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Copyright © Médecins Sans Frontières
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Showing 1 - 14 of 14 Items
Showing 1 - 14 of 14 Items
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Journal Article
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Research

Field evaluation of validity and feasibility of Pan-Lassa rapid diagnostic test for Lassa fever in Abakaliki, Nigeria: a prospective diagnostic accuracy study

Elsinga J, Sunyoto T, di Stefano L, Giorgetti PF, Kyi HA,  et al.
2024-09-01 • Lancet Infectious Diseases
2024-09-01 • Lancet Infectious Diseases
BACKGROUND
Lassa fever is a viral haemorrhagic fever with few options for diagnosis and treatment; it is also under-researched with knowledge gaps on its epidemiology. A point-of-car...
Conference Material
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Poster

Validity and feasibility of a Pan-Lassa rapid diagnostic test for Lassa fever in Abakaliki, Nigeria: a field evaluation

Elsinga J, Sunyoto T, Di Stefano L, Giorgetti PF, Kyi HA,  et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024
Conference Material
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Poster

Specificity and sensitivity of Tetanos Quick Stick: prospective evaluation, Port-au-Prince, Haiti

Obach D, Fares K, Woolley SC, Jean-Louis C, Denis O,  et al.
2022-05-09 • MSF Scientific Days International 2022
2022-05-09 • MSF Scientific Days International 2022
Journal Article
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Research

Errors generated by a point-of-care CD4+ T-lymphocyte analyser: a retrospective observational study in nine countries

Fajardo E, Metcalf CJ, Piriou E, Gueguen M, Maman D,  et al.
2015-06-25 • Bulletin of the World Health Organization
2015-06-25 • Bulletin of the World Health Organization
OBJECTIVE
To estimate the proportion of invalid results generated by a CD4+ T-lymphocyte analyser used by Médecins Sans Frontières (MSF) in field projects and identify factors associ...
Journal Article
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Commentary

Viewpoint: Why do we need a point-of-care CD4 test for low-income countries?

Zachariah R, Reid SE, Chaillet P, Massaquoi M, Schouten EJ,  et al.
2010-11-02 • Tropical Medicine and International Health
2010-11-02 • Tropical Medicine and International Health
In this paper, we discuss the reasons why we urgently need a point-of-care (POC) CD4 test, elaborate the problems we have experienced with the current technology which hampers CD4-count ...
Journal Article
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Commentary

Ensuring on-site Ebola patient monitoring and follow-up: development of a laboratory structure embedded in an Ebola treatment center

Williams A, Amand M, Van der Bergh R, Antierens A, Chaillet P
2019-06-24 • Disaster Medicine and Public Health Preparedness
2019-06-24 • Disaster Medicine and Public Health Preparedness
The capacity to rapidly distinguish Ebola virus disease from other infectious diseases and to monitor biochemistry and viremia levels is crucial to the clinical management of suspected E...
Journal Article
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Review

Diagnosis and management of Ebola samples in the laboratory

de la Vega MA, Bello A, Chaillet P, Kobinger GP
2016-05-13 • Expert Review of Anti-Infective Therapy
2016-05-13 • Expert Review of Anti-Infective Therapy
The magnitude of the 2014–2016 West African Ebola virus outbreak has highlighted the importance of immediate and rapid deployment of control measures in affected areas. While many prophy...
Journal Article
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Research

Better care for babies: the added value of a modified reverse syphilis testing algorithm for the treatment of congenital syphilis in a maternity Hospital in Central African Republic

Ogundipe OF, Van der Bergh R, Thierry B, Takarinda KC, Muller CP,  et al.
2019-08-15 • BMC Pediatrics
2019-08-15 • BMC Pediatrics
BACKGROUND:
In high syphilis prevalence settings, the syphilis testing and treatment strategy for mothers and newborns must be tailored to balance the risk of over treatment against...
Journal Article
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Research

Feasibility of Xpert Ebola Assay in Médecins Sans Frontières Ebola Program, Guinea

Van der Bergh R, Chaillet P, Sow MS, Amand M, van Vyve C,  et al.
2016-02-01 • Emerging Infectious Diseases
2016-02-01 • Emerging Infectious Diseases
Rapid diagnostic methods are essential in control of Ebola outbreaks and lead to timely isolation of cases and improved epidemiologic surveillance. Diagnosis during Ebola outbreaks in We...
Protocol
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Research Protocol

Multi-site evaluation of HIV testing algorithms

Kosack CS, Page AL, Shanks L, Chaillet P, Beelaert G,  et al.
2018-07-01
2018-07-01
Objectives
3.1 Primary objective
 To evaluate the overall and site-specific performance of the diagnostic algorithm performed at 6
MSF African program sites (i.e. using R...
Conference Material
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Poster

Outbreak of ESBL Klebsiella pneumoniae in a maternity unit in Central African Republic

Gil Cuesta J, Thallinger M, Antierens A, Caluwaerts A, Chaillet P,  et al.
2018-05-14 • MSF Scientific Days International 2018
2018-05-14 • MSF Scientific Days International 2018
Journal Article
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Research

Evaluation of four rapid tests for diagnosis and differentiation of HIV-1 and HIV-2 infections in Guinea-Conakry, West Africa

Chaillet P, Tayler-Smith K, Zachariah R, Duclos N, Moctar D,  et al.
2010-09-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2010-09-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
With both HIV-1 and HV-2 prevalent in Guinea-Conakry, accurate diagnosis and differentiation is crucial for treatment purposes. Thus, four rapid HIV tests were evaluated for their HIV-1 ...
Journal Article
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Research

The Partec CyFlow Counter could provide an option for CD4+ T-cell monitoring in the context of scaling-up antiretroviral treatment at the district level in Malawi

Fryland M, Chaillet P, Zachariah R, Barnaba A, Bonte L,  et al.
2006-10-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2006-10-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
A study was conducted in rural Malawi to verify (a) whether the Partec CyFlow Counter((R)) for CD4+ T-cell lymphocyte counting in HIV-positive individuals could be introduced into a dist...
Journal Article
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Research

Prospective evaluation of the diagnostic accuracy of dried blood spots from finger-prick for the determination of HIV-1 viral load with the NucliSENS Easy-Q HIV-1 v2.0 in Malawi

Farjardo E, Metcalf CJ, Chaillet P, Aleixo L, Pannus P,  et al.
2014-05-01 • Journal of Clinical Microbiology
2014-05-01 • Journal of Clinical Microbiology
HIV-1 viral load (VL) testing is not widely available in resource-limited settings. Use of finger-prick dried blood spot (FP-DBS) samples could remove barriers related to sample collecti...