Search Results | MSF Science Portal

Journal Article

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Research

Cornell M, Grimsrud A, Fairall L, Fox MP, van Cutsem G, et al.

2010-09-10 • AIDS

OBJECTIVE: Little is known about the temporal impact of the rapid scale-up of large antiretroviral therapy (ART) services on programme outcomes. We describe patient outcomes [mortality, ...

Journal Article

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Research

Cornell M, Technau KG, Fairall L, Wood R, Moultrie H, et al.

2009-09-01 • South African Medical Journal

OBJECTIVES: To introduce the combined South African cohorts of the International epidemiologic Databases to Evaluate AIDS Southern Africa (IeDEA-SA) collaboration as reflecting the South...

Journal Article

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Short Report

Nelson AM, Maritz J, Giddy J, Frigati L, Rabie H, et al.

2015-04-28 • Southern African Journal of HIV medicine

Journal Article

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Research

Gsponer T, Weigel R, Davies MA, Bolton C, Moultrie H, et al.

2012-09-17 • Pediatrics

BACKGROUND
Poor growth is an indication for antiretroviral therapy (ART) and a criterion for treatment failure. We examined variability in growth response to ART in 12 programs in Ma...

Journal Article

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Research

Boulle AM, Schomaker M, May MT, Hogg RS, Shepherd B, et al.

2014-09-09 • PLOS Medicine

BACKGROUND
High early mortality in patients with HIV-1 starting antiretroviral therapy (ART) in sub-Saharan Africa, compared to Europe and North America, is well documented. Longer-t...

Journal Article

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Research

Hoffman CJ, Schomaker M, Fox MP, Mutevedzi, Giddy J, et al.

2013-01-22 • Journal of Acquired Immune Deficiency Syndromes (1999)

In many resource-limited settings monitoring of combination antiretroviral therapy (cART) is based on the current CD4 count, with limited access to HIV RNA tests or laboratory diagnostic...

Journal Article

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Research

Fenner L, Brinkhof MW, Keiser O, Weigel R, Cornell M, et al.

2010-08-01 • Journal of Acquired Immune Deficiency Syndromes (1999)

BACKGROUND: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in chi...

Journal Article

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Research

Schomaker M, Leroy V, Wolfs T, Technau KG, Renner L, et al.

2016-06-24 • International Journal of Epidemiology

Background: There is limited knowledge about the optimal timing of antiretroviral treatment initiation in older children and adolescents. Methods: A total of 20 576 antiretroviral treatm...

Journal Article

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Research

Nelson AM, Cassidy T, Duran LT, Cox V, Wedderburn C, et al.

2022-01-14 • PLOS One

BACKGROUND
Despite the reduction of HIV mother-to-child transmission, there are concerns regarding transmission rate in the breastfeeding period. We describe the routine uptake of 6 ...

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Research

Schomaker M, Davies A, Malateste K, Renner L, Sawry S, et al.

2015-10-16 • Epidemiology

Journal Article

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Research

Johnson LF, Mossong J, Dorrington R, Schomaker M, Hoffman CJ, et al.

2013-04-09 • PLOS Medicine

Few estimates exist of the life expectancy of HIV-positive adults receiving antiretroviral treatment (ART) in low- and middle-income countries. We aimed to estimate the life expectancy o...

Journal Article

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Research

Koller M, Fatti G, Chi BH, Keiser O, Hoffman CJ, et al.

2015-07-07 • Journal of Acquired Immune Deficiency Syndromes (1999)

Journal Article

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Research

Cornell M, Schomaker M, Garone DB, Giddy J, Hoffmann CJ, et al.

2012-09-04 • PLOS Medicine

Background: Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood. We examined the magnitude of and risk factors for g...

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Commentary

Apolisi I, Mema N, Tyeku N, Beko B, Memani B, et al.

2022-03-01 • Lancet Respiratory Medicine

Journal Article

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Research

Salazar-Vizcaya L, Keiser O, Technau KG, Davies MA, Haas AD, et al.

2014-10-23 • AIDS

OBJECTIVES
Many paediatric antiretroviral therapy (ART) programmes in Southern Africa rely on CD4⁺ to monitor ART. We assessed the benefit of replacing CD4⁺ by viral load monitoring....

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Research

Davies MA, Boulle AM, Technau KG, Eley B, Moultrie H, et al.

2012-09-01 • Tropical Medicine and International Health

OBJECTIVES
To determine the improvement in positive predictive value of immunological failure criteria for identifying virological failure in HIV-infected children on antiretroviral ...

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Research

Davies MA, Moultrie H, Eley B, Rabie H, van Cutsem G, et al.

2011-03-01 • Journal of Acquired Immune Deficiency Syndromes (1999)

With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determ...

Journal Article

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Research

Cornell M, Johnson LF, Schomaker M, Tanser F, Maskew M, et al.

2015-08-03 • Lancet HIV

BACKGROUND
As access to antiretroviral therapy (ART) expands, increasing numbers of older patients will start treatment and need specialised long-term care. However, the effect of ag...

Journal Article

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Research

Davies MA, Keiser O, Technau KG, Eley B, Rabie H, et al.

2009-10-01 • South African Medical Journal

OBJECTIVES: To assess paediatric antiretroviral treatment (ART) outcomes and their associations from a collaborative cohort representing 20% of the South African national treatment progr...

Journal Article

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Commentary

Stinson K, Giddy J, Cox V, Burton R, Ibeto M, et al.

2014-03-05 • Southern African Journal of HIV medicine

Science Portal

Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007

Monitoring the South African National Antiretroviral Treatment Programme, 2003-2007: the IeDEA Southern Africa collaboration

HIV testing and antiretroviral therapy initiation at birth: Views from a primary care setting in Khayelitsha

Variability of growth in children starting antiretroviral treatment in Southern Africa

Mortality in patients with HIV-1 infection starting antiretroviral therapy in South Africa, Europe, or North America: a collaborative analysis of prospective studies

CD4 count slope and mortality in HIV-infected patients on antiretroviral therapy: multicohort analysis from South Africa

Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa

Optimal Timing of Antiretroviral Treatment Initiation in HIV-Positive Children and Adolescents: a Multiregional Analysis from Southern Africa, West Africa and Europe

An analysis of the HIV testing cascade of a group of HIV-exposed infants from birth to 18 months in peri-urban Khayelitsha, South Africa

Growth and mortality outcomes for different antiretroviral therapy initiation criteria in children aged 1-5 years: a causal modelling analysis

Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies

Risk charts to guide targeted HIV-1 viral load monitoring of ART: development and validation in patients from resource-limited settings

Gender differences in survival among adult patients starting antiretorivral therapy in South Africa: a multicentre cohort study

Supporting families with tuberculosis during COVID-19 in Khayelithsa, South Africa

Viral load versus CD4⁺ monitoring and 5-year outcomes of antiretroviral therapy in HIV-positive children in Southern Africa: a cohort-based modelling study

The role of targeted viral load testing in diagnosing virological failure in children on antiretroviral therapy with immunological failure

Virologic failure and second-line antiretroviral therapy in children in South Africa--the IeDEA Southern Africa collaboration

Age in antiretroviral therapy programmes in South Africa: a retrospective, multicentre, observational cohort study

Outcomes of the South African National Antiretroviral Treatment Programme for children: the IeDEA Southern Africa collaboration

Reflections on a decade of delivering PMTCT in Khayelitsha, South Africa