Search Results | MSF Science Portal

Journal Article

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Research

Iyer AS, Ryan ET, Martin S, Legros D, Lessler J, et al.

2016-10-24 • Scientific Reports

Despite recent large-scale cholera outbreaks, little is known about the immunogenicity of oral cholera vaccines (OCV) in African populations, particularly among those at highest cholera ...

Journal Article

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Research

Cavailler P, Perroud V, Mcchesney M, Ampuero S, Guerin PJ, et al.

2006-05-29 • Vaccine

We conducted a study to assess the feasibility and the potential vaccine coverage of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban endemic neighbourhood o...

Journal Article

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Research

Hutin Y, Legros D, Owini V, Brown V, Lee EC, et al.

2004-04-01 • American Journal of Tropical Medicine and Hygiene

We estimated the pre-intervention prevalence of Trypanosoma brucei gambiense (Tbg) trypanosomiasis using the lot quality assurance sampling (LQAS) methods in 14 parishes of Terego County...

Journal Article

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Research

Guthmann JP, Kasparian S, Phetsouvanh R, Nathan N, Garcia MG, et al.

2002-09-01 • Annals of Tropical Medicine and Parasitology

To assess the local efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria, children and adults from Sekong province (an area of Laos with a low...

Journal Article

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Research

Nathan N, Borel T, Djibo A, Evans D, Djibo S, et al.

2008-04-14 • Lancet

BACKGROUND: In sub-Saharan Africa in the 1990s, more than 600,000 people had epidemic meningococcal meningitis, of whom 10% died. The current recommended treatment by WHO is short-course...

Journal Article

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Research

Legros D, Fournier C, Gastellu-Etchegorry M, Maiso F, Szumilin E

1999-07-01 • Bulletin de la Société de Pathologie Exotique

The failure rate of melarsoprol after treatment of late stage cases of Human African Trypanosomiasis (HAT) is usually under 7%, even though the drug has been used for such treatment over...

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Commentary

Checchi F, Elder G, Schäfer M, Drouhin E, Legros D

2003-07-05 • Lancet

Journal Article

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Commentary

Azman AS, Ivers LI, Legros D, Luquero FJ, Mintz ED

2016-01-02 • Lancet

Journal Article

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Research

Guthmann JP, Checchi F, van den Broek IVF, Balkan S, Van Herp M, et al.

2008-08-05 • PLOS Medicine

Journal Article

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Review

D Mello Guyett L, Gallandat K, Van der Bergh R, Taylor DL, Bulit G, et al.

2020-01-08 • PLOS One

INTRODUCTION:
Cholera remains a frequent cause of outbreaks globally, particularly in areas with inadequate water, sanitation and hygiene (WASH) services. Cholera is spread through ...

Journal Article

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Letter

Piola P, Tachon JL, Brown V, Ligozat L, Veyrier E, et al.

2002-09-11 • JAMA

To the Editor: In November 2001 the possibility of widespread malnutrition was reported in Ghor province, Afghanistan, particularly in the Chaghcharan district, which had received no ext...

Journal Article

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Research

Lessler J, Moore SM, Luquero FJ, McKay H, Grais RF, et al.

2018-05-01 • Lancet

Cholera remains a persistent health problem in sub-Saharan Africa and worldwide. Cholera can be controlled through appropriate water and sanitation, or by oral cholera vaccination, which...

Journal Article

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Research

Legros D, Ollivier G, Gastellu-Etchegorry M, Paquet C, Burri C, et al.

2002-07-01 • Lancet Infectious Diseases

Human African trypanosomiasis re-emerged in the 1980s. However, little progress has been made in the treatment of this disease over the past decades. The first-line treatment for second-...

Journal Article

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Review

Martin S, Lopez AMZ, Bellos A, Deen JL, Ali MI, et al.

2014-09-29 • Bulletin of the World Health Organization

OBJECTIVE
To describe and analyse the characteristics of oral cholera vaccination campaigns; including location, target population, logistics, vaccine coverage and delivery costs.

Journal Article

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Research

Luquero FJ, Grout L, Ciglenecki I, Sakoba K, Traore B, et al.

2013-10-17 • PLOS Neglected Tropical Diseases

BACKGROUND
Despite World Health Organization (WHO) prequalification of two safe and effective oral cholera vaccines (OCV), concerns about the acceptability, potential diversion of re...

Journal Article

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Review

Dorlencourt F, Priem V, Legros D

2000-01-01 • Bulletin de la Société de Pathologie Exotique

The International Dietary Energy Consultative Group, sponsored by the World Health Organization (WHO), has done most of the research conducted in the field of adult malnutrition in the l...

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Research

Dubray C, Ibrahim SA, Abdelmutalib M, Guerin PJ, Dantoine F, et al.

2008-03-01 • Annals of Tropical Paediatrics

BACKGROUND: Systemic antibiotics are routinely prescribed for severe acute malnutrition (SAM). However, there is no consensus regarding the most suitable regimen. In a therapeutic feedin...

Journal Article

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Research

Nathan N, Rose AMC, Legros D, Tiendrebeogo SRM, Bachy C, et al.

2007-06-01 • Emerging Infectious Diseases

In 2002, the largest epidemic of Neisseria meningitidis serogroup W135 occurred in Burkina Faso. The highest attack rate was in children <5 years of age. We describe cases from 1 distric...

Journal Article

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Research

Kerneis S, Guerin PJ, von Seidlein L, Legros D, Grais RF

2009-02-13 • PLOS One

BACKGROUND: Shigella dysenteriae type 1 (Sd1) is a cause of major dysentery outbreaks, particularly among children and displaced populations in tropical countries. Although outbreaks con...

Journal Article

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Research

Guthmann JP, Pinoges LLP, Checchi F, Cousens S, Balkan S, et al.

2006-11-01 • Antimicrobial Agents and Chemotherapy

The objectives of these analyses were to assess the feasibility of the latest WHO recommendations (28-day follow-up with PCR genotyping) for the assessment of antimalarial drug efficacy ...

Science Portal

Immune responses to an oral cholera vaccine in internally displaced persons in South Sudan

Feasibility of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban cholera-endemic setting in Mozambique

Trypanosoma brucei gambiense trypanosomiasis in Terego county, Northern Uganda, 1996: a lot quality assurance sampling survey

The Efficacy of Chloroquine for the Treatment of Acute, Uncomplicated, Plasmodium Falciparum Malaria in Laos

Ceftriaxone as effective as long-acting chloramphenicol in short-course treatment of meningococcal meningitis during epidemics: a randomised non-inferiority study

Therapeutic Failure of Melarsoprol Among Patients Treated for Late Stage T.b. Gambiense Human African Trypanosomiasis in Uganda

Consequences of armed conflict for an ethnic Karen population

Safe water, sanitation, hygiene, and a cholera vaccine

Assessing antimalarial efficacy in a time of change to artemisinin-based combination therapies: The role of Médecins Sans Frontières

Prevention and control of cholera with household and community water, sanitation and hygiene (WASH) interventions: A scoping review of current international guidelines

Rapid assessment of mortality and malnutrition in Afghanistan

Mapping the burden of cholera in sub-Saharan Africa and implications for control: an analysis of data across geographical scales

Treatment of human African trypanosomiasis--present situation and needs for research and development

Post-licensure deployment of oral cholera vaccines: a systematic review

First outbreak response using an oral cholera vaccine in Africa: vaccine coverage, acceptability and surveillance of adverse events, Guinea, 2012

Anthropometric indices used for the diagnosis of malnutrition in adolescents and adults: review of the literature

Treatment of severe malnutrition with 2-day intramuscular ceftriaxone vs 5-day amoxicillin

Meningitis serogroup W135 outbreak, Burkina Faso, 2002

A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995)

Methodological issues in the assessment of antimalarial drug treatment: Analysis of 13 studies in eight African countries from 2001 to 2004