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Expanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds | Journal Article / Research | MSF Science Portal
Journal Article
|Research

Expanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds

Bonner K, Siemieniuk R, Boozary A, Roberts TR, Fajardo E, Cohn J
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Abstract
HIV viral load (VL) testing is the gold standard for antiretroviral treatment monitoring, but many barriers exist to VL testing in resource-limited settings, including storage and transport limitations for whole blood and plasma. Data from various studies indicate that HIV RNA is stable beyond current recommendations. We conducted a systematic review to assess stability data of HIV RNA in whole blood and plasma across times and temperatures.

Countries

none

Subject Area

HIV/AIDS

Languages

English
DOI
10.1371/journal.pone.0113813
Published Date
01 Dec 2014
PubMed ID
25437009
Journal
PLOS One
Volume | Issue | Pages
Volume 9, Issue 12
Issue Date
2014-12-01
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