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Copyright © Médecins Sans Frontières
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Showing 1 - 20 of 31 Items
Showing 1 - 20 of 31 Items
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Journal Article
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Research

High incidence of intended partner pregnancy among men living with HIV in rural Uganda: Implications for safer conception services

Kaida A, Kabakyenga JK, Bwana M, Bajunirwe F, Muyindike WR,  et al.
2019-08-15 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-08-15 • Journal of Acquired Immune Deficiency Syndromes (1999)
Many men with HIV express fertility intentions and nearly half have HIV-uninfected sexual partners. We measured partner pregnancy among a cohort of men accessing antiretroviral therapy (...
Journal Article
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Review

Female Genital Schistosomiasis and HIV: Research urgently needed to improve understanding of the health impacts of this important co-infection

O'Brien DP, Ford NP, Djirmay AG, Calmy A, Victoria M,  et al.
2019-01-25 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-01-25 • Journal of Acquired Immune Deficiency Syndromes (1999)
Evidence suggests that there are important interactions between HIV and Female Genital Schistosomiasis (FGS) that may have significant effects on individual and population health. Howeve...
Journal Article
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Research

Higher Art Adherence is Associated with Lower Systemic Inflammation in Treatment-Naïve Ugandans Who Achieve Virologic Suppression

Castillo-Mancilla JR, Morrow M, Boum Y II, Byakwaga H, Haberer JE,  et al.
2018-01-16 • Journal of Acquired Immune Deficiency Syndromes (1999)
2018-01-16 • Journal of Acquired Immune Deficiency Syndromes (1999)
Residual systemic inflammation persists despite suppressive antiretroviral therapy (ART) and is associated with non-AIDS clinical outcomes. We aimed to evaluate the association between A...
Journal Article
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Letter

The challenge of retention within antiretroviral treatment programmes and the need for recent data

Grimsrud A, Wilkinson LS, Cornell M
2015-06-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2015-06-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
Journal Article
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Research

Time to initiation of antiretroviral therapy among patients with HIV-associated tuberculosis in Cape Town, South Africa

Lawn SD, Campbell L, Kaplan R, Boulle AM, Cornell M,  et al.
2011-06-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2011-06-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
We studied the time interval between starting tuberculosis treatment and commencing antiretroviral treatment (ART) in HIV-infected patients (n = 1433; median CD4 count 71 cells per micro...
Journal Article
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Research

CD4 count slope and mortality in HIV-infected patients on antiretroviral therapy: multicohort analysis from South Africa

Hoffman CJ, Schomaker M, Fox MP, Mutevedzi, Giddy J,  et al.
2013-01-22 • Journal of Acquired Immune Deficiency Syndromes (1999)
2013-01-22 • Journal of Acquired Immune Deficiency Syndromes (1999)
In many resource-limited settings monitoring of combination antiretroviral therapy (cART) is based on the current CD4 count, with limited access to HIV RNA tests or laboratory diagnostic...
Journal Article
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Research

Drug resistance and viral tropism in HIV-1 subtype C-infected patients in KwaZulu-Natal, South Africa: implications for future treatment options

Singh A, Sunpath H, Green TN, Padayachi N, Hiramen K,  et al.
2011-11-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2011-11-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND
Drug resistance poses a significant challenge for the successful application of highly active antiretroviral therapy (HAART) globally. Furthermore, emergence of HIV-1 isol...
Journal Article
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Research

Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa

Fenner L, Brinkhof MW, Keiser O, Weigel R, Cornell M,  et al.
2010-08-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2010-08-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in chi...
Journal Article
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Research

Time to AIDS from 1992 to 1999 in HIV-1-Infected Subjects with Known Date of Infection

Tassie JM, Grabar S, Lancar R, Deloumeaux J, Bentata M,  et al.
2002-05-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2002-05-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
To estimate the change in AIDS incubation time during three periods characterized by different availability of antiretroviral treatments, data from the French Hospital Database on HIV of...
Journal Article
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Research

Viral Load Monitoring as a Tool to Reinforce Adherence: A Systematic Review

Bonner K, Mezochow A, Roberts TR, Ford NP, Cohn J
2013-06-14 • Journal of Acquired Immune Deficiency Syndromes (1999)
2013-06-14 • Journal of Acquired Immune Deficiency Syndromes (1999)
Viral load monitoring has been proposed as a tool to reinforce adherence, but outcomes have never been systematically assessed.
Journal Article
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Research

Field suitability and diagnostic accuracy of the Biocentric open real-time PCR platform for dried blood spot-based HIV viral load quantification in Eswatini

Kerschberger B, Ntshalintshali N, Mpala Q, Diaz Uribe PA, Maphalala G,  et al.
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND
To assess the performance and suitability of dried blood spot (DBS) sampling using filter paper to collect blood for viral load (VL) quantification under routine condition...
Journal Article
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Short Report

High prevalence of NRTI and NNRTI drug resistance among ART-experienced, hospitalized inpatients

Bossard C, Schramm B, Wanjala S, Jain L, Mucinya G,  et al.
2021-04-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2021-04-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
Journal Article
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Research

Should urine-LAM tests be used in TB symptomatic HIV-positive patients when no CD4 count is available? A prospective observational cohort study from Malawi

Huerga H, Rucker SCM, Bastard M, Dimba A, Kamba C,  et al.
2020-01-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2020-01-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
Background: Current eligibility criteria for urine lateral-flow-lipoarabinomannan assay (LF-LAM) in ambulatory, HIV-positive patients rely on the CD4 count. We investigated the diagnosti...
Journal Article
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Research

Depression During Pregnancy and the Postpartum Among HIV-Infected Women on Antiretroviral Therapy in Uganda

Kaida A, Matthews LT, Ashaba S, Tsai AC, Kanters S,  et al.
2014-12-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2014-12-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
Among HIV-infected women, perinatal depression compromises clinical, maternal, and child health outcomes. Antiretroviral therapy (ART) is associated with lower depression symptom severit...
Journal Article
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Research

Distribution and performance of cardiovascular risk scores in a mixed population of HIV-infected and community-based HIV-uninfected individuals in Uganda

Muiru AN, Bibangambah P, Hemphill LC, Sentongo R, Kim JH,  et al.
2018-04-11 • Journal of Acquired Immune Deficiency Syndromes (1999)
2018-04-11 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND
The utility and validity of cardiovascular diseases (CVD) risk scores are not well studied in sub-Saharan Africa. We compared and correlated CVD risk scores with carotid i...
Journal Article
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Research

Pooled HIV-1 Viral Load Testing Using Dried Blood Spots to Reduce the Cost of Monitoring Antiretroviral Treatment in a Resource-Limited Setting

Pannus P, Fajardo E, Metcalf CJ, Coulborn R M, Duran LT,  et al.
2013-07-25 • Journal of Acquired Immune Deficiency Syndromes (1999)
2013-07-25 • Journal of Acquired Immune Deficiency Syndromes (1999)
: Rollout of routine HIV-1 viral load monitoring is hampered by high costs and logistical difficulties associated with sample collection and transport. New strategies are needed to overc...
Journal Article
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Research

Feasibility of using tuberculin skin test screening for initiation of 36-month isoniazid preventive therapy in HIV-infected patients in resource-constrained settings

Huerga H, Vasquez B, Mekiedje C, Mueller YK, Ferlazzo G,  et al.
2015-11-11 • Journal of Acquired Immune Deficiency Syndromes (1999)
2015-11-11 • Journal of Acquired Immune Deficiency Syndromes (1999)
Journal Article
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Research

Risk charts to guide targeted HIV-1 viral load monitoring of ART: development and validation in patients from resource-limited settings

Koller M, Fatti G, Chi BH, Keiser O, Hoffman CJ,  et al.
2015-07-07 • Journal of Acquired Immune Deficiency Syndromes (1999)
2015-07-07 • Journal of Acquired Immune Deficiency Syndromes (1999)
Journal Article
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Research

Similar mortality and reduced loss to follow-up in integrated compared with vertical programs providing antiretroviral treatment in sub-saharan Africa

Greig J, O'Brien DP, Ford NP, Spelman T, Sabapathy K,  et al.
2011-11-30 • Journal of Acquired Immune Deficiency Syndromes (1999)
2011-11-30 • Journal of Acquired Immune Deficiency Syndromes (1999)
Vertical HIV programs have achieved good results but may not be feasible or appropriate in many resource-limited settings. Médecins sans Frontières has treated HIV in vertical programs s...
Journal Article
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Research

Who Needs to Be Targeted for HIV Testing and Treatment in KwaZulu-Natal? Results From a Population-Based Survey

Huerga H, van Cutsem G, Ben Farhat J, Reid M, Bouhenia M,  et al.
2016-12-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2016-12-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
Identifying gaps in HIV testing and treatment is essential to design specific strategies targeting those not accessing HIV services. We assessed the prevalence and factors associated wit...