Search Results | MSF Science Portal

Journal Article

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Research

Schramm B, Temfack E, Descamps D, Nicholas S, Peytavin G, et al.

2022-08-01 • Lancet HIV

BACKGROUND
Many countries are now replacing non-nucleoside reverse transcriptase inhibitor (NNRTI)-based first-line antiretroviral therapy (ART) with a regimen containing tenofovir d...

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Commentary

Ford NP, Geng EH, Ellman T, Orrell C, Ehrenkranz PD, et al.

2020-02-14 • PLOS Medicine

Journal Article

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Research

Kanyerere H, Mganga A, Harries AD, Tayler-Smith K, Jahn A, et al.

2014-06-21 • Public Health Action

From 2000 to 2012, Malawi scaled up antiretroviral therapy (ART) from <3000 to 404 905 persons living with HIV/AIDS (human immunodeficiency virus/acquired immune-deficiency syndrome), re...

Journal Article

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Review

Telisinghe L, Charalambous S, Topp SM, Herce ME, Hoffmann CJ, et al.

2016-07-14 • Lancet

Given the dual epidemics of HIV and tuberculosis in sub-Saharan Africa and evidence suggesting a disproportionate burden of these diseases among detainees in the region, we aimed to inve...

Journal Article

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Commentary

Ehrenkranz PD, Baptiste SL, Bygrave H, Ellman T, Doi N, et al.

2019-05-29 • PLOS Medicine

In a Policy Forum, Peter Ehrenkranz and colleagues discuss the contribution of CD4 and viral load testing to outcomes for people with HIV in low- and middle-income countries.

Journal Article

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Research

Makombe SD, Jahn A, Tweya H, Chuka S, Yu JKL, et al.

2007-11-01 • Bulletin of the World Health Organization

OBJECTIVE
To assess the human resources impact of Malawis rapidly growing antiretroviral therapy (ART) programme and balance this against the survival benefit of health-care workers ...

Journal Article

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Research

Keiser O, Tweya H, Boulle AM, Braitstein P, Schechter M, et al.

2009-09-10 • AIDS

BACKGROUND
In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring ...

Journal Article

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Commentary

Kanyerere H, Mganga A, Harries AD, Tayler-Smith K, Jahn A, et al.

2014-06-21 • Public Health Action

Journal Article

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Review

Zachariah R, Mwagomba B, Misinde D, Mandere BC, Bemeyani A, et al.

2011-03-02 • Transactions of the Royal Society of Tropical Medicine and Hygiene

Vital registration - the systematic recording of births and deaths - has both legal and health significance. In particular, accurate recording and reporting of vital statistics are publi...

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Commentary

Schouten EJ, Jahn A, Midiani D, Makombe SD, Mnthambala A, et al.

2011-07-16 • Lancet

Journal Article

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Research

Kanyerere H, Girma B, Mpunga J, Tayler-Smith K, Harries AD, et al.

2016-12-21 • Public Health Action

SETTING
For 30 years, Malawi has experienced a dual epidemic of human immunodeficiency virus (HIV) infection and tuberculosis (TB) that has recently begun to be attenuated by the sca...

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Research

Kanyerere H, Mganga A, Harries AD, Tayler-Smith K, Zachariah R, et al.

2015-06-21 • Public Health Action

Between 2000 and 2012, the annual numbers of patients treated for tuberculosis (TB) in Malawi declined by 28%, from 28 234 to 20 463. During this time, the proportion of TB patients test...

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Research

Makombe SD, Hochgesang M, Jahn A, Tweya H, Hedt BL, et al.

2008-04-01 • Bulletin of the World Health Organization

PROBLEM
As national antiretroviral treatment (ART) programmes scale-up, it is essential that information is complete, timely and accurate for site monitoring and national planning. T...

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Commentary

Douglas GP, Gadabu OJ, Joukes S, Mumba S, McKay MV, et al.

2010-08-10 • PLOS Medicine

Journal Article

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Research

Tayler-Smith K, Tweya H, Harries AD, Schoutene E, Jahn A

2010-06-01 • Malawi Medical Journal

BACKGROUND
There is currently a dearth of knowledge on gender differences in mortality among patients on ART in Africa.

METHODS
Using data from the national ART monitori...

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Short Report

Harries AD, Jahn A, Ben-Smith A, Gadabu OJ, Douglas GP, et al.

2014-06-21 • Public Health Action

Journal Article

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Commentary

Harries AD, Zachariah R, van Oosterhout JJ, Reid SE, Hosseinipour MC, et al.

2010-01-01 • Lancet Infectious Diseases

Despite the enormous progress made in scaling up antiretroviral therapy (ART) in sub-Saharan Africa, many challenges remain, not least of which are the identification and management of p...

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Research

Kanyerere H, Harries AD, Tayler-Smith K, Jahn A, Zachariah R, et al.

2015-10-28 • Tropical Medicine and International Health

OBJECTIVES
Since 1985, Malawi has experienced a dual epidemic of HIV and tuberculosis (TB) which has been moderated recently by the advent of antiretroviral therapy (ART). The aim of...

Journal Article

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Review

Schouten EJ, Jahn A, Ben-Smith A, Makombe SD, Harries AD, et al.

2011-07-06 • Journal of the International AIDS Society

The number of people receiving antiretroviral treatment (ART) has increased considerably in recent years and is expected to continue to grow in the coming years. A major challenge is to ...

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Research

Harries AD, Jahn A, Zachariah R, Enarson D

2008-06-10 • PLOS Medicine

Science Portal

Viral suppression and HIV-1 drug resistance 1 year after pragmatic transitioning to dolutegravir first-line therapy in Malawi: a prospective cohort study

Emerging priorities for HIV service delivery

Decline in national tuberculosis notifications with national scale-up of antiretroviral therapy in Malawi

HIV and Tuberculosis in Prisons in Sub-Saharan Africa

The missed potential of CD4 and viral load testing to improve clinical outcomes for people living with HIV in lower-resource settings

A national survey of the impact of rapid scale-up of antiretroviral therapy on health-care workers in Malawi: effects on human resources and survival

Switching to second-line antiretroviral therapy in resource-limited settings: comparison of programmes with and without viral load monitoring

Decline in national tuberculosis notifications with national scale-up of antiretroviral therapy in Malawi (D/N include in MSF Pubs Dataset Analysis)

Vital Registration in Rural Africa: Is There a Way Forward to Report on Health Targets of the Millennium Development Goals?

Prevention of mother-to-child transmission of HIV and the health-related Millennium Development Goals: time for a public health approach

Scale-Up of ART in Malawi Has Reduced Case Notification Rates in HIV-Positive and HIV-Negative Tuberculosis

Decline in adverse outcomes and death in tuberculosis patients in Malawi: association with HIV interventions

Assessing the quality of data aggregated by antiretroviral treatment clinics in Malawi

Using touchscreen electronic medical record systems to support and monitor national scale-up of antiretroviral therapy in Malawi

Gender differences in retention and survival on antiretroviral therapy of HIV-1 infected adults in Malawi

Cohort analysis of antenatal care and delivery outcomes in pregnancy: a basis for improving maternal health

Diagnosis and management of antiretroviral-therapy failure in resource-limited settings in sub-Saharan Africa: challenges and perspectives

The rise and fall of tuberculosis in Malawi: associations with HIV infection and antiretroviral therapy

Antiretroviral drug supply challenges in the era of scaling up ART in Malawi

Adapting the DOTS framework for tuberculosis control to the management of non-communicable diseases in sub-Saharan Africa