Showing 1 - 20 of 66 Items
Showing 1 - 20 of 66 Items
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Conference Material
|Slide Presentation
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024
Conference Material
|Abstract
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024
INTRODUCTION
Visceral leishmaniasis (VL) is a neglected tropical disease prevalent in populations affected by poverty, war, and famine. Without effective treatment, death is the norm...
Visceral leishmaniasis (VL) is a neglected tropical disease prevalent in populations affected by poverty, war, and famine. Without effective treatment, death is the norm...
Journal Article
|Review
2024-05-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2024-05-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Blood transfusion remains an important aspect of patient management in visceral leishmaniasis (VL). However, transfusion triggers considered are poorly understood. This review summarises...
Journal Article
|Research
2010-06-11 • PLOS One
2010-06-11 • PLOS One
Meningococcal meningitis outbreaks occur every year during the dry season in the "meningitis belt" of sub-Saharan Africa. Identification of the causative strain is crucial before launchi...
Journal Article
|Research
2013-11-13 • CPT: Pharmacometrics and Systems Pharmacology
2013-11-13 • CPT: Pharmacometrics and Systems Pharmacology
Pregnancy alters the pharmacokinetic properties of many antimalarial compounds. The objective of this study was to evaluate the pharmacokinetic properties of lumefantrine in pregnant and...
Journal Article
|Research
2005-12-01 • Lancet Infectious Diseases
2005-12-01 • Lancet Infectious Diseases
The state of Bihar in India carries the largest share of the world's burden of antimony-resistant visceral leishmaniasis. We analysed clinical studies done in Bihar with different treatm...
Journal Article
|Research
2006-05-29 • Vaccine
2006-05-29 • Vaccine
We conducted a study to assess the feasibility and the potential vaccine coverage of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban endemic neighbourhood o...
Journal Article
|Research
2011-05-31 • PLOS One
2011-05-31 • PLOS One
Sputum microscopy is the only diagnostic for tuberculosis (TB) available at peripheral levels of health service in resource-poor countries. Its sensitivity is reduced in high HIV-prevale...
Journal Article
|Research
2007-09-01 • International Journal of Tuberculosis and Lung Disease
2007-09-01 • International Journal of Tuberculosis and Lung Disease
SETTING: Urban health clinic, Nairobi. OBJECTIVE: To evaluate the impact on tuberculosis (TB) case detection and laboratory workload of reducing the number of sputum smears examined and ...
Journal Article
|Research
2012-01-01 • PLOS One
2012-01-01 • PLOS One
Abstract. Improved laboratory diagnosis is critical to reduce the burden of malaria in pregnancy. Peripheral blood smears appear less sensitive than Plasmodium falciparum histidine-rich ...
Journal Article
|Research
2018-09-14 • Clinical Infectious Diseases
2018-09-14 • Clinical Infectious Diseases
BACKGROUND
The relationship between malaria infection and nutritional status is complex. Previous studies suggest malaria may increase the incidence and severity of malnutrition, whi...
The relationship between malaria infection and nutritional status is complex. Previous studies suggest malaria may increase the incidence and severity of malnutrition, whi...
Journal Article
|Research
2008-04-14 • Lancet
2008-04-14 • Lancet
BACKGROUND: In sub-Saharan Africa in the 1990s, more than 600,000 people had epidemic meningococcal meningitis, of whom 10% died. The current recommended treatment by WHO is short-course...
Journal Article
|Research
2018-02-27 • Malaria Journal
2018-02-27 • Malaria Journal
BACKGROUND
In Niger, malaria transmission is markedly seasonal with most of the disease burden occurring in children during the rainy season. Seasonal malaria chemoprevention (SMC) w...
In Niger, malaria transmission is markedly seasonal with most of the disease burden occurring in children during the rainy season. Seasonal malaria chemoprevention (SMC) w...
Journal Article
|Research
2010-12-01 • International Journal of Tuberculosis and Lung Disease
2010-12-01 • International Journal of Tuberculosis and Lung Disease
SETTING
Although tuberculosis (TB) is a curable disease, it remains a major global health problem and an important cause of morbidity and mortality among vulnerable populations, incl...
Although tuberculosis (TB) is a curable disease, it remains a major global health problem and an important cause of morbidity and mortality among vulnerable populations, incl...
Journal Article
|Research
2006-04-01 • Tropical Medicine and International Health
2006-04-01 • Tropical Medicine and International Health
OBJECTIVE: To compare the cost-effectiveness of malaria treatment based on presumptive diagnosis with that of malaria treatment based on rapid diagnostic tests (RDTs). METHODS: We calcul...
Journal Article
|Research
2013-07-17 • Malaria Journal
2013-07-17 • Malaria Journal
BACKGROUND
Safety surveillance of widely used artemisinin-based combination therapy (ACT) is essential, but tolerability data in the over five years age group are largely anecdotal.<...
Safety surveillance of widely used artemisinin-based combination therapy (ACT) is essential, but tolerability data in the over five years age group are largely anecdotal.<...
Journal Article
|Research
2020-02-25 • BMC Medicine
2020-02-25 • BMC Medicine
BACKGROUND
The majority of Plasmodium falciparum malaria cases in Africa are treated with the artemisinin combination therapies artemether-lumefantrine (AL) and artesunate-amodiaquin...
The majority of Plasmodium falciparum malaria cases in Africa are treated with the artemisinin combination therapies artemether-lumefantrine (AL) and artesunate-amodiaquin...
Journal Article
|Research
2019-06-01 • Clinical Pharmacology & Therapeutics
2019-06-01 • Clinical Pharmacology & Therapeutics
Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub‐Saharan African children and may affect the pharmacology of antimalarial drugs....
Journal Article
|Research
2009-06-01 • Journal of Clinical Microbiology
2009-06-01 • Journal of Clinical Microbiology
Biological samples collected in refugee camps during an outbreak of hepatitis E were used to compare the accuracy of hepatitis E virus RNA amplification by real-time reverse transcriptio...
Journal Article
|Research
2009-10-27 • Malaria Journal
2009-10-27 • Malaria Journal
BACKGROUND: In areas where non-falciparum malaria is common rapid diagnostic tests (RDTs) capable of distinguishing malaria species reliably are needed. Such tests are often based on the...