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Journal Article
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Research

Body mass index trajectories and association with tuberculosis risk in a cohort of household contacts in Southern Africa

Larsson L, Calderwood CJ, Marambire ET, Held K, Banze D,  et al.
2025-04-28 • Clinical Infectious Diseases
2025-04-28 • Clinical Infectious Diseases

BACKGROUND

Studies have demonstrated an inverse log-linear relationship between body mass index (BMI) and tuberculosis incidence. However, a person’s BMI is dyn...

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Editorial
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Commentary
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Research
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Review

Risk factors, barriers and facilitators for linkage to antiretroviral therapy care: a systematic review

Govindasamy D, Ford NP, Kranzer K
2012-10-23 • AIDS
2012-10-23 • AIDS
Journal Article
|
Research

Urgent request for pretomanid label expansion to align with WHO guidelines and improve treatment accessibility and efficacy

Kuksa L, Andrejak C, Haecker B, Bothamley G, Calcagno A,  et al.
2025-03-01 • IJTLD OPEN
2025-03-01 • IJTLD OPEN

Pretomanid is a key anti-TB drug included in the WHO list of essential medications. The current EMA-approve...

Caring for adolescents and young adults with tuberculosis or at risk of tuberculosis: Consensus statement from an international expert panel

Chiang SS, Waterous PM, Atieno VF, Bernays S, Bondarenko Y,  et al.
2023-03-01 • Journal of Adolescent Health
2023-03-01 • Journal of Adolescent Health

MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era

Beckert P, Sanchez-Padilla E, Merker M, Dreyer V, Kohl TA,  et al.
2020-11-25 • Genome Medicine
2020-11-25 • Genome Medicine
Background
Multidrug-resistant (MDR) Mycobacterium tuberculosis complex strains not detected by commercial molecular drug susceptibility testing (mDST) assays due to the RpoB I491F ...

Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years

Bygrave H, Ford NP, van Cutsem G, Hilderbrand K, Jouquet G,  et al.
2011-03-01 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
2011-03-01 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
BACKGROUND
The latest World Health Organization guidelines recommend replacing stavudine with tenofovir or zidovudine in first-line antiretroviral therapy in resource-limited setting...

Trends in loss to follow-up among migrant workers on antiretroviral therapy in a community cohort in Lesotho

Bygrave H, Kranzer K, Hilderbrand K, Whittall J, Jouquet G,  et al.
2010-10-08 • PLOS One
2010-10-08 • PLOS One
BACKGROUND
The provision of antiretroviral therapy (ART) to migrant populations raises particular challenges with respect to ensuring adequate treatment support, adherence, and reten...

Superior virologic and treatment outcomes when viral load is measured at 3 months compared to 6 months on antiretroviral therapy

Kerschberger B, Boulle AM, Kranzer K, Hilderbrand K, Schomaker M,  et al.
2015-09-23 • Journal of the International AIDS Society
2015-09-23 • Journal of the International AIDS Society
Introduction
Routine viral load (VL) monitoring is utilized to assess antiretroviral therapy (ART) adherence and virologic failure, and it is currently scaled-up in many resource-con...

Safety of efavirenz in first-trimester of pregnancy: a systematic review and meta-analysis of outcomes from observational cohorts

Ford NP, Mofenson L, Kranzer K, Medu L, Frigati L,  et al.
2010-06-19 • AIDS
2010-06-19 • AIDS
INTRODUCTION
Primate studies and some observational human data have raised concern regarding an association of first-trimester efavirenz exposure with central nervous system congenit...

Antiretroviral Therapy outcomes among adolescents and youth in rural Zimbabwe

Bygrave H, Mtangirwa J, Ncube K, Ford NP, Kranzer K,  et al.
2012-12-20 • PLOS One
2012-12-20 • PLOS One
Around 2 million adolescents and 3 million youth are estimated to be living with HIV worldwide. Antiretroviral outcomes for this group appear to be worse compared to adults. We report an...