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Journal Article
|Review

Eye Examination for Early Diagnosis of Disseminated Tuberculosis in Patients with AIDS

Heiden D, Saranchuk P, Keenan JD, Ford NP, Lowinger A, Yen M, McCune JM, Rao NA
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Abstract
Choroidal tuberculosis is present in 5-20% of patients with disseminated tuberculosis, and point-of-care dilated binocular indirect ophthalmoscopy eye examination can provide immediate diagnosis. In geographical areas of high tuberculosis prevalence and in susceptible patients (CD4 counts less than 200 cells per μL) detection of choroidal granulomas should be accepted as evidence of disseminated tuberculosis. With training and proper support, eye screening can be done by HIV/AIDS clinicians, allowing early tuberculosis treatment. In regions with a high burden of tuberculosis, we recommend that eye screening be a standard part of the initial assessment of susceptible patients, including at a minimum all patients with HIV/AIDS with CD4 less than 100 cells per μL with or without eye symptoms, and with or without suspicion of disseminated tuberculosis.

Subject Area

tuberculosisHIV/AIDS

Languages

English
DOI
10.1016/S1473-3099(15)00269-8
Published Date
18 Feb 2016
PubMed ID
26907735
Journal
Lancet Infectious Diseases
Volume | Issue | Pages
Volume 16, Issue 4
Issue Date
2016-04-01
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Eye Examination for Early Diagnosis of Disseminated Tuberculosis in Patients with AIDS | Journal Article / Review | MSF Science Portal