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Journal Article > Research

Pooled HIV-1 Viral Load Testing Using Dried Blood Spots to Reduce the Cost of Monitoring Antiretroviral Treatment in a Resource-Limited Setting

Pannus P, Fajardo E, Metcalf CJ, Coulborn R M, Duran LT, Bygrave H, Ellman T, Garone DB, Murowa MM, Mwenda R, Reid AJ, Preiser W
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Abstract
: Rollout of routine HIV-1 viral load monitoring is hampered by high costs and logistical difficulties associated with sample collection and transport. New strategies are needed to overcome these constraints. Dried blood spots from finger pricks have been shown to be more practical than the use of plasma specimens, and pooling strategies using plasma specimens have been demonstrated to be an efficient method to reduce costs. This study found that combination of finger-prick dried blood spots and a pooling strategy is a feasible and efficient option to reduce costs, while maintaining accuracy in the context of a district hospital in Malawi.
Countries
Malawi
Subject Area
HIV/AIDS
DOI
10.1097/QAI.0b013e3182a61e63
Published Date
25-Jul-2013
PubMed ID
23892241
Languages
English
Journal
Journal of Acquired Immune Deficiency Syndromes (1999)
Volume / Issue / Pages
Volume 64, Issue 2
Issue Date
01-Oct-2013
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