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Copyright © Médecins Sans Frontières
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Showing 1 - 3 of 3 Items
Showing 1 - 3 of 3 Items
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Journal Article
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Research

Population pharmacokinetics of pediatric lopinavir/ritonavir oral pellets in children living with HIV in Africa

Chupradit S, Wamalwa DC, Maleche‐Obimbo E, Kekitiinwa AR, Mwanga‐Amumpaire J,  et al.
2024-05-01 • Clinical Pharmacology & Therapeutics
2024-05-01 • Clinical Pharmacology & Therapeutics
Antiretroviral therapy for children living with HIV (CLHIV) under 3 years of age commonly includes lopinavir/ritonavir (LPV/r). However, the original liquid LPV/r formulation has taste a...
Journal Article
|
Research

Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether-lumefantrine for uncomplicated malaria

Chotsiri P, Denoeud-Ndam L, Baudin E, Guindo O, Diawara H,  et al.
2019-06-01 • Clinical Pharmacology & Therapeutics
2019-06-01 • Clinical Pharmacology & Therapeutics
Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub‐Saharan African children and may affect the pharmacology of antimalarial drugs....
Journal Article
|
Research

Adherence and population pharmacokinetic properties of amodiaquine when used for Seasonal Malaria Chemoprevention in African children

Ding J, Coldiron ME, Assao B, Guindo O, Blessborn D,  et al.
2019-10-25 • Clinical Pharmacology & Therapeutics
2019-10-25 • Clinical Pharmacology & Therapeutics
Poor adherence to seasonal malaria chemoprevention (SMC) might affect the protective effectiveness of SMC. Here, we evaluated the population pharmacokinetic properties of amodiaquine and...