Santos ALS, Rodrigues IA, d’Avila-Levy CM, Sodré CL, Ritmeijer KKD, et al.
2023-10-19 • Pathogens
2023-10-19 • Pathogens
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (als...
Gobbi F, Angheben A, Anselmi M, Postiglione C, Repetto EC, et al.
2014-12-11 • PLOS Neglected Tropical Diseases
2014-12-11 • PLOS Neglected Tropical Diseases
BACKGROUND Chagas disease (CD) is endemic in Central and South America, Mexico and even in some areas of the United States. However, cases have been increasingly recorded also in no...
Villa L, Morote S, Bernal O, Bulla D, Albajar Viñas P
2007-10-30 • Memorias do Instituto Oswaldo Cruz
2007-10-30 • Memorias do Instituto Oswaldo Cruz
In this article, Médicos Sin Fronteras (MSF) Spain faces the challenge of selecting, piecing together, and conveying in the clearest possible way, the main lessons learnt over the course...
Yun O, Lima MA, Ellman T, Chambi W, Castillo S, et al.
2009-07-07 • PLOS Neglected Tropical Diseases
2009-07-07 • PLOS Neglected Tropical Diseases
BACKGROUND: Chagas disease (American trypanosomiasis) is a zoonotic or anthropozoonotic disease caused by the parasite Trypanosoma cruzi. Predominantly affecting populations in poor...
Parrado R, Ramirez JC, de la Barra A, Alonso-Vega C, Juiz N, et al.
2018-12-03 • Antimicrobial Agents and Chemotherapy
2018-12-03 • Antimicrobial Agents and Chemotherapy
This work evaluated a serial blood sampling procedure to enhance the sensitivity of duplex real-time PCR (qPCR) for baseline detection and quantification of parasitic loads and post-trea...
Brum-Soares L, Cubides JC, Burgos I, Monroy C, Castillo L, et al.
2016-12-01 • Revista da Sociedade Brasileira de Medicina Tropical
2016-12-01 • Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION Geographical, epidemiological, and environmental differences associated with therapeutic response to Chagas etiological treatment have been previously discussed. This st...
2007-06-01 • Revista da Sociedade Brasileira de Medicina Tropical
2007-06-01 • Revista da Sociedade Brasileira de Medicina Tropical
Trypanosoma cruzi infection is often not detected early on or actively diagnosed, partly because most infected individuals are either asymptomatic or oligosymptomatic. Moreover, in most ...
Pane S, Giancola ML, Piselli P, Corpolongo A, Repetto EC, et al.
2018-05-08 • BMC Infectious Diseases
2018-05-08 • BMC Infectious Diseases
Chagas disease (CD) is a systemic parasitic infection caused by the protozoan Trypanosoma cruzi, whose chronic phase may lead to cardiac and intestinal disorders. Endemic in Latin Americ...
Repetto EC, Zachariah R, Kumar AMV, Angheben A, Gobbi F, et al.
2015-09-25 • PLOS Neglected Tropical Diseases
2015-09-25 • PLOS Neglected Tropical Diseases
OBJECTIVES Chagas disease (CD) represents a growing problem in Europe; Italy is one of the most affected countries but there is no national framework for CD and access-to-care is cha...
Antinori S, Galimberti L, Grande R, Bianco R, Oreni L, et al.
2018-03-16 • Clinical Microbiology and Infection
2018-03-16 • Clinical Microbiology and Infection
OBJECTIVES:
We aimed to assess the prevalence and risk factors for Chagas disease (CD) in Latin American immigrants and to evaluate the accuracy of diagnostic tests. Moreover, we of...
Ramirez JC, Parrado R, Sulleiro E, de la Barra A, Rodriguez M, et al.
2017-11-27 • PLOS One
2017-11-27 • PLOS One
Real-Time PCR (qPCR) testing is recommended as both a diagnostic and outcome measurement of etiological treatment in clinical practice and clinical trials of Chagas disease (CD), but no ...
Chagas disease (American trypanosomiasis) is endemic in 21 countries of the Americas, where control is largely focused on elimination of the domestic insect vectors (Triatominae) coupled...
2017-06-01 • Revista da Sociedade Brasileira de Medicina Tropical
2017-06-01 • Revista da Sociedade Brasileira de Medicina Tropical
After more than one century since its discovery, Chagas disease is still extremely prevalent in 21 Latin American countries. Chagas disease is one of the most concerning public health pr...
Escriba JM, Ponce E, Romero Ade D, Albajar Viñas P, Marchiol A, et al.
2009-11-01 • Memorias do Instituto Oswaldo Cruz
2009-11-01 • Memorias do Instituto Oswaldo Cruz
Between 1999-2002, Médécins Sans Frontières-Spain implemented a project seeking to determine the efficacy and safety of benznidazole in the treatment of recent chronic Chagas disease in ...
Forsyth C, Meymandi S, Moss I, Cone J, Cohen RM, et al.
2019-09-26 • PLOS Neglected Tropical Diseases
2019-09-26 • PLOS Neglected Tropical Diseases
BACKGROUND Chagas disease (CD) affects over 300,000 people in the United States, but fewer than 1% have been diagnosed and less than 0.3% have received etiological treatment. This is...
Sperandio da Silva G, Felix Mediano M, Hasslocher-Moreno A, Holanda M, Silvestre de Sousa A, et al.
2017-06-22 • Journal of Antimicrobial Chemotherapy
2017-06-22 • Journal of Antimicrobial Chemotherapy
BACKGROUND Up to half of patients with Chagas' disease under benznidazole treatment present adverse drug reactions (ADRs) and up to one-third do not complete standard treatment. ...
