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World Malaria Day 2023 | Collections | MSF Science Portal
World Malaria Day 2023

World Malaria Day 2023

World Malaria Day is April 25th. The theme for 2023 is "Zero malaria: invest, innovate, implement" and the importance of reaching marginalized populations with the tools and strategies that are currently available.

This collection highlights research on this theme, especially the latter two "i's": From research on Seasonal Chemoprophylaxis (SMC) and mass drug administration (MDA), to analyzing the reach of gene mutations (HRP2) in new environments, to other interventional research topics, these articles show how innovative approaches can be successfully implemented even in the most challenging settings to fight this global public health threat.

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MSF Paediatric Days 2024 abstracts
MSF Paediatric Days 2024 abstracts
On 3-4 May in Nairobi, Kenya, MSF gathered staff from our projects with experts from academia, clinical practice and the non-governmental sector to consider key issues in humanitarian paediatrics. These included: Vaccination and vaccine-preventable diseases: Amid post-Covid-19 global setbacks in child vaccination coverage, sessions spotlighted recent increases in vaccine-preventable disease outbreaks, potential new vaccination strategies and emergency responses, and MSF’s role in vaccine advocacy and catch-up campaigns. Nutrition: Talks covered the nexus of nutrition with other key conference topics, the latest malnutrition guidance and tools, and MSF’s priorities in nutritional care. Paediatric HIV: With half of all HIV-positive children globally not receiving antiretroviral therapy, presenters reviewed the latest paediatric testing/treatment recommendations and discussed barriers and potential solutions to implementation, nutritional challenges in children with HIV, and systems strengthening for preventing and monitoring paediatric HIV. Click below to read the abstracts. And stay tuned for more conference content, coming soon.
Noma
Noma
Mini-Lab—MSF's simplified bacteriology laboratory for low-resource settings
Mini-Lab—MSF's simplified bacteriology laboratory for low-res...
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Noma, also known as cancrum oris, is a rapidly progressing life-threatening infection that affects the mouth and face. Noma is preventable and easy to treat if addressed in the early reversible stages, but most often deadly if untreated. The disease most commonly affects children who are chronically malnourished or whose immune systems are otherwise compromised. Noma affects an estimated 140,000 children annually. Noma was added to the WHO's list of Neglected Tropical Diseases in 2023.

MSF is working to discover more about noma. This collection highlights MSF's mixed methods research on treatment outcomes, burden of disease, attitudes towards the disease and other aspects of noma.

For more information on MSF's work on noma, you can also visit https://noma.msf.org/.

Resistance to antibiotics is a growing public health crisis, especially in countries with fragile health systems and in regions at war. One key limitation in most of these settings is a lack of clinical bacteriology laboratory capacity, which leaves medical providers without ways to accurately diagnose patient infections and to tailor antibiotic treatment accordingly. To help fill this critical gap, MSF and partners have developed the Mini-Lab—a small-scale, standalone lab that is easy to transport, set up and operate by staff after only a short training. Its six modules are stocked with everything needed to diagnose common bloodstream and urinary tract infections and to perform antibiotic sensitivity testing using methods adapted to extremely hot climates and remote settings. With Mini-Lab now being rolled out to selected MSF projects, here we highlight the background to its development and some of the research behind the bacteriological tests it incorporates.
Journal Article
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Commentary

Moving towards malaria elimination with safer treatment for children with G6PD deficiency

Boum Y II, Moukoko CEE, Parikh S
2023-04-01 • Lancet Infectious Diseases
2023-04-01 • Lancet Infectious Diseases
Journal Article
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Research

Effect of large-scale mass drug administration for malaria on mortality and morbidity in Angumu health zone, Ituri, Democratic Republic of Congo

Grout L, Katuala Givo Y, Newport T, Mahamat TA, Gitahi P,  et al.
2023-02-06 • Malaria Journal
2023-02-06 • Malaria Journal
BACKGROUND
Angumu health zone in Ituri, Democratic Republic of Congo, is a highly malaria-endemic area with an overburdened health system and hosting internally displaced persons (ID...
Journal Article
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Short Report

Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan

Molina-de la Fuente I, Benito MJS, Flevaud L, Ousley J, Pasquale HA,  et al.
2023-01-01 • Emerging Infectious Diseases
2023-01-01 • Emerging Infectious Diseases
Pfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for ...
Journal Article
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Research

Long-lasting insecticidal nets provide protection against malaria for only a single year in Burundi, an African highland setting with marked malaria seasonality

Van Bortel W, Mariën J, Jacobs BKM, Sinzinkayo D, Sinarinzi P,  et al.
2022-12-01 • BMJ Global Health
2022-12-01 • BMJ Global Health
BACKGROUND
Long-lasting insecticidal nets (LLINs) are one of the key interventions in the global fight against malaria. Since 2014, mass distribution campaigns of LLINs aim for unive...
Conference Material
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Video

Implementation quality of seasonal malaria chemoprevention: a qualitative study exploring the perspectives of caregivers and community distributors in Burkina Faso and Chad

Lasmi K
2022-11-29 • MSF Paediatric Days 2022
2022-11-29 • MSF Paediatric Days 2022
Journal Article
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Research

Evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria and prevalence of pfhrp2/3 deletions in Aweil, South Sudan

Lynch E, Jensen TO, Assao B, Chihana ML, Turuho T,  et al.
2022-09-09 • Malaria Journal
2022-09-09 • Malaria Journal
BACKGROUND
Rapid diagnostic tests (RDT) for malaria are the primary tool for malaria diagnosis in sub-Saharan Africa but the utility of the most commonly used histidine-rich protein ...
Conference Material
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Video

Mass drug administration as a tool for rapid reduction of malaria morbidity and mortality in emergency settings

Grout L
2022-06-21 • Epicentre Scientific Day Paris 2022
2022-06-21 • Epicentre Scientific Day Paris 2022
Conference Material
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Video

Understanding and improving case management of severe febrile illness in highly malaria-endemic settings an observational implementation study in the Democratic Republic of the Congo, Nigeria and Uganda

Signorell A
2022-06-07 • MSF Scientific Days International 2022
2022-06-07 • MSF Scientific Days International 2022
Journal Article
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Research

Prevalence of malaria in an area receiving seasonal malaria chemoprevention in Niger

Coldiron ME, Assao B, Guindo O, Sayinzoga-Makombe N, Koskalova A,  et al.
2021-10-24 • Malaria Journal
2021-10-24 • Malaria Journal
BACKGROUND
Malaria transmission is highly seasonal in Niger. Despite the introduction of seasonal malaria chemoprevention (SMC) in the Magaria District, malaria incidence remains hig...
Journal Article
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Research

Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger

Coldiron ME, Assao B, Langendorf C, Sayinzoga-Makombe N, Ciglenecki I,  et al.
2019-12-26 • Malaria Journal
2019-12-26 • Malaria Journal
BACKGROUND
Rapid diagnostic tests (RDT) for malaria are common, but their performance varies. Tests using histidine-rich protein 2 (HRP2) antigen are most common, and many have high ...
Journal Article
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Research

Are village health volunteers as good as basic health staffs in providing malaria care? A country wide analysis from Myanmar, 2015

Linn NYY, Kathirvel S, Das M, Thapa B, Rahman MM,  et al.
2018-06-20 • Malaria Journal
2018-06-20 • Malaria Journal
BACKGROUND
Malaria is one of the major public health problems in Myanmar. Village health volunteers (VHV) are the key malaria diagnosis and treatment service provider at community le...
Journal Article
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Research

Prevalence and diagnostics of congenital malaria in rural Burundi, a cross-sectional study

Stassijns J, van den Boogaard W, Pannus P, Nkunzimana A, Rosanas-Urgell A
2016-08-30 • Malaria Journal
2016-08-30 • Malaria Journal
BACKGROUND
Congenital malaria, defined as the presence of asexual forms of malaria parasites in the peripheral blood during the first 7 days of life, remains a neglected area of rese...
Journal Article
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Research

Global plagues and the Global Fund: Challenges in the fight against HIV, TB and malaria

Ioana Chiotan D, Upshur R, Ford NP
2003-04-01 • BMC International Health and Human Rights
2003-04-01 • BMC International Health and Human Rights
BACKGROUND
Although a grossly disproportionate burden of disease from HIV/AIDS, TB and malaria remains in the Global South, these infectious diseases have finally risen to the top of...