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Copyright © Médecins Sans Frontières
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Showing 1 - 20 of 22 Items
Showing 1 - 20 of 22 Items
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Journal Article
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Research

Hepatitis C treatment program in Maputo, Mozambique, the challenge of genotypes and key populations: A 5-year retrospective analysis of routine programmatic data

Loarec A, Gutierrez AG, Muvale G, Couto AM, Nguyen AP,  et al.
2023-03-30 • Health Science Reports
2023-03-30 • Health Science Reports
BACKGROUND AND AIMS
Hepatitis C (HCV) programs face challenges, especially linked to key populations to achieve World Health Organization (WHO) goals of eliminating hepatitis. Médeci...
Journal Article
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Research

Epidemiological characteristics and real-world treatment outcomes of hepatitis C among HIV/HCV co-infected patients in Myanmar: A prospective cohort study

Swe TM, Johnson DC, Mar HT, Thit P, Homan T,  et al.
2023-02-17 • Health Science Reports
2023-02-17 • Health Science Reports
BACKGROUND AND AIMS
In Myanmar, public sector treatment programs for hepatitis C virus (HCV) infection were nonexistent until June 2017. WHO highlights the importance of simplificati...
Conference Material
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Abstract

A digital portable tablet audiometry monitoring tool for patients with drug-resistant tuberculosis

Arago M, Mangue M, Cumbi N, Zamudio AG, Loarec A,  et al.
2021-05-20 • MSF Scientific Days International 2021: Innovation
2021-05-20 • MSF Scientific Days International 2021: Innovation
WHAT CHALLENGE OR OPPORTUNITY DID YOU TRY TO ADDRESS? WERE EXISTING SOLUTIONS NOT AVAILABLE OR NOT GOOD ENOUGH?
Ototoxicity is an unfortunate side-effect of second-line injectable dr...
Journal Article
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Research

Cost-effectiveness of screening and treatment using direct-acting antivirals for chronic Hepatitis C virus in a primary care setting in Karachi, Pakistan

Mafirakureva N, Lim AG, Khalid GG, Aslam K, Campbell L,  et al.
2020-11-04 • Journal of Viral Hepatitis
2020-11-04 • Journal of Viral Hepatitis
Despite the availability of effective direct-acting antiviral (DAA) treatments for Hepatitis C virus (HCV) infection, many people remain undiagnosed and untreated. We assessed the cost-e...
Journal Article
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Research

Extremely Low Hepatitis C prevalence among HIV co-infected individuals in 4 countries in sub-Saharan Africa

Loarec A, Carnimeo V, Molfino L, Kizito W, Muyindike WR,  et al.
2018-11-16 • AIDS
2018-11-16 • AIDS
: A multicentric, retrospective case-series analysis (facility-based) in five sites across Kenya, Malawi, Mozambique, and Uganda screened HIV-positive adults for hepatitis C virus (HCV) ...
Journal Article
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Research

Deriving the optimal limit of detection for an HCV point-of-care test for viraemic infection: Analysis of a global dataset

Freiman JM, Wang J, Easterbrook PJ, Horsburgh CR, Marinucci F,  et al.
2019-02-21 • Journal of Hepatology
2019-02-21 • Journal of Hepatology
BACKGROUND & AIMS
Affordable point-of-care tests for hepatitis C (HCV) viraemia are needed to improve access to treatment in low- and middle-income countries. Our aims were to determ...
Journal Article
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Research

Cost and cost-effectiveness of a simplified treatment model with direct-acting antivirals for chronic hepatitis C in Cambodia

Walker JG, Mafirakureva N, Iwamoto M, Campbell L, Kim CS,  et al.
2020-05-31 • Liver International
2020-05-31 • Liver International
BACKGROUND & AIMS
In 2016, Médecins Sans Frontières established the first general population Hepatitis C virus (HCV) screening and treatment site in Cambodia, offering free direct-ac...
Conference Material
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Poster

Integrated hepatitis B prevention in PMTCT program in Chamanculo maternity, Maputo, Mozambique

Antabak NT, Loarec A, Nguyen AP, Eliseo NDM, Molfino L,  et al.
2018-05-04 • MSF Scientific Days International 2018: Research
2018-05-04 • MSF Scientific Days International 2018: Research
Journal Article
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Research

Prevalence of HIV, viral hepatitis B/C and tuberculosis and treatment outcomes among people who use drugs: Results from the implementation of the first drop-in-center in Mozambique

Sema Baltazar C, Kellogg TA, Boothe M, Loarec A, de Abreu E,  et al.
2021-04-01 • International Journal of Drug Policy
2021-04-01 • International Journal of Drug Policy
BACKGROUND
People who use drugs (PWUD) which includes both people who inject drugs (PWID) and non-injection drug users (NIDU) are marginalized, experience high levels of stigma and d...
Journal Article
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Research

Hepatitis C viraemic and seroprevalence and risk factors for positivity in Northwest Cambodia: a household cross-sectional serosurvey

Lynch E, Falq G, Sun C, Bunchhoeung PDT, Huerga H,  et al.
2021-02-26 • BMC Infectious Diseases
2021-02-26 • BMC Infectious Diseases
BACKGROUND
Despite a dramatic reduction in HCV drug costs and simplified models of care, many countries lack important information on prevalence and risk factors to structure effecti...
Journal Article
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Research

High burden of cryptococcal antigenemia and meningitis among patients presenting at an emergency department in Maputo, Mozambique

Deiss R, Loreti C, Gutierrez AG, Filipe E, Tatia M,  et al.
2021-04-26 • PLOS One
2021-04-26 • PLOS One
BACKGROUND
Cryptococcal meningitis is a leading cause of HIV-related mortality in sub-Saharan Africa, however, screening for cryptococcal antigenemia has not been universally impleme...
Journal Article
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Research

Determining the lower limit of detection required for HCV viral load assay for test of cure following direct-acting antiviral based treatment regimens: evidence from a global dataset

Morgan JR, Marsh E, Savinkina A, Shilton S, Shadaker S,  et al.
2022-03-12 • Journal of Viral Hepatitis
2022-03-12 • Journal of Viral Hepatitis
Achieving global elimination of hepatitis C virus requires a substantial scale-up of testing. Point-of-care HCV viral load assays are available as an alternative to laboratory-based assa...
Conference Material
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Slide Presentation

A digital portable tablet audiometry monitoring tool for patients with drug-resistant tuberculosis

Arago M, Mangue M, Cumbi N, Zamudio AG, Loarec A,  et al.
2021-05-20 • MSF Scientific Days International 2021: Innovation
2021-05-20 • MSF Scientific Days International 2021: Innovation
Journal Article
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Research

An intensive model of care for hepatitis C virus screening and treatment with direct-acting antivirals in people who inject drugs in Nairobi, Kenya: a model-based cost-effectiveness analysis

Mafirakureva N, Stone J, Fraser H, Nzomukunda Y, Maina A,  et al.
2020-06-29 • Society
2020-06-29 • Society
BACKGROUND AND AIMS
Hepatitis C virus (HCV) treatment is essential for eliminating HCV in people who inject drugs (PWID), but has limited coverage in resource-limited settings. We me...
Protocol
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Research Protocol

Field evaluation of the performance of HCV Serological Rapid Diagnostic Tests among HCV/HIV co-infected patients

Gupta E, Carnimeo V, Samukcham I, Loarec A, Mahajan S,  et al.
2018-07-01
2018-07-01
P R O T O C O L S U M M A R Y
 Title: Field evaluation of the performance of HCV Serological Rapid Diagnostic Tests among
HCV/HIV co-infected patients.
 Aim: To evaluate...
Journal Article
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Research

Deriving the optimal limit of detection for an HCV

Freiman JM, Wang J, Easterbrook PJ, Horsburgh CR, Marinucci F,  et al.
2019-07-01 • Journal of Hepatology
2019-07-01 • Journal of Hepatology
Journal Article
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Research

Demonstration of the diagnostic agreement of capillary and venous blood samples, using hepatitis-C virus SD Bioline © rapid test: A clinic-based study

Sun C, Iwamoto M, Calzia A, Sreng B, Yann S,  et al.
2019-02-01 • Journal of Clinical Virology
2019-02-01 • Journal of Clinical Virology
BACKGROUND
Simplifying hepatitis C virus (HCV) screening is a key step in achieving the elimination of HCV as a global public health threat by 2030.

OBJECTIVES
The objec...
Journal Article
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Research

Effects and cost of different strategies to eliminate hepatitis C virus transmission in Pakistan: a modelling analysis

Lim AG, Walker JG, Mafirakureva N, Khalid GG, Qureshi H,  et al.
2020-03-01 • Lancet Global Health
2020-03-01 • Lancet Global Health
BACKGROUND
The WHO elimination strategy for hepatitis C virus advocates scaling up screening and treatment to reduce global hepatitis C incidence by 80% by 2030, but little is known ...
Journal Article
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Research

Cost and cost-effectiveness of a real-world HCV treatment program among HIV-infected individuals in Myanmar

Marquez LK, Chaillon A, Soe KT, Johnson DC, Zosso JM,  et al.
2021-02-01 • BMJ Global Health
2021-02-01 • BMJ Global Health
INTRODUCTION
Over half of those hepatitis C virus (HCV)/HIV coinfected live in low-income and middle-income countries, and many remain undiagnosed or untreated. In 2016, Médecins San...
Journal Article
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Research

Prevention of mother-to-child transmission of hepatitis B virus in antenatal care and maternity services, Mozambique

Loarec A, Nguyen AP, Chissano M, Madeira N, Rusch B,  et al.
2021-12-02 • Bulletin of the World Health Organization
2021-12-02 • Bulletin of the World Health Organization
OBJECTIVE
To pilot an intervention on the prevention of mother-to-child transmission (PMTCT) of hepatitis B virus (HBV) in an antenatal care and maternity unit in Maputo, Mozambique,...