Search Results | MSF Science Portal

Conference Material

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Poster

Akem TE, Schramm B, Akeen WW, Singh SN, Adimw M, et al.

2024-05-23 • Epicentre Scientific Day 2024

Conference Material

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Poster

Grandesso F, Ouedraogo P, Issakha Diar MS, Hilario JS, Kouassi F, et al.

2024-05-23 • Epicentre Scientific Day 2024

Journal Article

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Research

Caleo G, Lokuge K, Kardamanidis K, Greig J, Belava J, et al.

2024-04-25 • Global Health Action

BACKGROUND
There is a lack of empirical data on design effects (DEFF) for mortality rate for highly clustered data such as with Ebola virus disease (EVD), along with a lack of docume...

Journal Article

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Research

Nsio JM, Ardiet DL, Coulborn RM, Grellety E, Albela M, et al.

2023-01-01 • Lancet Infectious Diseases

BACKGROUND
In its earliest phases, Ebola virus disease's rapid-onset, high fever, and gastrointestinal symptoms are largely indistinguishable from other infectious illnesses. We aime...

MSF Ethics Review Board

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Standardized survey templates

Gerstl S, Grandesso F, Siddiqui R, Greig J, du Cros PAK, et al.

2022-10-25

Ce modèle doit être utilisé comme cadre pour écrire votre protocole d'enquête de mortalité contextualisée. Il a été pré-approuvé par le comité de révision éthique de MSF le 12 juillet 20...

MSF Ethics Review Board

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Standardized survey templates

Grandesso F, Gerstl S, Siddiqui R, Greig J, du Cros PAK, et al.

2022-10-25

Mortality Survey Protocol - standardised, MSF ERB approved, intersectional

This collection of files includes an overview of the whole process of conducting a mortality survey an...

Journal Article

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Research

Grandesso F, Allan M, Jean-Simon PSJ, Boncy J, Blake A, et al.

2013-10-11 • Epidemiology and Infection

SUMMARY Two community-based density case-control studies were performed to assess risk factors for cholera transmission during inter-peak periods of the ongoing epidemic in two Haitian u...

Journal Article

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Research

Allan M, Grandesso F, Pierre R, Magloire R, Coldiron ME, et al.

2015-09-03 • Epidemics

BACKGROUND
Cholera is caused by Vibrio cholerae, and is transmitted through fecal-oral contact. Infection occurs after the ingestion of the bacteria and is usually asymptomatic. In a...

Journal Article

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Research

Azman AS, Parker LA, Rumunu J, Tadesse F, Grandesso F, et al.

2016-11-01 • Lancet Global Health

BACKGROUND
Oral cholera vaccines represent a new effective tool to fight cholera and are licensed as two-dose regimens with 2-4 weeks between doses. Evidence from previous studies su...

Journal Article

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Research

Grandesso F, Hagerman A, Kamara S, Lam E, Checchi F, et al.

2006-07-01 • Tropical Medicine and International Health

OBJECTIVE: In 2004, Sierra Leone adopted artesunate plus amodiaquine as first-line antimalarial treatment. We evaluated the efficacy of this combination in Kailahun, where a previous stu...

Journal Article

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Commentary

Mbangombe M, Pezzoli L, Reeder B, Kabuluzi S, Msyamboza K, et al.

2018-06-01 • Bulletin of the World Health Organization

PROBLEM
With limited global supplies of oral cholera vaccine, countries need to identify priority areas for vaccination while longer-term solutions, such as water and sanitation infr...

Journal Article

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Research

De Beaudrap P, Nabasumba C, Grandesso F, Turyakira E, Schramm B, et al.

2011-05-18 • Malaria Journal

BACKGROUND
Malaria is a major public health problem, especially for children. However, recent reports suggest a decline in the malaria burden. The aim of this study was to assess the...

Journal Article

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Research

Grandesso F, Rafael F, Chipeta S, Alley I, Saussier C, et al.

2018-09-27 • Bulletin of the World Health Organization

OBJECTIVE
To evaluate vaccination coverage, identify reasons for non-vaccination and assess satisfaction with two innovative strategies for distributing second doses in an oral chole...

Journal Article

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Research

Piola P, Fogg C, Bajunirwe F, Biraro S, Grandesso F, et al.

2005-04-23 • Lancet

BACKGROUND: The six-dose regimen of artemether-lumefantrine is effective and is among combination therapies prioritised to replace antimalarials that no longer work in Africa. However, i...

Journal Article

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Research

Grandesso F, Guindo O, Woi-Messe LC, Makarimi R, Traore A, et al.

2018-01-25 • Malaria Journal

BACKGROUND
Malaria endemic countries need to assess efficacy of anti-malarial treatments on a regular basis. Moreover, resistance to artemisinin that is established across mainland S...

Journal Article

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Research

Pasetto D, Finger F, Camacho A, Grandesso F, Cohuet S, et al.

2018-05-16 • PLoS Computational Biology

Computational models of cholera transmission can provide objective insights into the course of an ongoing epidemic and aid decision making on allocation of health care resources. However...

Protocol

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Research Protocol

Denoeud-Ndam L, Dicko A, Baudin E, Guindo O, Grandesso F, et al.

2015-06-12 • BMC Infectious Diseases

Malnutrition and malaria frequently coexist in sub-Saharan African countries. Studies on efficacy of antimalarial treatments usually follow the WHO standardized protocol in which severel...

Journal Article

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Research

Luquero FJ, Rondy M, Boncy J, Munger A, Mekaoui H, et al.

2016-03-01 • Emerging Infectious Diseases

The 2010 cholera epidemic in Haiti was one of the largest cholera epidemics ever recorded. To estimate the magnitude of the death toll during the first wave of the epidemic, we retrospec...

Journal Article

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Letter

Peyraud N, Rafael F, Parker LA, Quere M, Alcoba G, et al.

2017-02-05 • Lancet Global Health

Journal Article

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Research

Grandesso F, Bachy C, Donam I, Ntambi J, Habimana J, et al.

2006-05-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene

We report two 28-day in-vivo antimalarial efficacy studies carried out in the urban centres of Bongor and Koumra, southern Chad. We assess chloroquine (CQ), sulfadoxine-pyrimethamine (SP...

Science Portal

Seasonal malaria chemoprevention coverage survey for children 3 months –8 years in Aweil, South Sudan, 2022

Les medicaments de la CPS sous la loupe

Methodological issues of retrospective surveys for measuring mortality of highly clustered diseases: case study of the 2014–16 Ebola outbreak in Bo District, Sierra Leone

Differential symptomology of possible and confirmed Ebola virus disease infection in the Democratic Republic of the Congo: a retrospective cohort study

MSF ERB Enquête rétrospective sur la mortalité

Standardised mortality surveys

Risk factors for cholera transmission in Haiti during inter-peak periods: insights to improve current control strategies from two case-control studies

High-resolution spatial analysis of cholera patients reported in Artibonite department, Haiti in 2010–2011

Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study

Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone

Oral cholera vaccine in cholera prevention and control, Malawi

Heterogeneous decrease in malaria prevalence in children over a six-year period in south-western Uganda

Oral cholera vaccination in hard-to-reach communities, Lake Chilwa, Malawi

Supervised versus unsupervised intake of six-dose artemether-lumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trial

Efficacy of artesunate-amodiaquine, dihydroartemisinin-piperaquine and artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Maradi, Niger

Near real-time forecasting for cholera decision making in Haiti after Hurricane Matthew

A multi-center, open-label trial to compare the efficacy and pharmacokinetics of Artemether-Lumefantrine in children with severe acute malnutrition versus children without severe acute malnutrition: study protocol for the MAL-NUT study

Mortality rates during cholera epidemic, Haiti, 2010-2011

An Epidemic of Dystonic Reactions in Central Africa

Efficacy of chloroquine, sulfadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria among children under five in Bongor and Koumra, Chad