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Noma

Noma

Noma, also known as cancrum oris, is a rapidly progressing life-threatening infection that affects the mouth and face. Noma is preventable and easy to treat if addressed in the early reversible stages, but most often deadly if untreated. The disease most commonly affects children who are chronically malnourished or whose immune systems are otherwise compromised. Noma affects an estimated 140,000 children annually. Noma was added to the WHO's list of Neglected Tropical Diseases in 2023.


MSF is working to discover more about noma. This collection highlights MSF's mixed methods research on treatment outcomes, burden of disease, attitudes towards the disease and other aspects of noma.


For more information on MSF's work on noma, you can also visit https://noma.msf.org/.

Diabetes care in humanitarian settings

Diabetes care in humanitarian settings
Expanding access to lifesaving new TB tools

Expanding access to lifesaving new TB tools
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Diabetes affect hundreds of millions of people worldwide, a large majority of them living in low- and middle-income countries. Yet finding effective strategies, tools and policies for effectively managing this chronic illness—especially amid war, displacement or exclusion from care—is a neglected area of humanitarian medicine. Here we present a cross-section of work on this front by MSF and collaborators. Several studies assess the shift towards community-based, nurse-led models of care in rural settings. Others explore obstacles to diabetes care for war refugees living in camps in Jordan or Lebanon, highlighting how health programs can adapt to their needs. The demonstration that insulin retains potency for 30 days if cooled without refrigeration is opening doors to more patient self-management, as a case study in remote South Sudan shows. At the same time, MSF and others call for regulatory and financing policies that make diabetes medications and supplies cheaper, better adapted to humanitarian settings, and far more available to patients whose lives depend on them.
Many settings with a high burden of drug-resistant tuberculosis (DR-TB) lack access to advanced diagnostics and to groundbreaking new treatments. The Collection linked below spotlights work by MSF and collaborators to analyze barriers, identify gaps, and accelerate the roll-out of these tools to people whose lives hang in the balance. Several reports examine price, regulatory, and patent obstacles that persist despite considerable public investment into developing many of these tools. Other authors examine critical remaining weaknesses in care pathways—especially in screening and diagnosis, and particularly in children. Several studies describe new strategies that could be part of the solution, from a pilot program in Tajikisttan that trains family caregivers to treat children with DR-TB at home, to a person-centered care model adapted to a conflict zone in Afghanistan. Lastly, initial findings demonstrate that pregnant women—another vulnerable population—can be effectively treated for DR- and multidrug-resistant TB, improving maternal outcomes without harming neonates.
Journal Article
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Research

Post-surgical scar management and rehabilitation in burn patients: Insights from Gaza’s challenging context - A retrospective descriptive study

Qaradaya AEH, Van Hulse J, Younis J, Swairjo F, Al Far H,  et al.
2026-07-07 • PLOS Global Public Health
2026-07-07 • PLOS Global Public Health

Burn injuries represent a challenge in the Gaza Strip, where access to rehabilitation services is constrained by ongoing conflict and limited healthcare resources. This study describe...

Journal Article
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Case Report/Series

First culture-confirmed melioidosis case in Mozambique: A wakeup call for better diagnostics and clinical awareness

Cruz SC, Raimundo C, Andela L, Marcos J, Joao N,  et al.
2026-05-10 • Oxford Medical Case Reports
2026-05-10 • Oxford Medical Case Reports

Melioidosis is a disease caused by Burkholderia pseudomallei and is an underrecognised cause of severe infection in sub-Saharan Africa. In Mozambique, where infectious diseas...

Journal Article
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Research

Shotgun metagenomic analysis of the oral microbiomes of children with noma

Olaleye M, O’Ferrall AM, Goodman RN, Kabila DW, Peters M,  et al.
2026-03-20 • PLOS Neglected Tropical Diseases
2026-03-20 • PLOS Neglected Tropical Diseases

Noma is a rapidly progressive orofacial gangrene that predominantly affects children living in extreme poverty. Despite its documentation since antiquity and its designation as a Worl...

Journal Article
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Letter

The effects of armed conflict on children and adolescents: Policy statement

Umphrey L, Patel A, Alayyan A, Haq HA, Suchdev PS,  et al.
2026-02-17 • Pediatrics
2026-02-17 • Pediatrics
Journal Article
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Research

Risk stratification of childhood infection using host markers of immune and endothelial activation in Asia (Spot Sepsis): a multi-country, prospective, cohort study

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Van Anh DT,  et al.
2025-09-01 • Lancet Child and Adolescent Health
2025-09-01 • Lancet Child and Adolescent Health

BACKGROUND

Prognostic tools for febrile illnesses are urgently required in resource-constrained community contexts. Circulating immune and endothelial activatio...

Journal Article
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Short Report

Providing emergency medical care at the Belarus-Poland border

Zadykowicz R, Kuc J, Ladomirska J, Zamatto F, Lim SY
2025-05-01 • Forced Migration Review
2025-05-01 • Forced Migration Review