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Showing 1 - 20 of 44 Items
Showing 1 - 20 of 44 Items
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Journal Article
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Research

Trypanosoma brucei gambiense trypanosomiasis in Terego county, Northern Uganda, 1996: a lot quality assurance sampling survey

Hutin Y, Legros D, Owini V, Brown V, Lee EC,  et al.
2004-04-01 • American Journal of Tropical Medicine and Hygiene
2004-04-01 • American Journal of Tropical Medicine and Hygiene
We estimated the pre-intervention prevalence of Trypanosoma brucei gambiense (Tbg) trypanosomiasis using the lot quality assurance sampling (LQAS) methods in 14 parishes of Terego County...
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Research
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Research

Therapeutic Failure of Melarsoprol Among Patients Treated for Late Stage T.b. Gambiense Human African Trypanosomiasis in Uganda

Journal Article
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Commentary
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Review
Journal Article
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Research
Journal Article
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Commentary

Safe water, sanitation, hygiene, and a cholera vaccine

Azman AS, Ivers LI, Legros D, Luquero FJ, Mintz ED
2016-01-02 • Lancet
2016-01-02 • Lancet
Journal Article
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Letter

Rapid assessment of mortality and malnutrition in Afghanistan

Piola P, Tachon JL, Brown V, Ligozat L, Veyrier E,  et al.
2002-09-11 • JAMA
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Research
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Review
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Review

Anthropometric indices used for the diagnosis of malnutrition in adolescents and adults: review of the literature

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Research
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Research

Feasibility of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban cholera-endemic setting in Mozambique

Cavailler P, Perroud V, Mcchesney M, Ampuero S, Guerin PJ,  et al.
2006-05-29 • Vaccine
2006-05-29 • Vaccine
We conducted a study to assess the feasibility and the potential vaccine coverage of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban endemic neighbourhood o...

Immune responses to an oral cholera vaccine in internally displaced persons in South Sudan

Iyer AS, Ryan ET, Martin S, Legros D, Lessler J,  et al.
2016-10-24 • Scientific Reports
2016-10-24 • Scientific Reports
Despite recent large-scale cholera outbreaks, little is known about the immunogenicity of oral cholera vaccines (OCV) in African populations, particularly among those at highest cholera ...

The Efficacy of Chloroquine for the Treatment of Acute, Uncomplicated, Plasmodium Falciparum Malaria in Laos

Guthmann JP, Kasparian S, Phetsouvanh R, Nathan N, Garcia MG,  et al.
2002-09-01 • Annals of Tropical Medicine and Parasitology
2002-09-01 • Annals of Tropical Medicine and Parasitology
To assess the local efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria, children and adults from Sekong province (an area of Laos with a low...

Ceftriaxone as effective as long-acting chloramphenicol in short-course treatment of meningococcal meningitis during epidemics: a randomised non-inferiority study

Nathan N, Borel T, Djibo A, Evans D, Djibo S,  et al.
2008-04-14 • Lancet
2008-04-14 • Lancet
BACKGROUND: In sub-Saharan Africa in the 1990s, more than 600,000 people had epidemic meningococcal meningitis, of whom 10% died. The current recommended treatment by WHO is short-course...
Legros D, Fournier C, Gastellu-Etchegorry M, Maiso F, Szumilin E
1999-07-01 • Bulletin de la Société de Pathologie Exotique
1999-07-01 • Bulletin de la Société de Pathologie Exotique
The failure rate of melarsoprol after treatment of late stage cases of Human African Trypanosomiasis (HAT) is usually under 7%, even though the drug has been used for such treatment over...

Consequences of armed conflict for an ethnic Karen population

Checchi F, Elder G, Schäfer M, Drouhin E, Legros D
2003-07-05 • Lancet
2003-07-05 • Lancet

Prevention and control of cholera with household and community water, sanitation and hygiene (WASH) interventions: A scoping review of current international guidelines

D Mello Guyett L, Gallandat K, Van der Bergh R, Taylor DL, Bulit G,  et al.
2020-01-08 • PLOS One
2020-01-08 • PLOS One
INTRODUCTION:
Cholera remains a frequent cause of outbreaks globally, particularly in areas with inadequate water, sanitation and hygiene (WASH) services. Cholera is spread through ...

Assessing antimalarial efficacy in a time of change to artemisinin-based combination therapies: The role of Médecins Sans Frontières

Guthmann JP, Checchi F, van den Broek IVF, Balkan S, Van Herp M,  et al.
2008-08-05 • PLOS Medicine
2008-08-05 • PLOS Medicine
2002-09-11 • JAMA
To the Editor: In November 2001 the possibility of widespread malnutrition was reported in Ghor province, Afghanistan, particularly in the Chaghcharan district, which had received no ext...

Treatment of human African trypanosomiasis--present situation and needs for research and development

Legros D, Ollivier G, Gastellu-Etchegorry M, Paquet C, Burri C,  et al.
2002-07-01 • Lancet Infectious Diseases
2002-07-01 • Lancet Infectious Diseases
Human African trypanosomiasis re-emerged in the 1980s. However, little progress has been made in the treatment of this disease over the past decades. The first-line treatment for second-...

Post-licensure deployment of oral cholera vaccines: a systematic review

Martin S, Lopez AMZ, Bellos A, Deen JL, Ali MI,  et al.
2014-09-29 • Bulletin of the World Health Organization
2014-09-29 • Bulletin of the World Health Organization
OBJECTIVE
To describe and analyse the characteristics of oral cholera vaccination campaigns; including location, target population, logistics, vaccine coverage and delivery costs.

Mapping the burden of cholera in sub-Saharan Africa and implications for control: an analysis of data across geographical scales

Lessler J, Moore SM, Luquero FJ, McKay H, Grais RF,  et al.
2018-05-01 • Lancet
2018-05-01 • Lancet
Cholera remains a persistent health problem in sub-Saharan Africa and worldwide. Cholera can be controlled through appropriate water and sanitation, or by oral cholera vaccination, which...
Dorlencourt F, Priem V, Legros D
2000-01-01 • Bulletin de la Société de Pathologie Exotique
2000-01-01 • Bulletin de la Société de Pathologie Exotique
The International Dietary Energy Consultative Group, sponsored by the World Health Organization (WHO), has done most of the research conducted in the field of adult malnutrition in the l...

Treatment of severe malnutrition with 2-day intramuscular ceftriaxone vs 5-day amoxicillin

Dubray C, Ibrahim SA, Abdelmutalib M, Guerin PJ, Dantoine F,  et al.
2008-03-01 • Annals of Tropical Paediatrics
2008-03-01 • Annals of Tropical Paediatrics
BACKGROUND: Systemic antibiotics are routinely prescribed for severe acute malnutrition (SAM). However, there is no consensus regarding the most suitable regimen. In a therapeutic feedin...

First outbreak response using an oral cholera vaccine in Africa: vaccine coverage, acceptability and surveillance of adverse events, Guinea, 2012

Luquero FJ, Grout L, Ciglenecki I, Sakoba K, Traore B,  et al.
2013-10-17 • PLOS Neglected Tropical Diseases
2013-10-17 • PLOS Neglected Tropical Diseases
BACKGROUND
Despite World Health Organization (WHO) prequalification of two safe and effective oral cholera vaccines (OCV), concerns about the acceptability, potential diversion of re...

Meningitis serogroup W135 outbreak, Burkina Faso, 2002

Nathan N, Rose AMC, Legros D, Tiendrebeogo SRM, Bachy C,  et al.
2007-06-01 • Emerging Infectious Diseases
2007-06-01 • Emerging Infectious Diseases
In 2002, the largest epidemic of Neisseria meningitidis serogroup W135 occurred in Burkina Faso. The highest attack rate was in children <5 years of age. We describe cases from 1 distric...

A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995)

Kerneis S, Guerin PJ, von Seidlein L, Legros D, Grais RF
2009-02-13 • PLOS One
2009-02-13 • PLOS One
BACKGROUND: Shigella dysenteriae type 1 (Sd1) is a cause of major dysentery outbreaks, particularly among children and displaced populations in tropical countries. Although outbreaks con...

El Niño and the shifting geography of cholera in Africa

Moore SM, Azman AS, Zaitchik BF, Mintz ED, Brunkard J,  et al.
2017-04-10 • Proceedings of the National Academy of Sciences
2017-04-10 • Proceedings of the National Academy of Sciences
The El Niño Southern Oscillation (ENSO) and other climate patterns can have profound impacts on the occurrence of infectious diseases ranging from dengue to cholera. In Africa, El Niño c...