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Journal Article
|Research

Lessons and challenges for measles control from unexpected large outbreak, Malawi

Minetti A, Kagoli M, Katsulukuta A, Huerga H, Featherstone A, Chiotcha H, Noel D, Bopp C, Sury L, Fricke R, Iscla M, Hurtado N, Ducomble T, Nicholas S, Kabuluzi S, Grais RF, Luquero FJ
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Lessons and challenges for measles control from unexpected large outbreak, Malawi | Journal Article / Research | MSF Science Portal
Abstract
Despite high reported coverage for routine and supplementary immunization, in 2010 in Malawi, a large measles outbreak occurred that comprised 134,000 cases and 304 deaths. Although the highest attack rates were for young children (2.3%, 7.6%, and 4.5% for children <6, 6-8, and 9-11 months, respectively), persons >15 years of age were highly affected (1.0% and 0.4% for persons 15-19 and >19 years, respectively; 28% of all cases). A survey in 8 districts showed routine coverage of 95.0% for children 12-23 months; 57.9% for children 9-11 months; and 60.7% for children covered during the last supplementary immunization activities in 2008. Vaccine effectiveness was 83.9% for 1 dose and 90.5% for 2 doses. A continuous accumulation of susceptible persons during the past decade probably accounts for this outbreak. Countries en route to measles elimination, such as Malawi, should improve outbreak preparedness. Timeliness and the population chosen are crucial elements for reactive campaigns.

Countries

Malawi

Subject Area

measlesoutbreaks

Languages

English
DOI
10.3201/eid1902.120301
Published Date
01 Feb 2013
PubMed ID
23343504
Journal
Emerging Infectious Diseases
Volume | Issue | Pages
Volume 19, Issue 2
Issue Date
2013-02-01
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