Sprecher A, Cross RW, Marzi A, Martins KA, Wolfe D, et al.
2023-08-19 • Journal of Infectious Diseases
2023-08-19 • Journal of Infectious Diseases
Although there are now approved treatments and vaccines for Ebola virus disease (EVD), the case fatality of EVD remains unacceptably high even when treated with the newly approved therap...
Rosenke K, Adjemian J, Munster VJ, Marzi A, Falzarano D, et al.
2016-08-15 • Clinical Infectious Diseases
2016-08-15 • Clinical Infectious Diseases
BACKGROUND The ongoing Ebola outbreak in West Africa has resulted in 28 646 suspected, probable, and confirmed Ebola virus infections. Nevertheless, malaria remains a large public he...
Poliquin PG, Vogt F, Kasztura M, Leung A, Deschambault Y, et al.
2016-06-30 • Journal of Infectious Diseases
2016-06-30 • Journal of Infectious Diseases
BACKGROUND Ebola viruses (EBOVs) are primarily transmitted by contact with infected body fluids. Ebola treatment centers (ETCs) contain areas that are exposed to body fluids through ...
Nanclares C, Kapetshi J, Lionetto F, de la Rosa O, Muyembe Tamfun JJ, et al.
2016-09-01 • Emerging Infectious Diseases
2016-09-01 • Emerging Infectious Diseases
During July-November 2014, the Democratic Republic of the Congo underwent its seventh Ebola virus disease (EVD) outbreak. The etiologic agent was Zaire Ebola virus; 66 cases were reporte...
de la Vega MA, Bello A, Chaillet P, Kobinger GP
2016-05-13 • Expert Review of Anti-Infective Therapy
2016-05-13 • Expert Review of Anti-Infective Therapy
The magnitude of the 2014–2016 West African Ebola virus outbreak has highlighted the importance of immediate and rapid deployment of control measures in affected areas. While many prophy...
Cnops L, van Griensven J, Honko AN, Bausch DG, Sprecher A, et al.
2016-06-10 • Lancet Infectious Diseases
2016-06-10 • Lancet Infectious Diseases
Quantitative measurement of viral load is an important parameter in the management of filovirus disease outbreaks because viral load correlates with severity of disease, survival, and in...
Wong G, Qiu X, Bi Y, Formenty P, Sprecher A, et al.
2016-10-15 • Journal of Infectious Diseases
2016-10-15 • Journal of Infectious Diseases
Cases of relapsed Ebola virus disease involving symptoms in the central nervous system are reminiscent of our past observations with some nonhuman primates (NHPs) that survived acute Ebo...
Sprecher A, Feldman H, Hensley L, Kobinger GP, Nichol ST, et al.
2016-02-24 • Nature Microbiology
2016-02-24 • Nature Microbiology
Concern over Ebola becoming endemic in West Africa has appeared in the medical and lay media. Routes of transmission, rates of viral evolution, suitability of humans as hosts and rarity ...
Nsio JM, Kapteshi K, Makiala S, Raymond F, Tshapenda G, et al.
2019-04-03 • Journal of Infectious Diseases
2019-04-03 • Journal of Infectious Diseases
BACKGROUND In 2017, the Democratic Republic of the Congo (DRC) recorded its eighth Ebola virus disease (EVD) outbreak, approximately 3 years after the previous outbreak.
de Wit E, Falzarano D, Onyango C, Rosenke K, Marzi A, et al.
2016-02-01 • Emerging Infectious Diseases
2016-02-01 • Emerging Infectious Diseases
Malaria is a major public health concern in the countries affected by the Ebola virus disease epidemic in West Africa. We determined the feasibility of using molecular malaria diagnostic...
Lokuge K, Caleo GNC, Greig J, Duncombe J, McWilliam N, et al.
2016-03-09 • PLOS Neglected Tropical Diseases
2016-03-09 • PLOS Neglected Tropical Diseases
The scale and geographical distribution of the current outbreak in West Africa raised doubts as to the effectiveness of established methods of control. Ebola Virus Disease (EVD) was firs...
Sprecher A, Caluwaerts C, Draper M, Feldmann H, Frey C, et al.
2015-03-27 • Journal of Infectious Diseases
2015-03-27 • Journal of Infectious Diseases
Personal protective equipment (PPE) is an important part of worker protection during filovirus outbreaks. The need to protect against a highly virulent fluid-borne pathogen in the tropic...
Caleo GNC, Theocharaki F, Lokuge K, Weiss HA, Inamdar L, et al.
2020-06-25 • Lancet Infectious Diseases
2020-06-25 • Lancet Infectious Diseases
Background
Ebola virus disease case definition is a crucial surveillance tool to detect suspected cases for referral and as a screening tool for clinicians to support admission and ...
Osterholm M, Moore K, Kelley N, Brosseau L, Wong G, et al.
2015-02-19 • mBio
2015-02-19 • mBio
Available evidence demonstrates that direct patient contact and contact with infectious body fluids are the primary modes for Ebola virus transmission, but this is based on a limited num...