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Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 9 of 9 Items
Showing 1 - 9 of 9 Items
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Journal Article
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Research

Improved vaccination coverage after two rounds of multi-antigenic catch-up vaccination in Mauritania

Pagola-Ugarte M, Rakesh A, Gil-Cuesta J, Kidinda D, Kelly TM,  et al.
2024-02-14 • PLOS Global Public Health
2024-02-14 • PLOS Global Public Health
Although Mauritania carried out its Expanded Programme on Immunization (EPI), in 2015 the goal of vaccination coverage (VC) remained unmet in Bassikounou district and Mbera camp, context...
Journal Article
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Research

Impact and cost-effectiveness of rotavirus vaccination in Niger: a modelling study evaluating alternative rotavirus vaccines

Debellut F, Tang K, Clark A, Pecenka C, Assao B,  et al.
2022-10-05 • BMJ Open
2022-10-05 • BMJ Open
OBJECTIVES
To evaluate the cost-effectiveness of alternative rotavirus vaccines in Niger, using UNIVAC, a proportionate outcomes model.

SETTING
The study leverages globa...
Journal Article
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Research

Immunogenicity of an oral rotavirus vaccine administered with prenatal nutritional support in Niger: A cluster randomized clinical trial

Isanaka S, Garba S, Plikaytis BD, McNeal MM, Guindo O,  et al.
2021-08-10 • PLOS Medicine
2021-08-10 • PLOS Medicine
BACKGROUND
Nutritional status may play a role in infant immune development. To identify potential boosters of immunogenicity in low-income countries where oral vaccine efficacy is lo...
Journal Article
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Review

Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis

Sanchez-Padilla E, Guerin PJ, Steele AD, Luquero FJ
2009-09-01 • Lancet Infectious Diseases
2009-09-01 • Lancet Infectious Diseases
Two new rotavirus vaccines have recently been licensed in many countries. However, their efficacy has only been shown against certain serotypes commonly circulating in Europe, North Amer...
Journal Article
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Research

A mixture model to assess the the immunogenicity of an oral rotavirus vaccine among healthy infants in Niger

Hitchings MD, Cummings DAT, Grais RF, Isanaka S
2020-12-03 • Vaccine
2020-12-03 • Vaccine
Analysis of immunogenicity data is a critical component of vaccine development, providing a biological basis to support any observed protection from vaccination. Conventional methods for...
Journal Article
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Research

Efficacy of a low-cost, heat-stable oral rotavirus vaccine in Niger

Isanaka S, Guindo O, Langendorf C, Matar Seck A, Plikaytis BD,  et al.
2017-03-23 • New England Journal of Medicine
2017-03-23 • New England Journal of Medicine
BACKGROUND
Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate eff...
Journal Article
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Research

Rotavirus vaccine efficacy up to 2 years of age and against diverse circulating rotavirus strains in Niger: Extended follow-up of a randomized controlled trial

Isanaka S, Langendorf C, McNeal MM, Meyer N, Plikaytis BD,  et al.
2021-07-02 • PLOS Medicine
2021-07-02 • PLOS Medicine
BACKGROUND
Rotavirus vaccination is recommended in all countries to reduce the burden of diarrhea-related morbidity and mortality in children. In resource-limited settings, rotavirus...
Journal Article
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Pre-Print

The burden of vaccine hesitancy for routine immunization in Yaounde-Cameroon: restrictive sampling technique

Yakum MN, Funwie AD, Ajong AB, Tsafack M, Ebaze LE,  et al.
2022-02-21 • medRxiv
2022-02-21 • medRxiv
Immunization is the most cost-effective health intervention in the world yet, vaccination uptake is still low with less than 50% of children aged 12-23 months fully vaccinated Cameroon. ...
Journal Article
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Research

Etiology and incidence of moderate-to-severe diarrhea in young children in Niger

Platts-Mills JA, Houpt ER, Liu J, Zhang J, Guindo O,  et al.
2021-12-31 • Journal of the Pediatric Infectious Diseases Society
2021-12-31 • Journal of the Pediatric Infectious Diseases Society
BACKGROUND
High-resolution data on the etiology of childhood diarrhea in countries with the highest burden and mortality remain sparse and are needed to inform burden estimates and p...