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Showing 1 - 20 of 83 Items
Showing 1 - 20 of 83 Items
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Journal Article
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Review

Cutaneous leishmaniasis in Afghanistan

Rahimi BA, Ghatee MA, Habib MN, Farooqi K, Ritmeijer K,  et al.
2025-05-07 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2025-05-07 • Transactions of the Royal Society of Tropical Medicine and Hygiene

Old World cutaneous leishmaniasis (OWCL) is a sand fly-transmitted skin infection caused by Leishmania species that extends from West Africa to China. Afghanistan probably has the hig...

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Letter

Reply to: What about health system strengthening and internal brain drain? [letter]

Zachariah R, Ford NP, Philips M, Draguez B, Harries AD
2009-05-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2009-05-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
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Blood transfusion in the care of patients with visceral leishmaniasis: a review of practices in therapeutic efficacy studies

Dahal P, Singh-Phulgenda S, Wilson JM, Cota G, Ritmeijer K,  et al.
2024-05-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2024-05-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Blood transfusion remains an important aspect of patient management in visceral leishmaniasis (VL). However, transfusion triggers considered are poorly understood. This review summarises...

High prevalence of lipoatrophy among patients on stavudine-containing first-line antiretroviral therapy regimens in Rwanda

van Griensven J, De Naeyer L, Mushi T, Ubarijoro S, Gashumba D,  et al.
2007-08-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2007-08-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This study was conducted among individuals placed on WHO-recommended first-line antiretroviral therapy (ART) at two urban health centres in Kigali, Rwanda, in order to determine (a) the ...

TB treatment in a chronic complex emergency: treatment outcomes and experiences in Somalia

Liddle KF, Elema R, Thi SS, Venis S
2013-09-29 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2013-09-29 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Médecins Sans Frontières (MSF) provides TB treatment in Galkayo and Marere in Somalia. MSF international supervisory staff withdrew in 2008 owing to insecurity but maintained daily commu...

Baseline characteristics, response to and outcome of antiretroviral therapy among patients with HIV-1, HIV-2 and dual infection in Burkina Faso

Harries K, Zachariah R, Manzi M, Firmenich P, Mathela R,  et al.
2009-09-23 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2009-09-23 • Transactions of the Royal Society of Tropical Medicine and Hygiene
In an urban district hospital in Burkina Faso we investigated the relative proportions of HIV-1, HIV-2 and HIV-1/2 among those tested, the baseline sociodemographic and clinical characte...

Targeting CD4 testing to a clinical subgroup of patients could limit unnecessary CD4 measurements, premature antiretroviral treatment and costs in Thyolo District, Malawi

Zachariah R, Teck R, Ascurra O, Humblet P, Harries AD
2006-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2006-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Malawi offers antiretroviral treatment (ART) to all HIV-positive adults who are clinically classified as being in WHO clinical stage III or IV without 'universal' CD4 testing. This study...

Field research in humanitarian medical programmes. Treatment of a cohort of tuberculosis patients using the Manyatta regimen in a conflict zone in South Sudan

Keus K, Houston S, Melaku Y, Burling S
2008-01-31 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-01-31 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This is a descriptive report of a pilot project of tuberculosis (TB) treatment in a conflict zone. A TB programme was implemented by Médecins Sans Frontières(MSF)-Holland in a semi-nomad...

Effectiveness of melarsoprol and eflornithine as first-line regimens for gambiense sleeping sickness in nine Médecins Sans Frontières programmes

Balasegaram M, Young H, Chappuis F, Priotto G, Raguenaud ME,  et al.
2008-10-21 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-10-21 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This paper describes the effectiveness of first-line regimens for stage 2 human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense infection in nine Médecins Sans Frontièr...

Descriptive spatial analysis of the cholera epidemic 2008-2009 in Harare, Zimbabwe: a secondary data analysis

Luque Fernandez MA, Mason PR, Gray H, Bauernfeind A, Maes P
2010-11-13 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2010-11-13 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This ecological study describes the cholera epidemic in Harare during 2008-2009 and identifies patterns that may explain transmission. Rates ratios of cholera cases by suburb were calcul...

Weight loss after the first year of stavudine-containing antiretroviral therapy and its association with lipoatrophy, virological failure, adherence and CD4 counts at primary health care level in Kigali, Rwanda

van Griensven J, Zachariah R, Mugabo J, Reid AJ
2010-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2010-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This study was conducted among 609 adults on stavudine-based antiretroviral treatment (ART) for at least one year at health center level in Kigali, Rwanda to (a) determine the proportion...

Use of Lot Quality Assurance Sampling (LQAS) to estimate vaccination coverage helps guide future vaccination efforts

Alberti KP, Guthmann JP, Fermon F, Nargaye KD, Grais RF
2008-03-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-03-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Inadequate evaluation of vaccine coverage after mass vaccination campaigns, such as used in national measles control programmes, can lead to inappropriate public health responses. Overes...

How has the Zimbabwe mycobacterial culture and drug sensitivity testing system among re-treatment tuberculosis patients functioned during the scale-up of the Xpert MTB/RIF assay?

Timire C, Takarinda KC, Harries AD, Mutunzi H, Manyame-Murwira B,  et al.
2018-06-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2018-06-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
In Zimbabwe, while the Xpert MTB/RIF assay is being used for diagnosing tuberculosis and rifampicin-resistance, re-treatment tuberculosis (TB) patients are still expected to have culture...

Unresponsiveness to AmBisome in some Sudanese patients with kala-azar

Mueller M, Ritmeijer KKD, Balasegaram M, Koummuki Y, Santana MR,  et al.
2007-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2007-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
In Sudan, two treatments are currently registered for visceral leishmaniasis: sodium stibogluconate (SSG) as first line and liposomal amphotericin B (AmBisome) as second line. We present...

Task shifting in HIV/AIDS: opportunities, challenges and proposed actions for sub-Saharan Africa

Zachariah R, Ford NP, Philips M, Lynch S, Massaquoi M,  et al.
2009-06-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2009-06-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Sub-Saharan Africa is facing a crisis in human health resources due to a critical shortage of health workers. The shortage is compounded by a high burden of infectious diseases; emigrati...

Loss to follow up from isoniazid preventive therapy among adults attending HIV voluntary counseling and testing sites in Uganda

Namuwenge P, Mukonzo JK, Kiwanuka N, Wayenze R, Byaruganga R,  et al.
2012-02-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2012-02-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Among HIV-infected adults attending non-governmental organization voluntary counseling and testing (VCT) sites in Uganda that provide a nine-month course of isoniazid preventive treatmen...

Behavioural characteristics, prevalence of Chlamydia trachomatis and antibiotic susceptibility of Neisseria gonorrhoeae in men with urethral discharge in Thyolo, Malawi

Zachariah R, Harries AD, Nkhoma W, Arendt V, Nchingula D,  et al.
2008-01-25 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-01-25 • Transactions of the Royal Society of Tropical Medicine and Hygiene
A study was carried out in 2000/2001 in a rural district of Malawi among men presenting with urethral discharge, in order to (a) describe their health-seeking and sexual behaviour, (b) d...

Chloroquine, sulfadoxine-pyrimethamine and amodiaquine efficacy for the treatment of uncomplicated Plasmodium falciparum malaria in Upper Nile, south Sudan

van den Broek IVF, Gatkoi T, Lowoko B, Nzila A, Ochong E,  et al.
2008-01-31 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-01-31 • Transactions of the Royal Society of Tropical Medicine and Hygiene
The current first-line and second-line drugs for Plasmodium falciparum malaria in South Sudan, chloroquine and sulfadoxine-pyrimethamine (SP), were evaluated and compared with amodiaquin...

A neglected disease of humans: a new focus of visceral leishmaniasis in Bakool, Somalia

Marlet MVL, Wuillaume F, Jacquet D, Quispe KW, Dujardin JC,  et al.
2008-02-07 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-02-07 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Visceral leishmaniasis (VL) was observed in children in Bakool region, Somalia, an area where VL has not been reported before. We describe the extent of the problem in this war- and fami...

Persistent 'hotspots' of lymphatic filariasis microfilaraemia despite 14 years of mass drug administration in Ghana

Biritwum NK, Yikpotey P, Marfo BK, Odoom S, Mensah EO,  et al.
2016-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2016-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
BACKGROUND
Among the 216 districts in Ghana, 98 were declared endemic for lymphatic filariasis in 1999 after mapping. Pursuing the goal of elimination, WHO recommends annual treatmen...