Search Results | MSF Science Portal

Journal Article

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Commentary

Tayler-Smith K, Zachariah R, Manzi M, Kizito W, Vandenbulcke A, et al.

2011-08-10 • Tropical Medicine and International Health

Journal Article

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Research

Nackers F, Huerga H, Espie E, Aloo AO, Bastard M, et al.

2012-03-12 • PLOS One

Good adherence to treatment is crucial to control tuberculosis (TB). Efficiency and feasibility of directly observed therapy (DOT) under routine program conditions have been questioned. ...

Journal Article

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Research

Yakhelef N, Audibert M, Varaine FFV, Chakaya JM, Sitienei J, et al.

2014-05-14 • International Journal of Tuberculosis and Lung Disease

SETTING
In 2007, the World Health Organization recommended introducing rapid Mycobacterium tuberculosis culture into the diagnostic algorithm of smear-negative pulmonary tuberculosis...

Journal Article

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Editorial

Zachariah R, Stewart AG, Chakaya JM, Teck R, Khogali MA, et al.

2022-04-11 • International Journal of Environmental Research and Public Health

Journal Article

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Research

Subramanian S, Gakunga R, Kibachio J, Gathecha G, Edwards P, et al.

2018-01-05 • PLOS One

The prevalence of non-communicable diseases (NCDs) is rising in low- and middle-income countries, including Kenya, disproportionately to the rest of the world. Our objective was to quant...

Journal Article

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Review

Zumla A, Abubakar I, Raviglione M, Hoelscher M, Ditui L, et al.

2012-04-03 • Journal of Infectious Diseases

Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short cour...

Journal Article

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Research

Migliori GB, Tiberi S, Zumla A, Petersen E, Chakaya JM, et al.

2020-02-01 • International Journal of Infectious Diseases

The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at provid...

Journal Article

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Research

Zachariah R, Reid AJ, Srinath S, Chakaya JM, Legins K, et al.

2011-11-01 • International Journal of Tuberculosis and Lung Disease

Very limited operational research (OR) emerges from programme settings in low-income countries where the greatest burden of disease lies. The price paid for this void includes a lack of ...

Journal Article

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Commentary

Migliori GB, Marx FM, Ambrosino N, Zampogna E, Schaaf HS, et al.

2021-10-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
Increasing evidence suggests that post-TB lung disease (PTLD) causes significant morbidity and mortality. The aim of these clinical standards is to provide guidance on the...

Journal Article

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Review

McNerney R, Maeurer M, Abubakar I, Marais BJ, McHugh TD, et al.

2012-04-10 • Journal of Infectious Diseases

Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to...

Journal Article

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Review

Lienhardt C, Lonnroth K, Menzies D, Balasegaram M, Chakaya JM, et al.

2016-03-02 • PLOS Medicine

Christian Lienhardt and colleagues describe the research efforts needed to end the global tuberculosis epidemic by 2035.

Journal Article

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Commentary

Zumla A, Chakaya JM, Hoelscher M, Ntoumi F, Rustomjee R, et al.

2015-07-17 • Nature Reviews Drug Discovery

Journal Article

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Research

Huerga H, Varaine FFV, Okwaro E, Bastard M, Ardizzoni E, et al.

2012-12-19 • PLOS One

BACKGROUND
The 2007 WHO algorithm for diagnosis of smear-negative pulmonary tuberculosis (PTB) including Mycobacterium tuberculosis (MTB) culture was evaluated in a HIV prevalent are...

Journal Article

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Research

Wahome E, Makori L, Gikera M, Chakaya JM, Edginton ME, et al.

2013-12-21 • Public Health Action

SETTING
Kenyatta National Hospital (KNH), Nairobi, Ken-ya, a large referral and teaching hospital.

OBJECTIVE
1) To document tuberculosis (TB) case notification rates and...

Journal Article

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Commentary

Zachariah R, Ford NP, Maher D, Bissell K, Van der Bergh R, et al.

2012-02-09 • Lancet Infectious Diseases

Operational research in low-income countries has a key role in filling the gap between what we know from research and what we do with that knowledge-the so-called know-do gap, or impleme...

Science Portal

Antiretroviral treatment uptake and attrition among HIV-positive patients with tuberculosis in Kibera, Kenya

Adherence to self-administered tuberculosis treatment in a high HIV-prevalence setting: a cross-sectional survey in Homa Bay, Kenya

Is introducing rapid culture in the diagnostic algorithm of smear-negative tuberculosis cost-effective?

The structured operational research and training initiative for strengthening health systems to tackle antimicrobial resistance and improve public health in low-and-middle income countries

Cost and affordability of non-communicable disease screening, diagnosis and treatment in Kenya: Patient payments in the private and public sectors

Drug-Resistant Tuberculosis--Current dilemmas, unanswered questions, challenges, and priority needs

MDR/XDR-TB management of patients and contacts: challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network

Building leadership capacity and future leaders in operational research in low-income countries: why and how?

Clinical standards for the assessment, management and rehabilitation of post-TB lung disease

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities

Translational Research for Tuberculosis Elimination: Priorities, Challenges, and Actions

Towards host-directed therapies for tuberculosis

Performance of the 2007 WHO Algorithm to diagnose Smear-negative Pulmonary Tuberculosis in a HIV prevalent setting

Tuberculosis treatment outcomes among hospital workers at a public teaching and national referral hospital in Kenya

Is operational research delivering the goods? The journey to success in low-income countries