns of pathogens isolated from hospitalized patients with advanced HIV disease (AHD) in Bihar, India

Point-of-care prognostication in moderate Covid-19: Analytical validation and prognostic accuracy of a soluble urokinase plasminogen activator receptor (suPAR) rapid test

Linezolid resistance in patients with drug-resistant TB

Innovative laboratory tools to improve tuberculosis diagnosis in children

Point-of-care ultrasound for tuberculosis diagnosis in children: a Médecins Sans Frontières cross-sectional study in Guinea-Bissau

AmBisome monotherapy and combination AmBisome - miltefosine therapy for the treatment of visceral leishmaniasis in patients co-infected with HIV in India: a randomised open label, parallel arm, phase 3 trial

Prevalence and determinants of asymptomatic Leishmania infection in HIV-infected individuals living within visceral leishmaniasis endemic areas of Bihar, India

Facilitating safe discharge through predicting disease progression in moderate COVID-19: development and validation of a prediction model in resource-limited settings