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Copyright © Médecins Sans Frontières
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Showing 1 - 20 of 162 Items
Showing 1 - 20 of 162 Items
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Journal Article
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Research

End of treatment and 12-month post-treatment outcomes in patients treated with all-oral regimens for rifampicin-resistant tuberculosis in Ukraine: a prospective cohort study

Fardhdiani V, Trush O, Lytvynenko N, Pylypchuk S, Terleeva Y,  et al.
2025-05-23 • PLOS Global Public Health
2025-05-23 • PLOS Global Public Health

The World Health Organization has called for operational research on all-oral shorter regimens for rifampin-resistant and multidrug-resistant forms of tuberculosis (RR/MDR-TB). We fol...

Journal Article
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Research

Enhancing tuberculosis (TB) case detection among hospitalized patients through lay health worker led screening: a before-and-after study in KwaZulu-Natal, South Africa

Bulti AB, Dumicho AY, Shigayeva A, Van Cutsem G, Steele SJ,  et al.
2025-04-23 • Scientific Reports
2025-04-23 • Scientific Reports

Tuberculosis (TB) among hospitalized patients is underdiagnosed. This study assessed systematic TB-screenin...

Journal Article
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Research

Development of machine learning algorithms to predict viral load suppression among HIV patients in Conakry (Guinea)

Yehadji D, Gray G, Vicente CA, Isaakidis P, Diallo A,  et al.
2025-03-19 • Frontiers in Artificial Intelligence
2025-03-19 • Frontiers in Artificial Intelligence

BACKGROUND

Viral load (VL) suppression is key to ending the global HIV epidemic, and predicting it is critical for healthcare providers and people living with H...

Journal Article
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Research

Bedaquiline resistance and treatment outcomes among patients with tuberculosis previously exposed to bedaquiline in India: A multicentric retrospective cohort study

Singla R, Khan S, Silsarma A, Chavan V, Mahajan R,  et al.
2025-03-13 • Clinical Infectious Diseases
2025-03-13 • Clinical Infectious Diseases

BACKGROUND

Bedaquiline (BDQ) resistance presents a critical challenge in the fight against tuberculosis (TB), particularly multidrug-resistant (MDR) strains. Th...

Journal Article
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Research

Characteristics of children and adolescents with multidrug-resistant and rifampicin-resistant tuberculosis and their association with treatment outcomes: a systematic review and individual participant data meta-analysis

Garcia-Prats AJ, Garcia-Cremades M, Cox V, Kredo T, Dunbar R,  et al.
2025-02-01 • Lancet Child and Adolescent Health
2025-02-01 • Lancet Child and Adolescent Health

BACKGROUND

There are few data on the treatment of children and adolescents with multidrug-resistant (MDR) or rifampicin-resistant (RR) tuberculosis, especially ...

Journal Article
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Letter

Sustained treatment success at 12 months for drug-resistant TB patients on concomitant bedaquiline-delamanid

Chavan V, Silsarma A, Mahajan R, Khan S, Singh P,  et al.
2025-02-01 • IJTLD OPEN
2025-02-01 • IJTLD OPEN
Journal Article
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Pre-Print

A comparison of acceptability of contraceptive vaginal rings, pills, and injectables among cisgender women in Kenya and Zimbabwe: protocol for a mixed-methods study

Polis CB, Obare FO, Bruce IV, Banda C, Haddad LB,  et al.
2024-12-20 • VeriXiv
2024-12-20 • VeriXiv

BACKGROUND

Expanding contraceptive options could better meet users’ diverse needs and preferences. Annovera® is a contraceptive vaginal ring that pro...

Conference Material
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Poster

12-month post-treatment outcomes of previously treated drug-resistant tuberculosis patients subsequently treated with concomitant bedaquiline and delamanid +/-carbapenem, in Mumbai, India

Chavan V, Silsarma A, Khan S, Singh P, Iyer A,  et al.
2024-11-08 • MSF Scientific Days Asia 2024
2024-11-08 • MSF Scientific Days Asia 2024
Journal Article
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Research

Treatment outcomes among patients with isoniazid mono-resistant tuberculosis in Mumbai, India: A retrospective cohort study

Khan S, Silsarma A, Mahajan R, Davuluri P, Sutar N,  et al.
2024-10-12 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
2024-10-12 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases

BACKGROUND

Tub...

Journal Article
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Research

Usability and acceptability of self-testing for hepatitis C virus exposure in a high-prevalence urban informal settlement in Karachi, Pakistan

Mazzilli S, Aslam MK, Akhtar J, Miazek M, Wailly Y,  et al.
2024-09-27 • BMC Infectious Diseases
2024-09-27 • BMC Infectious Diseases

BACKGROUND

Hepatitis C virus (HCV) antibody self-testing (HCVST) may help expand screening access and support HCV elimination efforts. Despite potential benefit...

Journal Article
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Research

Concomitant bedaquiline and delamanid therapy in patients with drug-resistant extra-pulmonary tuberculosis in Mumbai, India

Mongia H, Mamnoon F, Silsarma A, Mahajan R, Dalal A,  et al.
2024-04-01 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
2024-04-01 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
BACKGROUND
World Health Organization suggests concurrent bedaquiline-delamanid (BDQ-DLM) as part of individualised regimens for eligible patients with pulmonary drug-resistant tuberc...
Journal Article
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Research

Supporting re-engagement with HIV services after treatment interruption in South Africa: a mixed method program evaluation of MSF’s Welcome Service

Arendse KD, Walker C, Pfaff C, Lebelo K, Cassidy T,  et al.
2024-03-27 • Scientific Reports
2024-03-27 • Scientific Reports
Psychosocial challenges impact patients’ ability to remain on antiretroviral therapy lifelong, magnified by disorganized health-systems and healthcare worker (HCW) attitudes. To address ...
Journal Article
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Pre-Print

Enhancing tuberculosis (TB) diagnosis among hospitalized patients in KwaZulu-Natal, South Africa: a before-and-after study of a lay health worker-driven intervention

Bulti AB, Dumicho AY, Shigayeva A, van Cutsem G, Steele SJ,  et al.
2024-03-08 • Scientific Reports
2024-03-08 • Scientific Reports
BACKGROUND
Tuberculosis (TB) among hospitalized patients is underdiagnosed. This study assessed systematic TB-screening, followed by an enhanced TB-diagnostic package for hospitaliz...
Journal Article
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Research

Management of rifampicin-resistant tuberculosis in conflict-affected areas: The case of Iraq

Tesfahun HM, Al-Salihi L, Abdulkareem Al-Ani N, Mankhi AA, Mohammed A,  et al.
2024-01-19 • PLOS One
2024-01-19 • PLOS One
Since December 2019, the World Health Organization (WHO) has encouraged National Tuberculosis Programs to deprioritize the use of injectable-containing regimens and roll-out all-oral bed...
Journal Article
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Research

Prevalence and risk factors for hepatitis C virus infection in an informal settlement in Karachi, Pakistan

Alam R, Aslam K, Ahmed M, Isaakidis P
2023-09-20 • PLOS Global Public Health
2023-09-20 • PLOS Global Public Health
The burden of hepatitis C virus (HCV) infection in Pakistan is amongst the highest in the world. People living in slums are likely to be at high risk of infection. Here, we describe the ...
Journal Article
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Research

Clinical standards for drug-susceptible TB in children and adolescents

Chiang SS, Graham SM, Schaaf HS, Marais BJ, Sant’Anna CC,  et al.
2023-08-01 • International Journal of Tuberculosis and Lung Disease
2023-08-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
These clinical standards aim to provide guidance for diagnosis, treatment, and management of drug-susceptible TB in children and adolescents.

METHODS
Fifty-tw...
Journal Article
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Research

Facteurs associés à la létalité chez les patients hospitalisés pour le VIH avancé

Abdourahimi D, Yehadji D, Briskin E, Khine EM, Arias C,  et al.
2023-08-01 • Public Health Action
2023-08-01 • Public Health Action
CONTEXTE
Une unité soutenue par Médecins Sans Frontières (MSF) qui prend en charge les patients avec un VIH avancé à l’Hôpital National de Donka, Conakry, Guinée.

OBJECTIF
Journal Article
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Letter

Linezolid resistance in patients with drug-resistant TB

Vengurlekar D, Walker C, Mahajan R, Dalal A, Chavan VV,  et al.
2023-07-01 • International Journal of Tuberculosis and Lung Disease
2023-07-01 • International Journal of Tuberculosis and Lung Disease
Conference Material
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Slide Presentation

High prevalence of bedaquiline and linezolid resistance in extensively drug-resistant tuberculosis patients in a Médecins Sans Frontières clinic, Mumbai, India

Khan S, Silsarma A, Iyer AS, Galindo MA, Chavan VV,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Conference Material
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Abstract

High prevalence of bedaquiline and linezolid resistance in extensively drug-resistant tuberculosis patients in a Médecins Sans Frontières clinic, Mumbai, India

Khan S, Silsarma A, Iyer AS, Galindo MA, Chavan VV,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
INTRODUCTION
Bedaquiline (BDQ) and linezolid (LZD) are Group A drugs and form part of shorter and longer BDQ-based regimens under India’s National Tuberculosis (TB) Programme. A syst...