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Copyright © Médecins Sans Frontières
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Showing 1 - 8 of 8 Items
Showing 1 - 8 of 8 Items
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Journal Article
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Research

Using an analogue-digital hybrid clinical data management platform during a two-dose preventive Ebola virus vaccine trial in Goma, the Democratic Republic of the Congo

Brindle HE, Tetsa-Tata D, Edwards T, Choi EML, Kasonia K,  et al.
2025-05-02 • PLOS Global Public Health
2025-05-02 • PLOS Global Public Health

Clinical trials in settings with intermittent or non-existent internet and power connectivity, for example ...

Journal Article
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Research

Pregnancy and neonatal outcomes in Eastern Democratic Republic of the Congo: a systematic review

Kasonia K, Brindle H, Manno D, Edwards T, Gardais S,  et al.
2024-12-05 • Frontiers in Global Women's Health
2024-12-05 • Frontiers in Global Women's Health

BACKGROUND

Conflict is known to impact maternal and neonatal health in Eastern Democratic Republic of the Congo (DRC), an area of longstanding insecurity. We co...

Journal Article
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Research

Immunogenicity of an extended dose interval for the Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen in adults and children in the Democratic Republic of the Congo

Choi EM, Kasonia K, Kavunga-Membo H, Mukadi-Bamuleka D, Soumah A,  et al.
2024-07-26 • Vaccines
2024-07-26 • Vaccines

During the 2018–2020 Ebola virus disease outbreak in Democratic Republic of the Congo, a phase 3 trial of the Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine (DRC-EB-001) commenced in Goma, wit...

Journal Article
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Research

Delivery and safety of a two-dose preventive Ebola virus disease vaccine in pregnant and non-pregnant participants during an outbreak in the Democratic Republic of the Congo

Kavunga-Membo H, Watson-Jones D, Kasonia K, Edwards T, Camacho A,  et al.
2024-07-23 • Vaccines
2024-07-23 • Vaccines

During the 2018–2020 Ebola virus disease (EVD) outbreak, residents in Goma, Democratic Republic of the Congo, were offered a two-dose prophylactic EVD vaccine. This was the first stud...

Journal Article
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Research

Cholera deaths during outbreaks in Uvira, Eastern Democratic Republic of the Congo, 10-35 months after mass vaccination

Bugeme PM, Xu H, Hutchins C, Dent J, Saidi JM,  et al.
2024-02-01 • Open Forum Infectious Diseases
2024-02-01 • Open Forum Infectious Diseases
Our understanding of the burden and drivers of cholera mortality is hampered by limited surveillance and confirmation capacity. Leveraging enhanced clinical and laboratory surveillance i...
Journal Article
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Book Chapter

Building partnerships and confronting challenges: Implementation of an ebola virus vaccine clinical study during an outbreak in the Democratic Republic of the Congo

Bausch DG, Kavunga-Membo H, Grais RF, Imbault N, Roberts N,  et al.
2023-12-31 • Nephrology Dialysis Transplantation
2023-12-31 • Nephrology Dialysis Transplantation

Research, especially clinical trials, during outbreaks often poses enormous challenges, and up until very recent times was often considered almost impossible. However, for diseases su...

Journal Article
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Research

Protection, health seeking, or a laissez-passer: Participants’ decision-making in an EVD vaccine trial in the eastern Democratic Republic of the Congo

James M, Kasereka JG, Kasiwa B, Kavunga-Membo H, Kambale K,  et al.
2023-03-15 • Social Science and Medicine
2023-03-15 • Social Science and Medicine
During the 10th Ebola virus disease (EVD) epidemic in the eastern Democratic Republic of the Congo (DRC) (2018-2020), two experimental EVD vaccines were deployed in North Kivu. This prov...
Protocol
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Research Protocol

Protocol for a phase 3 trial to evaluate the effectiveness and safety of a heterologous, two-dose vaccine for Ebola virus disease in the Democratic Republic of the Congo

Watson-Jones D, Kavunga-Membo H, Grais RF, Ahuka S, Roberts N,  et al.
2022-03-08 • BMJ Open
2022-03-08 • BMJ Open
INTRODUCTION
Ebola virus disease (EVD) continues to be a significant public health problem in sub-Saharan Africa, especially in the Democratic Republic of the Congo (DRC). Large-scal...