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Journal Article > Research

Long-term Clinical Outcomes in Visceral Leishmaniasis-HIV Co-infected Patients during and after Pentamidine Secondary Prophylaxis in Ethiopia: a single-arm clinical trial

Diro EGJ, Ritmeijer KKD, Boelaert M, Alves F, Mohammed R, Abongomera C, Ravinetto R, De Crop M, Fikre H, Adera C, van Loen H, Tsoumanis A, Adriaensen W, Hailu ADE, van Griensven J
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Abstract
We have conducted a single-arm trial evaluating monthly pentamidine secondary prophylaxis (PSP) to prevent visceral leishmaniasis (VL) relapse in Ethiopian HIV-patients. Outcomes at 12 months of PSP have been previously reported, supporting PSP effectiveness and safety. However, remaining relapse-free after PSP discontinuation is vital. We now report outcomes and associated factors for a period of upto 2.5 years after initiating PSP, including one year follow-up after PSP discontinuation.
Countries
Ethiopia
Subject Area
neglected tropical diseasesHIV/AIDS
DOI
10.1093/cid/cix807
Published Date
13-Sep-2017
PubMed ID
29020217
Languages
English
Journal
Clinical Infectious Diseases
Volume / Issue / Pages
Volume 66, Issue 3
Issue Date
13-Sep-2017
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