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Copyright © Médecins Sans Frontières
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Showing 1 - 5 of 5 Items
Showing 1 - 5 of 5 Items
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Journal Article
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Research

Drug resistance in Plasmodium falciparum from the Chittagong Hill Tracts, Bangladesh

van den Broek IVF, van der Wardt S, Talukder L, Chakma S, Brockman A,  et al.
2004-06-01 • Tropical Medicine and International Health
2004-06-01 • Tropical Medicine and International Health
OBJECTIVE: To assess the efficacy of antimalarial treatment and molecular markers of Plasmodium falciparum resistance in the Chittagong Hill Tracts of Bangladesh. METHODS: A total of 203...
Journal Article
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Research

Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites

Imwong M, Snounou G, Pukrittayakamee S, Tanomsing N, Kim JH,  et al.
2007-04-01 • Journal of Infectious Diseases
2007-04-01 • Journal of Infectious Diseases
BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudesce...
Journal Article
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Research

Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites

Anderson TJC, Nair SA, Sudimack D, Williams JT, Mayxay M,  et al.
2005-12-01 • Molecular Biology and Evolution
2005-12-01 • Molecular Biology and Evolution
Loci targeted by directional selection are expected to show elevated geographical population structure relative to neutral loci, and a flurry of recent papers have used this rationale to...
Journal Article
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Research

Selection strength and hitchhiking around two anti-malarial resistance genes

Nash D, Nair SA, Mayxay M, Newton PN, Guthmann JP,  et al.
2005-06-02 • Proceedings. Biological sciences / The Royal Society
2005-06-02 • Proceedings. Biological sciences / The Royal Society
Neutral mutations may hitchhike to high frequency when they are situated close to sites under positive selection, generating local reductions in genetic diversity. This process is though...
Journal Article
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Research

Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant plasmodium falciparum distributions in Southeast Asia

Grist EP, Fleqq JA, Humphreys G, Mas IS, Anderson TJC,  et al.
2016-10-24 • International Journal of Health Geographics
2016-10-24 • International Journal of Health Geographics
BACKGROUND
Artemisinin-resistant Plasmodium falciparum malaria parasites are now present across much of mainland Southeast Asia, where ongoing surveys are measuring and mapping their...