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Showing 1 - 20 of 57 Items
Showing 1 - 20 of 57 Items
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Journal Article
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Research

Risk stratification of childhood infection using host markers of immune and endothelial activation in Asia (Spot Sepsis): a multi-country, prospective, cohort study

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Van Anh DT,  et al.
2025-09-01 • Lancet Child and Adolescent Health
2025-09-01 • Lancet Child and Adolescent Health

BACKGROUND

Prognostic tools for febrile illnesses are urgently required in resource-constrained community contexts. Circulating immune and endothelial activatio...

Journal Article
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Research

Bedaquiline resistance and treatment outcomes among patients with tuberculosis previously exposed to bedaquiline in India: A multicentric retrospective cohort study

Singla R, Khan S, Silsarma A, Chavan V, Mahajan R,  et al.
2025-03-13 • Clinical Infectious Diseases
2025-03-13 • Clinical Infectious Diseases

BACKGROUND

Bedaquiline (BDQ) resistance presents a critical challenge in the fight against tuberculosis (TB), particularly multidrug-resistant (MDR) strains. Th...

Conference Material
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Abstract

Derivation and validation of prognostic models for the risk stratification of childhood infection: a multi-country prospective cohort study in Asia (Spot-Sepsis)

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Anh DTV,  et al.
2025-02-05 • MSF Scientific Days International 2025
2025-02-05 • MSF Scientific Days International 2025
Conference Material
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Slide Presentation

Derivation and validation of prognostic models for the risk stratification of childhood infection: a multi-country prospective cohort study in Asia (Spot-Sepsis)

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Anh DTV,  et al.
2025-02-05 • MSF Scientific Days International 2025
2025-02-05 • MSF Scientific Days International 2025
Journal Article
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Research

Risk stratification of childhood infection using host markers of immune and endothelial activation: A multi-country prospective cohort study in Asia (Spot Sepsis)

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Anh DTV,  et al.
2025-02-05 • medRxiv
2025-02-05 • medRxiv

BACKGROUND

Circulating markers of immune and endothelial activation risk stratify infection syndromes agnostic to disease aetiology. However, their utility in c...

Journal Article
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Letter

Sustained treatment success at 12 months for drug-resistant TB patients on concomitant bedaquiline-delamanid

Chavan V, Silsarma A, Mahajan R, Khan S, Singh P,  et al.
2025-02-01 • IJTLD OPEN
2025-02-01 • IJTLD OPEN
Conference Material
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Poster

Antibiotic susceptibility patterns of bacterial pathogens isolated from hospitalized patients with advanced HIV disease (AHD) in Bihar, India

Kumar V, Murali S, Goldberg J, Alonso B, Moretó-Planas L,  et al.
2024-11-08 • MSF Scientific Days Asia 2024
2024-11-08 • MSF Scientific Days Asia 2024
Conference Material
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Poster

12-month post-treatment outcomes of previously treated drug-resistant tuberculosis patients subsequently treated with concomitant bedaquiline and delamanid +/-carbapenem, in Mumbai, India

Chavan V, Silsarma A, Khan S, Singh P, Iyer A,  et al.
2024-11-08 • MSF Scientific Days Asia 2024
2024-11-08 • MSF Scientific Days Asia 2024
Journal Article
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Research

Treatment outcomes among patients with isoniazid mono-resistant tuberculosis in Mumbai, India: A retrospective cohort study

Khan S, Silsarma A, Mahajan R, Davuluri P, Sutar N,  et al.
2024-10-12 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
2024-10-12 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases

BACKGROUND

Tub...

Conference Material
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Poster

Blinded point-of-care ultrasound to support tuberculosis diagnosis in children: a Médecins Sans Frontières cross-sectional study in Malakal, South Sudan

Niykayo LF, Mahajan R, Sagrado MJ, Ajack YBP, Chol BT,  et al.
2024-05-03 • MSF Paediatric Days 2024
2024-05-03 • MSF Paediatric Days 2024
Conference Material
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Video

Xpert Ultra in stools and urine for the diagnosis of tuberculosis in children living with HIV: Médecins Sans Frontières experience in Guinea-Bissau and South Sudan

Fidelle L, Mahajan R, Gallo J, Biague E, Goncalves R,  et al.
2024-05-03 • MSF Paediatric Days 2024
2024-05-03 • MSF Paediatric Days 2024
Conference Material
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Abstract

Xpert Ultra in stools and urine for the diagnosis of tuberculosis in children living with HIV: Médecins sans Frontières experience in Guinea-Bissau and South Sudan

Fidelle L, Mahajan R, Gallo J, Biague E, Goncalves R,  et al.
2024-05-03 • MSF Paediatric Days 2024
2024-05-03 • MSF Paediatric Days 2024
BACKGROUND AND OBJECTIVES
Over half of childhood tuberculosis (TB) remains undiagnosed yearly. TB culture is often unavailable. WHO recommends Xpert-Ultra as first test for diagnosis...
Conference Material
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Slide Presentation

Xpert Ultra in stools and urine for the diagnosis of tuberculosis in children living with HIV: Médecins Sans Frontières experience in Guinea-Bissau and South Sudan

Fidelle L, Mahajan R, Gallo J, Biague E, Goncalves R,  et al.
2024-05-03 • MSF Paediatric Days 2024
2024-05-03 • MSF Paediatric Days 2024
Journal Article
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Research

Xpert-Ultra assay on stool and urine to improve tuberculosis diagnosis in children: the Médecins Sans Frontières experience in Guinea-Bissau and South Sudan

Moretó-Planas L, Mahajan R, Fidelle Nyikayo L, Ajack YBP, Tut Chol B,  et al.
2024-05-02 • Open Forum Infectious Diseases
2024-05-02 • Open Forum Infectious Diseases
BACKGROUND
Over half of childhood tuberculosis (TB) remains undiagnosed yearly. WHO recommends Xpert-Ultra as a first paediatric diagnosis test, but microbiological confirmation rema...
Journal Article
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Research

Concomitant bedaquiline and delamanid therapy in patients with drug-resistant extra-pulmonary tuberculosis in Mumbai, India

Mongia H, Mamnoon F, Silsarma A, Mahajan R, Dalal A,  et al.
2024-04-01 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
2024-04-01 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases

BACKGROUND 

World Health Organization suggests concurrent bedaquiline-delamanid (BDQ-DLM) as part of individualised r...

Journal Article
|
Research

Antibiotic susceptibility patterns of pathogens isolated from hospitalized patients with advanced HIV disease (AHD) in Bihar, India

Kumar V, Murali S, Goldberg J, Alonso B, Moretó-Planas L,  et al.
2024-01-02 • JAC-Antimicrobial Resistance
2024-01-02 • JAC-Antimicrobial Resistance
OBJECTIVES
To describe the prevalence of common bacterial pathogens and antibiotic susceptibility patterns amongst advanced HIV disease (AHD) patients admitted between May 2019 and M...
Journal Article
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Research

Point-of-care prognostication in moderate Covid-19: Analytical validation and prognostic accuracy of a soluble urokinase plasminogen activator receptor (suPAR) rapid test

Chandna A, Mahajan R, Gautam P, Mwandigha L, Dittrich S,  et al.
2023-08-21 • PLOS Global Public Health
2023-08-21 • PLOS Global Public Health
The soluble urokinase plasminogen activator receptor (suPAR) has been proposed as a biomarker for risk stratification of patients presenting with acute infections. However, most studies ...
Journal Article
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Letter

Linezolid resistance in patients with drug-resistant TB

Vengurlekar D, Walker C, Mahajan R, Dalal A, Chavan VV,  et al.
2023-07-01 • International Journal of Tuberculosis and Lung Disease
2023-07-01 • International Journal of Tuberculosis and Lung Disease
Conference Material
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Poster

Innovative laboratory tools to improve tuberculosis diagnosis in children

Moreto-Planas L, Mahajan R, Sagrado MJ, Flevaud L, Gallo J,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Journal Article
|
Research

Point-of-care ultrasound for tuberculosis diagnosis in children: a Médecins Sans Frontières cross-sectional study in Guinea-Bissau

Moretó-Planas L, Sagrado MJ, Mahajan R, Gallo J, Biague E,  et al.
2023-05-19 • BMJ Open
2023-05-19 • BMJ Open
OBJECTIVE
Description of tuberculosis (TB)-focused point-of-care ultrasound (POCUS) findings for children with presumptive TB.

DESIGN
Cross-sectional study (July 2019 to...