Search Results | MSF Science Portal

Journal Article

|

Research

Larsson L, Calderwood CJ, Marambire ET, Held K, Banze D, et al.

2025-04-28 • Clinical Infectious Diseases

BACKGROUND

Studies have demonstrated an inverse log-linear relationship between body mass index (BMI) and tuberculosis incidence. However, a person’s BMI is dyn...

Journal Article

|

Research

Melingui BF, Basant J, Taguebue Jv, Massom DM, Leroy Terquem E, et al.

2024-11-03 • Journal of Tropical Medicine

OBJECTIVES

Chest x‐ray (CXR) plays an important role in childhood tuberculosis (TB) diagnosis, but access to quality CXR remains a major challenge in resource‐l...

Journal Article

|

Research

Ingelbeen B, Cumbane V, Mandlate F, Barbé B, Nhachungue SM, et al.

2024-08-05 • PLOS Global Public Health

In sub-Saharan Africa, reported COVID-19 numbers have been lower than anticipated, even when considering populations’ younger age. The extent to which risk factors, established in ind...

Conference Material

|

Poster

Ribes M, Atumane A, Adamuge M, Transval L, Intamo T, et al.

2024-05-03 • MSF Paediatric Days 2024

Journal Article

|

Research

d’Elbée M, Harker M, Mafirakureva N, Nanfuka M, Nguyet MHTN, et al.

2024-03-21 • eClinicalMedicine

Journal Article

|

Research

Wobudeya E, Nanfuka M, Ton Nu Nguyet MH, Taguebue JV, Moh R, et al.

2024-03-21 • ACG Case Reports Journal

BACKGROUND
Childhood tuberculosis (TB) remains underdiagnosed largely because of limited awareness and poor access to all or any of specimen collection, molecular testing, clinical e...

Journal Article

|

Review

Ruef M, Emonet S, Merglen A, Dewez JE, Obama BM, et al.

2024-03-11 • eClinicalMedicine

BACKGROUND
The increasing resistance of Enterobacterales to third-generation cephalosporins and carbapenems in sub-Saharan Africa (SSA) is a major public health concern. We did a sys...

Journal Article

|

Review

Kowalski M, Minka Obama B, Catho G, Dewez JE, Merglen A, et al.

2024-03-08 • eClinicalMedicine

BACKGROUND
The burden of antimicrobial resistance (AMR) has been estimated to be the highest in sub-Saharan Africa (SSA). The current study estimated the proportion of drug-resistant...

Journal Article

|

Research

Melingui BF, Leroy-Terquem E, Palmer M, Taguebue JV, Wachinou AP, et al.

2024-02-01 • IJTLD OPEN

BACKGROUND
Chest X-ray (CXR) interpretation is challenging for the diagnosis of paediatric TB. We assessed the performance of a three half-day CXR training module for healthcare work...

Journal Article

|

Research

Lissouba P, Rücker SCM, Otieno LA, Akatukwasa C, Xulu S, et al.

2023-11-30 • BMJ Open

OBJECTIVES
Evidence on the acceptability of urine-based assays for tuberculosis (TB) diagnosis among patients remains limited. We sought to describe patients’ experiences and percept...

Journal Article

|

Research

Joshi B, De Lima YV, Massom DM, Kaing S, Banga MF, et al.

2023-10-11 • PLOS Global Public Health

Decentralizing childhood tuberculosis services, including diagnosis, is now recommended by the WHO and could contribute to increasing tuberculosis detection in high burden countries. How...

Conference Material

|

Abstract

Natukunda N

2023-06-08 • Epicentre Scientific Day Paris 2023

BACKGROUND
Childhood tuberculosis is underdiagnosed at low-level healthcare settings because of poor access to specimen collection, rapid molecular testing, clinical evaluation and c...

Conference Material

|

Video

Natukunda N

2023-06-08 • Epicentre Scientific Day Paris 2023

Journal Article

|

Research

Loarec A, Gutierrez AG, Muvale G, Couto AM, Nguyen AP, et al.

2023-03-30 • Health Science Reports

BACKGROUND AND AIMS
Hepatitis C (HCV) programs face challenges, especially linked to key populations to achieve World Health Organization (WHO) goals of eliminating hepatitis. Médeci...

Journal Article

|

Research

Marcy O, Wobudeya E, Font H, Vessière A, Chabala C, et al.

2023-03-01 • Lancet Infectious Diseases

BACKGROUND
Tuberculosis diagnosis might be delayed or missed in children with severe pneumonia because this diagnosis is usually only considered in cases of prolonged symptoms or ant...

Journal Article

|

Research

Huerga H, Bastard M, Lubega AV, Akinyi M, Antabak NT, et al.

2023-01-01 • Lancet Global Health

BACKGROUND
Development of rapid biomarker-based tests that can diagnose tuberculosis using non-sputum samples is a priority for tuberculosis control. We aimed to compare the diagnost...

Journal Article

|

Research

Zheng Q, Luquero FJ, Ciglenecki I, Wamala JF, Abubakar A, et al.

2022-09-01 • International Journal of Infectious Diseases

BACKGROUND
Cholera remains a public health threat but is inequitably distributed across sub-Saharan Africa. Lack of standardized reporting and inconsistent outbreak definitions limit...

Journal Article

|

Research

Decroo T, Rasschaert F, Telfer B, Remartinez D, Laga M, et al.

2013-07-30 • International Health

In sub-Saharan Africa models of care need to adapt to support continued scale up of antiretroviral therapy (ART) and retain millions in care. Task shifting, coupled with community partic...

Conference Material

|

Abstract

Lissouba P, Huerga H, Rucker C

2021-06-10 • Epicentre Scientific Day Paris 2021

BACKGROUND
The novel point-of-care urine-based FujiLAM test is promising for diagnosis of tuberculosis. We assessed the diagnostic yield of FujiLAM in HIV patients and the feasibilit...

Conference Material

|

Abstract

Arago M, Mangue M, Cumbi N, Zamudio AG, Loarec A, et al.

2021-05-20 • MSF Scientific Days International 2021: Innovation

WHAT CHALLENGE OR OPPORTUNITY DID YOU TRY TO ADDRESS? WERE EXISTING SOLUTIONS NOT AVAILABLE OR NOT GOOD ENOUGH?
Ototoxicity is an unfortunate side-effect of second-line injectable dr...

Science Portal

Body mass index trajectories and association with tuberculosis risk in a cohort of household contacts in Southern Africa

Implementation of digital chest radiography for childhood tuberculosis diagnosis at district hospital level in six high tuberculosis burden and resources limited countries

Mild and moderate COVID-19 during Alpha, Delta and Omicron pandemic waves in urban Maputo, Mozambique, December 2020-March 2022: A population-based surveillance study

Knowledge, attitudes and practices on noma among health practitioners in Zambezia province, Mozambique

Cost-effectiveness and budget impact of decentralising childhood tuberculosis diagnosis in six high tuberculosis incidence countries: a mathematical modelling study

Effect of decentralising childhood tuberculosis diagnosis to primary health centre versus district hospital levels on disease detection in children from six high tuberculosis incidence countries: an operational research, pre-post intervention study

Carriage of third-generation cephalosporin-resistant and carbapenem-resistant Enterobacterales among children in sub-Saharan Africa: a systematic review and meta-analysis

Antimicrobial resistance in Enterobacterales infections among children in sub-Saharan Africa: a systematic review and meta-analysis

Evaluation of a short training course of chest X-ray interpretation for the diagnosis of paediatric TB

Experiences and perceptions of urine sampling for tuberculosis testing among HIV patients: a multisite qualitative descriptive study

Acceptability of decentralizing childhood tuberculosis diagnosis in low-income countries with high tuberculosis incidence: Experiences and perceptions from health care workers in Sub-Saharan Africa and South-East Asia

Impact of decentralisation of childhood TB diagnosis to district hospitals and primary health centers; Example from Uganda

Impact of decentralisation of childhood TB diagnosis to district hospitals and primary health centers; Example from Uganda

Hepatitis C treatment program in Maputo, Mozambique, the challenge of genotypes and key populations: A 5-year retrospective analysis of routine programmatic data

Effect of systematic tuberculosis detection on mortality in young children with severe pneumonia in countries with high incidence of tuberculosis: a stepped-wedge cluster-randomised trial

Novel FujiLAM assay to detect tuberculosis in HIV-positive ambulatory patients in four African countries: a diagnostic accuracy study

Cholera outbreaks in sub-Saharan Africa during 2010-2019: a descriptive analysis

Community-based antiretroviral therapy programs can overcome barriers to retention of patients and decongest health services in sub-Saharan Africa: a systematic review

Diagnostic performance and feasibility of FujiLAM to detect tuberculosis

A digital portable tablet audiometry monitoring tool for patients with drug-resistant tuberculosis