Abstract
SUMMARY BOX
-- There has been open and closed vial COVID-19 vaccine wastage in low-income, middle-income and high-income countries, with wastage rates of up to 30%.
-- Plans to monitor, forecast and ultimately reduce vaccine wastage are urgently needed in every country.
-- Open vial wastage should be reduced by strategies increasing overall vaccination rates, such as overbooking appointments and appointment-free vaccination, as well as through technologies maximising the number of doses being extracted from the vial.
-- Closed vial wastage should be reduced by timely, well-organised surplus donations and reallocations, as well as supporting effective supply chain management in recipient countries.