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v2.1.5153.produswest2
Journal Article
|Research

Single-dose oral ciprofloxacin prophylaxis as a response to a meningococcal meningitis epidemic in the African meningitis belt: A 3-arm, open-label, cluster-randomized trial

Coldiron ME, Assao B, Page AL, Hitchings MD, Alcoba G, Ciglenecki I, Langendorf C, Mambula C, Adehossi E, Sidikou F, Tassiou EI, De Lastours V, Grais RF
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Abstract
Antibiotic prophylaxis for contacts of meningitis cases is not recommended during outbreaks in the African meningitis belt. We assessed the effectiveness of single-dose oral ciprofloxacin administered to household contacts and in village-wide distributions on the overall attack rate (AR) in an outbreak of meningococcal meningitis.

Countries

Niger

Subject Area

meningitis

Languages

English
DOI
10.1371/journal.pmed.1002593
Published Date
26 Jun 2018
PubMed ID
29944651
Journal
PLOS Medicine
Volume | Issue | Pages
Volume 15, Issue 6
Issue Date
2018-06-26
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Single-dose oral ciprofloxacin prophylaxis as a response to a meningococcal meningitis epidemic in the African meningitis belt: A 3-arm, open-label, cluster-randomized trial | Journal Article / Research | MSF Science Portal