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Showing 1 - 20 of 53 Items
Showing 1 - 20 of 53 Items
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Journal Article
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Research

Contribution of maternal adherence to the effect of multiple micronutrient supplementation during pregnancy: a systematic review and individual participant data meta-analysis

Smith ER, Gomes F, Adu-Afarwuah S, Aguayo VM, El Arifeen S,  et al.
2025-05-01 • Advances in Nutrition
2025-05-01 • Advances in Nutrition

Multiple micronutrient supplements (MMSs) in pregnancy reduces risk of infant low birthweight (LBW) and improves other maternal and infant outcom...

Journal Article
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Research

Prescribing practices in the treatment of wasting: secondary analysis from a randomised trial

Rattigan SM, Grantz KH, Hanson K, Langendorf C, Berthé F,  et al.
2024-02-26 • BMJ Nutrition, Prevention & Health
2024-02-26 • BMJ Nutrition, Prevention & Health
INTRODUCTION
Current guidelines for the outpatient treatment of severe acute malnutrition (SAM) recommend the provision of routine medications to all children at admission and prescr...
Journal Article
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Research

Effect of amoxicillin on the gut microbiome of children with severe acute malnutrition in Madarounfa, Niger: a retrospective metagenomic analysis of a placebo-controlled trial

Schwartz DJ, Langdon A, Sun X, Langendorf C, Berthé F,  et al.
2023-10-19 • Lancet Microbe
2023-10-19 • Lancet Microbe
BACKGROUND
Children with severe acute malnutrition are treated with antibiotics as outpatients. We aimed to determine the effect of 7 days of amoxicillin on acute and long-term chang...
Journal Article
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Research

Prognostic value of different anthropometric indices over different measurement intervals to predict mortality in 6–59-month-old children

Briend A, Myatt M, Berkley JA, Black RE, Boyd EM,  et al.
2023-06-01 • Public Health Nutrition
2023-06-01 • Public Health Nutrition
OBJECTIVE
To compare the prognostic value of mid-upper arm circumference (MUAC), weight-for-height Z-score (WHZ) and weight-for-age Z-score (WAZ) for predicting death over periods of...
Journal Article
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Review

Analysis of postdischarge interventions for children treated for moderate or severe wasting, growth faltering or failure, or edema

Bliznashka L, Rattigan SM, Sudfeld CR, Isanaka S
2023-05-01 • JAMA Network Open
2023-05-01 • JAMA Network Open
IMPORTANCE
Children treated for acute malnutrition remain at increased risk of relapse, infection, and mortality after programmatic recovery. Global guidelines for the management of ...
Journal Article
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Research

Anthropometric criteria for best-identifying children at high risk of mortality: a pooled analysis of twelve cohorts

Khara T, Myatt M, Sadler K, Bahwere P, Berkley JA,  et al.
2023-02-03 • Public Health Nutrition
2023-02-03 • Public Health Nutrition
OBJECTIVE
To understand which anthropometric diagnostic criteria best discriminate higher from lower risk of death in children and explore programme implications.

DESIGN
Journal Article
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Research

Cost-effectiveness of monthly follow-up for the treatment of uncomplicated severe acute malnutrition: An economic evaluation of a randomized controlled trial

Menzies NA, Berthé F, Hitchings MD, Aruna P, Hamza MA,  et al.
2022-12-09 • PLOS Global Public Health
2022-12-09 • PLOS Global Public Health
Severe acute malnutrition (SAM) is a major source of mortality for children in low resource settings. Alternative treatment models that improve acceptability and reduce caregiver burden ...
Journal Article
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Research

Impact and cost-effectiveness of rotavirus vaccination in Niger: a modelling study evaluating alternative rotavirus vaccines

Debellut F, Tang K, Clark A, Pecenka C, Assao B,  et al.
2022-10-05 • BMJ Open
2022-10-05 • BMJ Open
OBJECTIVES
To evaluate the cost-effectiveness of alternative rotavirus vaccines in Niger, using UNIVAC, a proportionate outcomes model.

SETTING
The study leverages globa...
Journal Article
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Research

Cost-effectiveness of routine versus indicated antibiotic therapy in the management of severe wasting in children

Isanaka S, Tang K, Berthé F, Grais RF, Pandya A
2022-08-03 • Cost Effectiveness and Resource Allocation
2022-08-03 • Cost Effectiveness and Resource Allocation
BACKGROUND
In the outpatient management of severe wasting, routine antibiotic therapy is recommended for all children upon admission regardless of whether clinical signs of infection...
Journal Article
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Research

Burden and risk factors for relapse following successful treatment of uncomplicated severe acute malnutrition in young children: Secondary analysis from a randomised trial in Niger

Bliznashka L, Grantz KH, Botton J, Berthé F, Garba S,  et al.
2022-07-21 • Maternal and Child Nutrition
2022-07-21 • Maternal and Child Nutrition
This study aimed to quantify the burden of relapse following successful treatment for uncomplicated severe acute malnutrition (SAM) and to identify associated risk factors in rural Niger...
Journal Article
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Research

Outpatient treatment of severe acute malnutrition: response to treatment with a reduced schedule of therapeutic food distribution

Isanaka S, Kodish SR, Berthé F, Alley I, Nackers F,  et al.
2017-04-12 • American Journal of Clinical Nutrition
2017-04-12 • American Journal of Clinical Nutrition
BACKGROUND
Community-based management of severe acute malnutrition (SAM) has been shown to be safe and cost-effective, but program coverage remains low. Treatment models that maintai...
Journal Article
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Research

Acceptability and utilization of a lipid-based nutrient supplement formulated for pregnant women in rural Niger: a multi-methods study

Isanaka S, Kodish SR, Mamaty AA, Guindo O, Zeilani M,  et al.
2019-07-01 • BMC Nutrition
2019-07-01 • BMC Nutrition
Background
In food insecure settings, it may be difficult for pregnant women to meet increased nutritional needs through traditional diets. A promising new strategy to fill nutrient...
Journal Article
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Letter

Amoxicillin for severe acute malnutrition in children

Isanaka S, Adehossi E, Grais RF
2016-07-14 • New England Journal of Medicine
2016-07-14 • New England Journal of Medicine
Journal Article
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Research

Estimating program coverage in the treatment of severe acute malnutrition: a comparative analysis of the validity and operational feasibility of two methods

Isanaka S, Hedt-Gauthier BL, Grais RF, Allen BGS
2018-07-03 • Population Health Metrics
2018-07-03 • Population Health Metrics
Many health programs can assess coverage using standardized cluster survey methods, but estimating the coverage of nutrition programs presents a special challenge due to low disease prev...
Journal Article
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Research

Conceptualizing factors impacting nutrition services coverage of treatment for acute malnutrition in children - an application of the Three Delays Model in Niger

Kodish SR, Allen BGS, Salou H, Schwendler TR, Isanaka S
2021-10-08 • Public Health Nutrition
2021-10-08 • Public Health Nutrition
OBJECTIVE
The Three Delays Model is a conceptual model traditionally used to understand contributing factors of maternal mortality. It posits that most barriers to health services ut...
Journal Article
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Research

Immunogenicity of an oral rotavirus vaccine administered with prenatal nutritional support in Niger: A cluster randomized clinical trial

Isanaka S, Garba S, Plikaytis BD, McNeal MM, Guindo O,  et al.
2021-08-10 • PLOS Medicine
2021-08-10 • PLOS Medicine
BACKGROUND
Nutritional status may play a role in infant immune development. To identify potential boosters of immunogenicity in low-income countries where oral vaccine efficacy is lo...
Journal Article
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Research

Malaria and nutritional status among children with severe acute malnutrition in Niger: a prospective cohort study

Oldenburg CE, Guerin PJ, Berthé F, Grais RF, Isanaka S
2018-09-14 • Clinical Infectious Diseases
2018-09-14 • Clinical Infectious Diseases
BACKGROUND
The relationship between malaria infection and nutritional status is complex. Previous studies suggest malaria may increase the incidence and severity of malnutrition, whi...
Conference Material
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Poster

Using MUAC as the sole anthropometric criterion for admission and discharge during outpatient treatment for Severe Acute Malnutrition : Niger Operational Experience

Isanaka S, Garba S, Cabrera ME, Rocaspana M
2021-05-18 • MSF Scientific Days International 2021: Research
2021-05-18 • MSF Scientific Days International 2021: Research
Journal Article
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Research

A feasibility study using mid-upper arm circumference as the sole anthropometric criterion for admission and discharge in the outpatient treatment for severe acute malnutrition

Garba S, Salou H, Nackers F, Ayouba A, Guindo O,  et al.
2021-08-12 • BMC Nutrition
2021-08-12 • BMC Nutrition
BACKGROUND
The World Health Organization recommends the use of a weight-for-height Z-score (WHZ) and/or mid-upper arm circumference (MUAC) as anthropometric criteria for the admissio...
Journal Article
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Research

Effectiveness of a monthly schedule of follow-up for the treatment of uncomplicated severe acute malnutrition in Sokoto, Nigeria: a cluster randomized crossover trial

Hitchings MD, Berthe F, Aruna P, Shehu I, Ali Hamza M,  et al.
2022-03-01 • PLOS Medicine
2022-03-01 • PLOS Medicine
BACKGROUND
Community-based management of severe acute malnutrition (SAM) involves weekly or biweekly outpatient clinic visits for clinical surveillance and distribution of therapeuti...