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Snake envenoming: a neglected crisis

Snake envenoming: a neglected crisis

Every year 2 million or more people fall victim to snakebite envenoming, mostly in poor, rural communities of Africa, Asia and Latin America. Between 83,000—138,000 of them die, while hundreds of thousands more suffer debilitating long-term complications or disabilities.


Although some antivenom medicines are highly effective when used promptly and appropriately, many snakebite victims get no treatment at all. Those who do may receive antivenoms which don’t work against the type of snake that bit them, or were not rigorously tested for safety and effectiveness.


To mark World Snakebite Awareness Day on September 19th, the Collection linked below brings together recent MSF work on this highly neglected disease. Several articles and conference presentations help fill evidence gaps on the burden of disease and its impacts or on treatment outcomes with specific antivenoms in specific regions. Others examine how to tackle the formidable challenges of availability and affordability, the absence of regulatory oversight for making, testing and registering antivenoms, and the anemic R&D pipeline for new products—all of which impede access for patients to safe, effective treatment tailored to local snake species.

Mini-Lab—MSF's simplified bacteriology laboratory for low-resource settings

Mini-Lab—MSF's simplified bacteriology laboratory for low-res...
Neglected tropical diseases

Neglected tropical diseases
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Resistance to antibiotics is a growing public health crisis, especially in countries with fragile health systems and in regions at war. One key limitation in most of these settings is a lack of clinical bacteriology laboratory capacity, which leaves medical providers without ways to accurately diagnose patient infections and to tailor antibiotic treatment accordingly. To help fill this critical gap, MSF and partners have developed the Mini-Lab—a small-scale, standalone lab that is easy to transport, set up and operate by staff after only a short training. Its six modules are stocked with everything needed to diagnose common bloodstream and urinary tract infections and to perform antibiotic sensitivity testing using methods adapted to extremely hot climates and remote settings. With Mini-Lab now being rolled out to selected MSF projects, here we highlight the background to its development and some of the research behind the bacteriological tests it incorporates.

Each year hundreds of thousands of people die from a neglected tropical disease, while many more suffer serious illness or lifelong disability. Yet as we mark World Neglected Tropical Diseases (NTD) Day on 30th January, global progress towards eliminating these diseases is threatened by shifting global health priorities and declining investment in the wake of the Covid-19 pandemic.


The content collection linked below offers a snapshot of MSF’s work on managing some of the most deadly NTDs, finding better tools and models of care for highly affected populations, and advocating for greater access to care and increased global funding. Several authors describe our programs and lessons learned from a decade of treating snakebite victims in sub-Saharan Africa. Two studies evaluate shorter, less toxic treatment for visceral leischmaniasis, while a policy analysis proposes critical steps towards eliminating this horrific disease in East Africa. Last, reports from Sokoto, Nigeria describe the collaborative development of a comprehensive model of care for noma.

Journal Article
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Research

Post-surgical scar management and rehabilitation in burn patients: Insights from Gaza’s challenging context - A retrospective descriptive study

Qaradaya AEH, Van Hulse J, Younis J, Swairjo F, Al Far H,  et al.
2026-07-07 • PLOS Global Public Health
2026-07-07 • PLOS Global Public Health

Burn injuries represent a challenge in the Gaza Strip, where access to rehabilitation services is constrained by ongoing conflict and limited healthcare resources. This study describe...

Journal Article
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Case Report/Series

First culture-confirmed melioidosis case in Mozambique: A wakeup call for better diagnostics and clinical awareness

Cruz SC, Raimundo C, Andela L, Marcos J, Joao N,  et al.
2026-05-10 • Oxford Medical Case Reports
2026-05-10 • Oxford Medical Case Reports

Melioidosis is a disease caused by Burkholderia pseudomallei and is an underrecognised cause of severe infection in sub-Saharan Africa. In Mozambique, where infectious diseas...

Journal Article
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Research

Shotgun metagenomic analysis of the oral microbiomes of children with noma

Olaleye M, O’Ferrall AM, Goodman RN, Kabila DW, Peters M,  et al.
2026-03-20 • PLOS Neglected Tropical Diseases
2026-03-20 • PLOS Neglected Tropical Diseases

Noma is a rapidly progressive orofacial gangrene that predominantly affects children living in extreme poverty. Despite its documentation since antiquity and its designation as a Worl...

Journal Article
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Letter

The effects of armed conflict on children and adolescents: Policy statement

Umphrey L, Patel A, Alayyan A, Haq HA, Suchdev PS,  et al.
2026-02-17 • Pediatrics
2026-02-17 • Pediatrics
Journal Article
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Research

Risk stratification of childhood infection using host markers of immune and endothelial activation in Asia (Spot Sepsis): a multi-country, prospective, cohort study

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Van Anh DT,  et al.
2025-09-01 • Lancet Child and Adolescent Health
2025-09-01 • Lancet Child and Adolescent Health

BACKGROUND

Prognostic tools for febrile illnesses are urgently required in resource-constrained community contexts. Circulating immune and endothelial activatio...

Journal Article
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Short Report

Providing emergency medical care at the Belarus-Poland border

Zadykowicz R, Kuc J, Ladomirska J, Zamatto F, Lim SY
2025-05-01 • Forced Migration Review
2025-05-01 • Forced Migration Review