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Showing 1 - 20 of 20 Items
Showing 1 - 20 of 20 Items
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Predictive risk assessment and targeted testing could enhance STI diagnosis in a high HIV prevalence setting in Eswatini

Kerschberger B, Lekelem S, Ntshalintshali N, Mukooza E, Daka M,  et al.
2025-09-29 • Scientific Reports
2025-09-29 • Scientific Reports

Sexually transmitted infections (STIs) present significant public health challenges in resource-limited set...

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Enhancing tuberculosis (TB) case detection among hospitalized patients through lay health worker led screening: a before-and-after study in KwaZulu-Natal, South Africa

Bulti AB, Dumicho AY, Shigayeva A, Van Cutsem G, Steele SJ,  et al.
2025-04-23 • Scientific Reports
2025-04-23 • Scientific Reports

Tuberculosis (TB) among hospitalized patients is underdiagnosed. This study assessed systematic TB-screenin...

A Pan Plasmodium lateral flow recombinase polymerase amplification assay for monitoring malaria parasites in vectors and human populations

Higgins M, Kristan M, Collins EL, Messenger LA, Dombrowski JG,  et al.
2024-08-30 • Scientific Reports
2024-08-30 • Scientific Reports

Robust diagnostic tools and surveillance are crucial for malaria control and elimination efforts. Malaria c...

Supporting re-engagement with HIV services after treatment interruption in South Africa: a mixed method program evaluation of MSF’s Welcome Service

Arendse KD, Walker C, Pfaff C, Lebelo K, Cassidy T,  et al.
2024-03-27 • Scientific Reports
2024-03-27 • Scientific Reports
Psychosocial challenges impact patients’ ability to remain on antiretroviral therapy lifelong, magnified by disorganized health-systems and healthcare worker (HCW) attitudes. To address ...

Enhancing tuberculosis (TB) diagnosis among hospitalized patients in KwaZulu-Natal, South Africa: a before-and-after study of a lay health worker-driven intervention

Bulti AB, Dumicho AY, Shigayeva A, van Cutsem G, Steele SJ,  et al.
2024-03-08 • Scientific Reports
2024-03-08 • Scientific Reports

BACKGROUND 

Tuberculosis (TB) among hospitalized patients is underdiagnosed. This study assessed systematic TB-screen...

Genomic surveillance of SARS-CoV-2 reveals highest severity and mortality of delta over other variants: evidence from Cameroon

Fokam J, Essomba RG, Njouom R, Okomo MCA, Eyangoh S,  et al.
2023-12-08 • Scientific Reports
2023-12-08 • Scientific Reports
While the SARS-CoV-2 dynamic has been described globally, there is a lack of data from Sub-Saharan Africa. We herein report the dynamics of SARS-CoV-2 lineages from March 2020 to March 2...

Detection of insecticide resistance markers in Anopheles funestus from the Democratic Republic of the Congo using a targeted amplicon sequencing panel

Acford-Palmer H, Campos M, Bandibabone JB, N’Do S, Bantuzeko C,  et al.
2023-10-13 • Scientific Reports
2023-10-13 • Scientific Reports
Vector control strategies have been successful in reducing the number of malaria cases and deaths globally, but the spread of insecticide resistance represents a significant threat to di...

Fetal sex and risk of pregnancy-associated malaria in Plasmodium falciparum-endemic regions: a meta-analysis

Unger HW, Hadiprodjo AJ, Gutman JR, Briand V, Fievet N,  et al.
2023-06-26 • Scientific Reports
2023-06-26 • Scientific Reports
In areas of moderate to intense Plasmodium falciparum transmission, malaria in pregnancy remains a significant cause of low birth weight, stillbirth, and severe anaemia. Previously, feta...

Perceived barriers to early presentation and symptom-specific time to seek medical advice for possible colorectal cancer symptoms among Palestinians

Elshami M, Ayyad M, Hamdan FK, Alser M, Al-Slaibi I,  et al.
2023-04-27 • Scientific Reports
2023-04-27 • Scientific Reports
This study explored the anticipated time to seek medical advice for possible colorectal cancer (CRC) signs/symptoms and its association with CRC symptom awareness. In addition, it examin...

Immune responses to an oral cholera vaccine in internally displaced persons in South Sudan

Iyer AS, Ryan ET, Martin S, Legros D, Lessler J,  et al.
2016-10-24 • Scientific Reports
2016-10-24 • Scientific Reports
Despite recent large-scale cholera outbreaks, little is known about the immunogenicity of oral cholera vaccines (OCV) in African populations, particularly among those at highest cholera ...

Molecular epidemiology of hepatitis C virus in Cambodia during 2016–2017

Nouhin J, Iwamoto M, Prak S, Doussett JP, Phon K,  et al.
2019-05-13 • Scientific Reports
2019-05-13 • Scientific Reports
In Cambodia, little epidemiological data of hepatitis C virus (HCV) is available. All previous studies were limited to only small or specific populations. In the present study, we perfor...

Prevalence and risk factors of brucellosis among febrile patients attending a community hospital in south western Uganda

Migisha R, Nyehangane D, Page AL, Zuniga-Ripa A, Conde-Alvarez R,  et al.
2018-10-18 • Scientific Reports
2018-10-18 • Scientific Reports
Human brucellosis, a chronic disease contracted through contact with animals and consuption of unpasteurized dairy products is underreported in limited-resource countries. This cross-sec...

Higher risk Sexual Behaviour is associated with Unawareness of HIV-positivity and lack of Viral Suppression - implications for Treatment as Prevention

Huerga H, Venables E, Ben Farhat J, van Cutsem G, Ellman T,  et al.
2017-11-23 • Scientific Reports
2017-11-23 • Scientific Reports
Efficacy of Treatment as Prevention Strategy depends on a variety of factors including individuals' likelihood to test and initiate treatment, viral load and sexual behaviour. We tested ...

Association between admission criteria and body composition among young children with moderate acute malnutrition, a cross-sectional study from Burkina Faso

Fabiansen C, Cichon B, Yaméogo CW, Iuel-Brockdorf AS, Phelan KPQ,  et al.
2020-08-06 • Scientific Reports
2020-08-06 • Scientific Reports
Children with moderate acute malnutrition (MAM) are treated based on low weight-for-length z-score (WLZ), low mid-upper arm circumference (MUAC) or both. This study aimed to assess assoc...

Estimating and predicting snakebite risk in the Terai region of Nepal through a high-resolution geospatial and One Health approach

Ochoa C, Pittavino M, Martins SB, Alcoba G, Bolon I,  et al.
2021-12-13 • Scientific Reports
2021-12-13 • Scientific Reports
Most efforts to understand snakebite burden in Nepal have been localized to relatively small areas and focused on humans through epidemiological studies. We present the outcomes of a geo...

Predictive Modeling Targets Thymidylate Synthase ThyX in Mycobacterium Tuberculosis

Djaout K, Singh VK, Boum Y II, Katawera V, Becker HF,  et al.
2016-06-10 • Scientific Reports
2016-06-10 • Scientific Reports
There is an urgent need to identify new treatments for tuberculosis (TB), a major infectious disease caused by Mycobacterium tuberculosis (Mtb), which results in 1.5 million deaths each ...

Aetiology and Outcomes of Suspected Infections of the Central Nervous System in Children in Mbarara, Uganda

Page AL, Kemigisha E, Salez N, Nanjebe D, Langendorf C,  et al.
2017-06-02 • Scientific Reports
2017-06-02 • Scientific Reports
Infections of the central nervous system (CNS) are severe conditions, leading to neurological sequelae or death. Knowledge of the causative agents is essential to develop guidelines for ...

Metagenomic sequencing characterizes a wide diversity of viruses in field mosquito samples in Nigeria

Oguzie JU, Nwangwu UC, Oluniyi PE, Olumade TJ, George UE,  et al.
2022-05-10 • Scientific Reports
2022-05-10 • Scientific Reports
Mosquito vectors are a tremendous public health threat. One in six diseases worldwide is vector-borne transmitted mainly by mosquitoes. In the last couple of years, there have been activ...

Disseminated Tuberculosis Among Hospitalised HIV Patients in South Africa: A Common Condition that Can Be Rapidly Diagnosed Using Urine-Based Assays

Kerkhoff AD, Barr DA, Schutz C, Burton R, Nicol MP,  et al.
2017-09-07 • Scientific Reports
2017-09-07 • Scientific Reports
HIV-associated disseminated TB (tuberculosis) has been under-recognised and poorly characterised. Blood culture is the gold-standard diagnostic test, but is expensive, slow, and may unde...

Multi-drug resistance and high mortality associated with community-acquired bloodstream infections in children in conflict-affected northwest Nigeria

Chukwumeze F, Lenglet AD, Olubiyo R, Lawal AM, Oluyide B,  et al.
2021-10-21 • Scientific Reports
2021-10-21 • Scientific Reports
Pediatric community-acquired bloodstream infections (CA-BSIs) in sub Saharan African humanitarian contexts are rarely documented. Effective treatment of these infections is additionally ...